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Viewpoints: Judge Vinson's decision and Sarah Palin, Voting Rights Act; States' Medicaid 'burden;' Global fund controversy

With news coverage focused on Federal District Judge Roger Vinson's decision Monday to declare the health care reform law unconstitutional, it might be easy to miss this week's news from another federal courthouse: opponents of the Voting Rights Act have renewed their efforts to have that law declared unconstitutional, too.

5 Feb 2011

U-M Medical School earns $368.7 million in NIH research funding during federal fiscal year 2010

University of Michigan Medical School physicians and scientists earned more than $368.7 million in National Institutes of Health research funding in federal fiscal year 2010, according to NIH data. In all, the School's faculty brought in $481.8 million in research funding from all sources in U-M fiscal year 2010.

5 Feb 2011

EntreMed announces publication of ENMD-2076 Phase 1 results against solid tumors in AACR journal

EntreMed, Inc., today announced the publication of key papers on the clinical and preclinical development of ENMD-2076, an Aurora A/angiogenic kinase inhibitor. The clinical data were published in the December 3, 2010 on-line issue of the American Association for Cancer Research journal, Clinical Cancer Research, and are expected to appear soon in the print version of the publication.

4 Feb 2011

Scientists discover how stressed cells boost thrombin production

In our not-so-distant evolutionary past, stress often meant imminent danger, and the risk of blood loss, so part of our body's stress response is to stock-pile blood-clotting factors. Scientists in the Molecular Medicine Partnership Unit, a collaboration between the European Molecular Biology Laboratory in Heidelberg, Germany, and the University of Heidelberg Medical Centre, have discovered how stressed cells boost the production of the key blood-clotting factor, thrombin.

4 Feb 2011

Lampreys may have dual immune defense system similar to that of humans

Biologists have discovered that primitive, predatory lampreys have structures within their gills that play the same role as the thymus, the organ where immune cells called T cells develop in mammals, birds and fish.

4 Feb 2011

Scientists discover how stressed cells boost production of key blood-clotting factor, thrombin

Scientists in a collaboration between EMBL Heidelberg and the University of Heidelberg Medical Centre have discovered how stressed cells boost the production of the key blood-clotting factor, thrombin. Their work, published today in Molecular Cell, shows how cancer cells may be taking advantage of this process, and opens new possibilities for fighting back against cancer and septicaemia.

4 Feb 2011

How body's first line of defence distinguishes between microbes and own structures

This week, the highly-respected US Academy of Sciences journal (PNAS) published an article describing how the first line of defence of the human immune system distinguishes between microbes and the body's own structures.

4 Feb 2011

New 'skin gun' treats burns with stem cells

A revolutionary new "skin gun" developed to treat burns could be the latest in a remarkable string of stem-cell breakthroughs poised to change the face of medicine, says Emerging Healthcare Solutions President and CEO Cindy Morrissey.

4 Feb 2011

American Cancer Society report released on World Cancer Day

A new American Cancer Society report says cancers associated with lifestyles and behaviors related to economic development, including lung, breast, and colorectal cancers, will continue to rise in developing countries if preventive measures are not widely applied. The finding comes from the second edition of Global Cancer Facts & Figures and its academic publication, Global Cancer Statistics, published in CA: A Cancer Journal for Clinicians.

4 Feb 2011

More needs to be done globally to fight cancer

WHILE cancer statistics for the last 10 years make encouraging reading, more needs to be done globally to fight the killer disease.

4 Feb 2011

Roundup: N.Y., Texas, Calif. Medicaid plans spark protests; Conn. nursing homes; Fla. Medical Board

Gov. Andrew Cuomo's effort to strip lawmakers of power over the state's Medicaid program is facing a barrage of criticism in both houses and parties. Lawmakers on Wednesday described the governor's Medicaid proposal as an intrusion on their powers and said they would block it from becoming law.

4 Feb 2011

Scientists unravel mystery about how new tumors in individuals with breast cancer take root

In a discovery that may lead to a new treatment for breast cancer that has spread to the bone, a Princeton University research team has unraveled a mystery about how these tumors take root.

4 Feb 2011

Study finds contradictory role of RIP1 protein in the liver during sepsis

Researchers from Rhode Island Hospital have identified a protein that plays a dual role in the liver during sepsis. The protein, known as RIP1, acts both as a "death switch" and as a pro-survival mechanism. The ability to identify the triggers for these functions may play a key role in treating sepsis in the future. The study is published online in advance of print in the journal Shock.

