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Balancing efficacy and safety: The challenges of mRNA drugs and vaccines in modern medicine

Researchers analyzed the toxicity concerns and advancements in mRNA therapeutics, focusing on their cellular toxicity, reactogenicity, and distribution, and discussed the challenges and benefits of mRNA research.

24 Jan 2024

NHS health checks linked to reduced risk of heart, brain, kidney, and liver diseases

A study analyzing UK Biobank data found that individuals who underwent the NHS health evaluation had a lower long-term risk of various diseases and mortality compared to those who did not participate in the assessment.

24 Jan 2024

RNA Therapies in Liver Disease: Insights from Ochre Bio's CEO

In this interview, we speak with Jack O'Meara, co-founder and CEO of Ochre Bio, a pioneering force in liver disease treatment. O'Meara shares insights into Ochre Bio's innovative RNA therapies, their approach to tackling liver disease, and the company's vision for the future.

24 Jan 2024

CN Bio and Altis Biosystems partner to develop next-generation human Gut/Liver in vitro model for advanced ADME studies

CN Bio and Altis Biosystems, Inc. (“Altis”), leading developers of in vitro human organ models that optimize the accuracy and efficiency of drug development, today announced a strategic partnership.

24 Jan 2024

Dietary carotenoids may reduce risk of non-alcoholic fatty liver disease, study suggests

Study found no direct link between total dietary vitamin A intake and non-alcoholic fatty liver disease (NAFLD) risk, but observed an inverse correlation between provitamin A carotenoid consumption and NAFLD risk.

23 Jan 2024

Significant link found between recent weight loss and increased cancer risk

Study reveals that recent weight loss in individuals aged 40 or older is significantly associated with an increased risk of cancer diagnosis within the following year, particularly upper gastrointestinal cancers.

23 Jan 2024

3D-printed liver model paves way for new MASH treatments

Metabolic dysfunction- associated steatohepatitis, or MASH, is an inflammatory, liver-scarring disease that has reached epidemic proportions, with an estimated 1.5% to 6.5% of U.S. adults afflicted by the condition, and roughly 24% of adults having nonalcoholic fatty liver disease (NAFLD).

23 Jan 2024

Unintentional weight loss linked to increased risk of cancer diagnosis

Unintentional weight loss is associated with an increase in the risk of a cancer diagnosis within the coming year, according to a study from Dana-Farber Cancer Institute.

23 Jan 2024

Study links GLP1 agonists to reduced risk of severe liver disease in diabetic patients

Ozempic and other GLP1 agonists are associated with a reduced risk of developing cirrhosis and liver cancer in people with type 2 diabetes and chronic liver disease, according to a nationwide study from Karolinska Institutet in Sweden published in the journal Gut.

23 Jan 2024

Body mass index found to mediate causal associations between Helicobacter pylori infections and coronary artery disease risk

Coronary heart disease (CHD) and H. Pylori.

23 Jan 2024

CN Bio and Altis Biosystems partner to develop next-generation human Gut/Liver in vitro model for advanced ADME studies

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From CN-Bio 23 Jan 2024

Study identifies genetic variants that influence response to preterm birth treatment

A UC San Francisco-led study has for the first time identified genetic variants that predict whether patients will respond to treatment for preterm birth, a condition that affects one in 10 infants born in the United States.

22 Jan 2024

NHS Health Check linked to lower disease rates and mortality, study shows

Attending an NHS Health Check appointment -; a preventative screening programme offered for free in the UK -; is associated with both a decreased risk of dying and a decreased risk of several diseases, including dementia and liver cirrhosis.

22 Jan 2024

Patient-specific "organ-on-chip" aims to accelerate research on cholangiocarcinoma

It is only a few centimeters in size and can be held between two fingers, but in the micro-channels carved inside it, it's hidden a three-dimensional and highly faithful model of a biliary tract cancer called cholangiocarcinoma, complete with its tumor microenvironment.

22 Jan 2024

Cancer drug holds promise for shrinking polycystic kidney cysts

Autosomal dominant polycystic kidney disease (ADPKD), the most common form of polycystic kidney disease, can lead to kidney enlargement and eventual loss of function.

22 Jan 2024

Aerobic exercise could help combat non-alcoholic fatty liver disease

According to a study conducted on animal models and published in the journal Metabolism, aerobic exercise could help fight the non-alcoholic fatty liver disease, the most common liver disease worldwide: it affects nearly 24% of the global population and it usually causes a certain stigma among the affected people.

22 Jan 2024

Liver News and Research

Balancing efficacy and safety: The challenges of mRNA drugs and vaccines in modern medicine

NHS health checks linked to reduced risk of heart, brain, kidney, and liver diseases

RNA Therapies in Liver Disease: Insights from Ochre Bio's CEO

CN Bio and Altis Biosystems partner to develop next-generation human Gut/Liver in vitro model for advanced ADME studies

Dietary carotenoids may reduce risk of non-alcoholic fatty liver disease, study suggests

Significant link found between recent weight loss and increased cancer risk

3D-printed liver model paves way for new MASH treatments

Unintentional weight loss linked to increased risk of cancer diagnosis

Study links GLP1 agonists to reduced risk of severe liver disease in diabetic patients

Body mass index found to mediate causal associations between Helicobacter pylori infections and coronary artery disease risk

CN Bio and Altis Biosystems partner to develop next-generation human Gut/Liver in vitro model for advanced ADME studies

Study identifies genetic variants that influence response to preterm birth treatment

NHS Health Check linked to lower disease rates and mortality, study shows

Patient-specific "organ-on-chip" aims to accelerate research on cholangiocarcinoma

Cancer drug holds promise for shrinking polycystic kidney cysts

Aerobic exercise could help combat non-alcoholic fatty liver disease

Sweetener 'Stevia' does not alter gut microbiota composition, confirms new study

HoloCare launches 3D surgical holograms across the UK and Europe

New oral insulin delivered via nano-carriers could soon replace injections

The crucial need for ongoing COVID-19 booster vaccination in vulnerable populations

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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