Liver News and Research

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ProFibrix Fibrocaps effectively reduces bleeding in liver resection surgery

ProFibrix B.V., a leader in the development of innovative products for hemostasis, today announced that its multicenter Phase II clinical trial with Fibrocaps in liver resection surgery resulted in a highly statistically significant 50% reduction in mean time to hemostasis (TTH) compared to active control.

15 Nov 2011

New clues about connections among fat, inflammation and insulin resistance

In a new study, scientists report that they substantially curbed weight gain, improved metabolism, and improved the efficacy of insulin in mice by engineering them to express a specific human enzyme in their fat tissue. Although the obesity prevention came at the significant cost of widespread inflammation, the research offers new clues about the connections among obesity, insulin resistance and type 2 diabetes, and inflammation.

14 Nov 2011

A dangerous combo – schoolies warned

Pharmacy researchers at the University of Sydney are warning HSC students to take it easy on caffeine, alcohol and smoking during Schoolies Week, particularly young women using oral contraception.

14 Nov 2011

A shot to lower 'bad' cholesterol

Patients unable to control their cholesterol levels with medications may someday be able to lower their "bad" cholesterol with a shot, according to research presented at the American Heart Association's Scientific Sessions 2011.

14 Nov 2011

China Pharma third quarter revenue increases 12% to $21.0 million

China Pharma Holdings, Inc., a specialty pharmaceuticals company in China, today announced financial results for the quarter ended September 30, 2011.

11 Nov 2011

Dramatic rise in obesity, fatty liver disease increases need for transplants

The dramatic rise in obesity is leading to more fatty liver disease in the United States, increasing the need for more transplants at a time when there already is a severe shortage of donated organs.

11 Nov 2011

Conference highlights advances in evidence-based integrative therapies for cancer

Today the Society for Integrative Oncology highlighted top research findings presented at the Eighth International Conference this week in Cleveland, Ohio. More than 80 abstracts will be presented at the annual meeting, which will be keynoted by National Institutes of Health Director, Francis Collins, MD, PhD.

11 Nov 2011

NCoR deficiency may pump up muscles and prevent diabetes

Two independent studies in the Nov. 11 issue of the journal Cell, a Cell Press publication, suggest a common way to pump up muscles and prevent diabetes. The key is a molecule required for fine-tuning metabolism by selectively and subtly modifying core metabolic programs.

11 Nov 2011

N-acetylcysteine plus cortisone shows promise against acute alcoholic hepatitis

Acute alcoholic hepatitis is one of the most serious forms of alcoholic liver disease, affecting individuals with chronic excessive alcohol consumption, which generally equates to more than 50 grams of alcohol per day, over a period of more than three to six months. The disease is characterized by liver failure and acute jaundice (icterus), which may induce a coma through liver failure and an ensuing death rate of between 40-45% within the first six months.

11 Nov 2011

New unsuspected role for nuclear receptor corepressor protein

By knocking out a key regulatory protein, scientists at the University of California, San Diego School of Medicine and the Ecole Polytechnique Federale de Lausanne (EPFL) in Switzerland dramatically boosted insulin sensitivity in lab mice, an achievement that opens a new door for drug development and the treatment of diabetes.

11 Nov 2011

Researchers uncover mechanism that governs cell specialization

Researchers at then Albert Einstein College of Medicine of Yeshiva University have uncovered a mechanism that governs how cells become specialized during development.

10 Nov 2011

Drug effectively combats obesity in “couch potato” monkeys” Study

According a new study an experimental anti-cancer drug could help fight obesity. The drug chokes off the blood supply to fat cells and helped obese monkeys slim down in the experiments.

10 Nov 2011

New studies could fundamentally change medical treatment of liver cancer

Scientists at the Helmholtz Zentrum München have played a major role in two studies that could fundamentally change the medical treatment of liver cancer. Doctors are now able to determine the degree of aggressiveness of the tumour in the early stages and can thus devise an individualised treatment plan.

10 Nov 2011

Combination of azacitidine and entinostat shows promise against NSCLC

A new type of therapy aimed at reversing the gene-silencing that promotes cancer-cell growth has shown promising results in a small clinical trial conducted by researchers at the Johns Hopkins Kimmel Cancer Center.

10 Nov 2011

Merck's NEXPLANON 68 mg now available in the U.S.

Merck today announced that NEXPLANON (etonogestrel implant) 68 mg, a long-acting, progestin-only single-rod hormonal contraceptive, is now available in the United States.

10 Nov 2011

Online platform for automatic analysis of microscopic image data

Under the microscope lies a specimen of a liver. Deep in concentration, a student is analyzing the structure of the tissue when the university official asks her to finish up - the lab is about to close. This is a situation that may be familiar to many students. After all, the examination of specimens is an important course component; to practice and consolidate the theory presented in lectures.

9 Nov 2011

Adult living donor liver transplantations safe for donors

Desperately needed adult living donor liver transplantation is a safe surgery for the donor, according to researchers at Henry Ford Hospital.

9 Nov 2011

VCU pediatric surgeons successfully separate Dominican twin toddlers

A team of Virginia Commonwealth University pediatric surgeons today successfully completed the separation of 19-month-old conjoined twins Maria and Teresa Tapia of the Dominican Republic.

9 Nov 2011

Johns Hopkins researchers unravel how breast cancer metastasizes

The spread of breast cancer is responsible for more than 90 percent of breast cancer deaths. Now, the process by which it spreads—or metastasizes—has been unraveled by researchers at Johns Hopkins. Reporting in two papers, the researchers have discovered the switch that enables breast cancer cells to travel to and be received in the lungs.

9 Nov 2011

Ligand third quarter total revenues decrease to $5.7 million

Ligand Pharmaceuticals Incorporated today announced financial results for the three and nine months ended September 30, 2011 and provided a business update.

9 Nov 2011