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University of Liverpool introduces HEP i-chart for HCV patients

The University of Liverpool has launched an iphone app, HEP i-chart, that provides Hepatitis C (HCV) patients with quick and easy access to the latest information about drug interactions.

23 Nov 2011

Study: Vaccine development efforts currently focus on incidence rather than mortality rates

Drug companies currently developing therapeutic cancer vaccines may be determining the cancers they target based on the number of annual cases, not the number of deaths they cause.

22 Nov 2011

Non-alcoholic fatty liver disease does not appear to affect survival

Non-alcoholic fatty liver disease (NAFLD) is a common condition associated with obesity and heart disease long thought to undermine health and longevity. But a new study by Johns Hopkins researchers suggests the condition does not affect survival.

22 Nov 2011

New 'triggered imaging' enables physicians to better target tumors during radiosurgery

A new type of "triggered imaging" technology enables University of Alabama at Birmingham physicians to better target tumors during radiosurgery and lessens the risk of injury to surrounding lung tissue.

22 Nov 2011

CUMC presents 2011 Naomi Berrie Award to UMDNJ researcher

Columbia University Medical Center (CUMC) presented the 2011 Naomi Berrie Award to Barry E. Levin, MD, a University of Medicine & Dentistry of New Jersey researcher whose work focuses on the mechanisms by which specialized metabolic-sensing neurons regulate glucose and energy homeostasis. Junior investigator Kazuhisa Watanabe, at Columbia University Medical Center, received a Berrie Fellow award.

22 Nov 2011

Scientists search for main culprit behind Sj-gren's syndrome

Researchers want to find the main culprit behind the dry, irritated eyes, mouth, throat, skin, nose and more afflicting 1-3 percent of the population.

22 Nov 2011

Positive preliminary results from Alnylam's ALN-TTR01 Phase I clinical trial for TTR-mediated amyloidosis

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today positive preliminary results from its Phase I clinical trial with ALN-TTR01, an RNAi therapeutic targeting transthyretin (TTR) for the treatment of TTR-mediated amyloidosis (ATTR).

21 Nov 2011

American high school students earn top honors for liver disease and brain injury research

The shortlist of contenders for the highest science honor awarded to American high school students narrowed tonight as the winners of the Siemens Competition in Math, Science & Technology Region 3 Finals were announced.

21 Nov 2011

Scientists solve mystery behind why people with defective hemoglobin do not contract malaria

Why do people with a hereditary mutation of the red blood pigment hemoglobin not contract severe malaria? Scientists in the group headed by Prof. Michael Lanzer of the Department of Infectious Diseases at Heidelberg University Hospital have now solved this mystery.

19 Nov 2011

New class of malaria drugs could be used as both prevention, treatment, study shows

"A group of researchers led by Novartis AG have discovered novel malaria compounds that may prove to be more efficient than currently available treatments and could be used as a prophylactic," the Wall Street Journal reports.

19 Nov 2011

EUSA Pharma receives FDA approval for Erwinaze to treat ALL

The U.S. Food and Drug Administration today approved Erwinaze to treat patients with acute lymphoblastic leukemia (ALL), who have developed an allergy (hypersensitivity) to E. coli derived asparaginase and pegaspargase chemotherapy drugs used to treat ALL.

18 Nov 2011

Researchers discover new class of antimalarial compounds

Researchers have discovered a group of chemical compounds that might one day be developed into drugs that can treat malaria infection in both the liver and the bloodstream.

18 Nov 2011

Scientists discover family of chemical compounds that could prevent malaria

A international team led by scientists from the Genomics Institute of the Novartis Research Foundation (GNF) and The Scripps Research Institute has discovered a family of chemical compounds that could lead to a new generation of antimalarial drugs capable of not only alleviating symptoms but also preventing the deadly disease.

17 Nov 2011

New possibilities for relief from digestive diseases

As a researcher in neurogastroenterology for 40 years, professor Khalil Bitar has spent his professional life studying the causes of perplexing and what frequently become embarrassing problems for humans—issues such as constipation, diarrhea and colon disease.

17 Nov 2011

Aurora kinase inhibitor may treat neuroendocrine prostate cancer

An international team of researchers led by clinicians at Weill Cornell Medical College have discovered a genetic Achilles' heel in an aggressive type of prostate cancer -- a vulnerability they say can be attacked by a targeted drug that is already in clinical trials to treat other types of cancers.

17 Nov 2011

Leading alcohol researchers to discuss latest genetic findings at Loyola meeting

Leading alcohol researchers from the United States and Canada will discuss their latest findings at an all-day meeting Nov. 18 at Loyola University Chicago Stritch School of Medicine.

16 Nov 2011

Mirna reports new preclinical data of miRNA-based therapeutic candidate for hepatocellular carcinoma

Mirna Therapeutics, Inc., a biotechnology company pioneering microRNA replacement therapy for cancer, announced the presentation today of new preclinical data on the development of a miRNA-based therapeutic candidate for primary liver cancer at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics in San Francisco, CA.

16 Nov 2011

Insulin sensitivity in the ovaries and the pituitary linked to infertility

Infertility is common among obese women, but the reasons remain poorly understood and few treatments exist. Now a team of Johns Hopkins Children's Center scientists, conducting experiments in mice, has uncovered what they consider surprising evidence that insulin resistance, long considered a prime suspect, has little to do with infertility in women with type-2 diabetes, polycystic ovary syndrome and metabolic syndrome, all obesity-related conditions.

16 Nov 2011

Molecular level insights into connection between cancer and diabetes

Developing type 2 diabetes is a lengthy process. An early sign that it has begun is high levels of insulin in the blood. As long as the insulin-producing beta cells are able to compensate for the increased demand, for example when the individual is overweight, the blood sugar levels remain normal. It is not until the capacity for insulin secretion falls below the level needed that type 2 diabetes becomes a fact. The latter stage generally goes quickly, as the stressed beta cells work themselves to death.

16 Nov 2011

Silibinin stops spread of lung cancer in mice

Tissue with wound-like conditions allows tumors to grow and spread. In mouse lung cancer cells, treatment with silibinin, a major component of milk thistle, removed the molecular billboards that signal these wound-like conditions and so stopped the spread of these lung cancers, according to a recent study published in the journal Molecular Carcinogenesis.

16 Nov 2011

Liver News and Research

University of Liverpool introduces HEP i-chart for HCV patients

Study: Vaccine development efforts currently focus on incidence rather than mortality rates

Non-alcoholic fatty liver disease does not appear to affect survival

New 'triggered imaging' enables physicians to better target tumors during radiosurgery

CUMC presents 2011 Naomi Berrie Award to UMDNJ researcher

Scientists search for main culprit behind Sj-gren's syndrome

Positive preliminary results from Alnylam's ALN-TTR01 Phase I clinical trial for TTR-mediated amyloidosis

American high school students earn top honors for liver disease and brain injury research

Scientists solve mystery behind why people with defective hemoglobin do not contract malaria

New class of malaria drugs could be used as both prevention, treatment, study shows

EUSA Pharma receives FDA approval for Erwinaze to treat ALL

Researchers discover new class of antimalarial compounds

Scientists discover family of chemical compounds that could prevent malaria

New possibilities for relief from digestive diseases

Aurora kinase inhibitor may treat neuroendocrine prostate cancer

Leading alcohol researchers to discuss latest genetic findings at Loyola meeting

Mirna reports new preclinical data of miRNA-based therapeutic candidate for hepatocellular carcinoma

Insulin sensitivity in the ovaries and the pituitary linked to infertility

Molecular level insights into connection between cancer and diabetes

Silibinin stops spread of lung cancer in mice

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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