3 Feb 2011

Damaged heart rebuilt with heart stem cells from children with congenital heart disease

A new study, revealing that heart stem cells from children with congenital heart disease were able to rebuild the damaged heart in the laboratory, could provide a new outlet for Emerging Healthcare Solutions' NASA bioreactor.

2 Feb 2011

New robotic technique can better predict tumors during radiotherapy, prevent severity of side effects

Medical physicists at Thomas Jefferson University and Jefferson's Kimmel Cancer Center have demonstrated a new real-time tumor tracking technique that can help minimize the amount of radiation delivered to surrounding healthy tissue in a patient—up to 50 percent less in some cases—and maximize the dose the tumor receives.

2 Feb 2011

Scientists discover breast cancer cells that dodge immune system, promote tumor growth

Scientists discovered a new way breast cancer cells dodge the immune system and promote tumor growth, providing a fresh treatment target in the fight against the disease. While comparable mechanisms to avoid the immune system have been identified in mice with breast and other cancers, the study tested human breast tumor cells, putting researchers closer to understanding how the disease progresses in real patients.

2 Feb 2011

FDA, Optivia collaborate to examine effect of dietary supplements in drug-induced liver injury

Optivia Biotechnology, a leading provider of in vitro transporter assay services, today announced that the company and the U.S. Food and Drug Administration have signed a collaboration agreement to assess the effect of dietary supplements on key drug transporters.

1 Feb 2011

Octreotide inhibits HepG2 proliferation, study confirms

Hepatocellular carcinoma (HCC) is the fifth most common malignancy in the world and is estimated to cause approximately half a million deaths annually. Undoubtedly, the best available treatment for all liver tumors is complete surgical resection. However, the synthetic somatostatin analogue octreotide has been found effective in inhibiting tumor growth in a variety of experimental models. It has been reported that octreotide inhibits the proliferation and induces apoptosis of different HCC cell lines in vitro.

1 Feb 2011

French guy says Parkinson’s drug induced gambling and gay sex addiction, tries to sue GSK for $610,000

GlaxoSmithKline is being sued this week by a French father-of-two, alleging the British pharmaceutical firm’s drug – Reqip (Ropirnirole) to treat Parkinson’s disease turned him into a gay sex and gambling addict. Parkinson’s disease is a seriously and progressively debilitating disease that leads to tremors, slowing of movements and ultimately total immobility.

1 Feb 2011

Study finds E2F5 transcription factor commonly overexpressed in primary human HCC

E2F5 is a member of the E2F transcription factor family, and plays a key role in cell growth and proliferation. Overexpression of E2F5 has been reported in various human cancers, but not in liver cancer, and its biological implication is largely unknown. It is not known whether E2F5 plays a tumor suppressor role or an oncogenic role.

1 Feb 2011

Liver News and Research

Viewpoints: Judge Vinson's decision and Sarah Palin, Voting Rights Act; States' Medicaid 'burden;' Global fund controversy

U-M Medical School earns $368.7 million in NIH research funding during federal fiscal year 2010

EntreMed announces publication of ENMD-2076 Phase 1 results against solid tumors in AACR journal

Scientists discover how stressed cells boost thrombin production

Lampreys may have dual immune defense system similar to that of humans

Scientists discover how stressed cells boost production of key blood-clotting factor, thrombin

How body's first line of defence distinguishes between microbes and own structures

New 'skin gun' treats burns with stem cells

American Cancer Society report released on World Cancer Day

More needs to be done globally to fight cancer

Roundup: N.Y., Texas, Calif. Medicaid plans spark protests; Conn. nursing homes; Fla. Medical Board

Scientists unravel mystery about how new tumors in individuals with breast cancer take root

Study finds contradictory role of RIP1 protein in the liver during sepsis

Damaged heart rebuilt with heart stem cells from children with congenital heart disease

New robotic technique can better predict tumors during radiotherapy, prevent severity of side effects

Scientists discover breast cancer cells that dodge immune system, promote tumor growth

FDA, Optivia collaborate to examine effect of dietary supplements in drug-induced liver injury

Octreotide inhibits HepG2 proliferation, study confirms

French guy says Parkinson’s drug induced gambling and gay sex addiction, tries to sue GSK for $610,000

Study finds E2F5 transcription factor commonly overexpressed in primary human HCC

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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