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FDA approves Gilead's antiretroviral Viread for hepatitis B

Gilead Sciences on Monday announced that it has received FDA approval to market its antiretroviral drug Viread as a hepatitis B treatment, the AP/International Herald Tribune reports (AP/International Herald Tribune, 8/12).

13 Aug 2008

Isis Pharmaceuticals trials C-reactive protein drug

Isis Pharmaceuticals, Inc. announced today it has initiated a Phase 1 study of ISIS 353512, an antisense drug that inhibits the production of C-reactive protein (CRP). CRP levels are frequently elevated in patients with a variety of diseases including cardiovascular disease, Crohn's disease, rheumatoid arthritis and end-stage renal disease.

13 Aug 2008

Precisely targeted radiation therapy can control limited cancer spread

Precisely targeted radiation therapy can eradicate all evidence of disease in selected patients with cancer that has spread to only a few sites, suggests the first published report from an ongoing clinical trial.

12 Aug 2008

In-depth review of current research on the health effects of vitamin D

Despite considerable progress in research to understand the health effects of vitamin D, experts convened by the NIH to review the available data found major gaps in the evidence. The data are strongest in the area of bone health among elderly men and post-menopausal women, suggesting that increased vitamin D intake can improve bone health and prevent falls. For other age groups and health issues, though, it is too early to say conclusively whether more vitamin D might be beneficial.

12 Aug 2008

Brits told by the NHS their lives will not be saved if the cost is too much

An announcement by government authorities in the UK that drugs which are too expensive should not be prescribed even if they prolong life, because the money could be better spent elsewhere, has caused an uproar.

11 Aug 2008

Viread approved for chronic hepatitis B

The FDA has approved Viread (tenofovir disoproxil fumarate) as a treatment option for adults with chronic hepatitis B, a serious liver disease.

11 Aug 2008

Low vitamin D levels substantially increase risk of death

Researchers at Johns Hopkins are reporting what is believed to be the most conclusive evidence to date that inadequate levels of vitamin D, obtained from milk, fortified cereals and exposure to sunlight, lead to substantially increased risk of death.

11 Aug 2008

Therapies which boost the clearance of faulty proteins in cells may slow down ageing

Scientists say as people age, their cells become less efficient at getting rid of damaged protein and the result is a buildup of toxic material; this is particularly apparent in Alzheimer's, Parkinson's disease and other neurodegenerative disorders associated with ageing.

11 Aug 2008

Early treatment key to combating hepatitis C virus

Canadian researchers have shown that patients who receive early treatment for Hepatitis C virus (HCV) within the first months following an infection, develop a rapid poly-functional immune response against HCV similar to when infection is erradicted spontaneously, according to a new study published in the Journal of Virology.

10 Aug 2008

Scientists stop age-related decline in an entire organ

As people age, their cells become less efficient at getting rid of damaged protein - resulting in a buildup of toxic material that is especially pronounced in Alzheimer's, Parkinson's disease, and other neurodegenerative disorders.

10 Aug 2008

Discovery of obesity genes

A study of 228 women has revealed genetic variants responsible for body shape. Based on work in the fruit fly Drosophila melanogaster, research published in the open access journal BMC Genetics identifies natural variation in the human LAMA5 gene as a key determinant of weight.

10 Aug 2008

A new target for malaria drugs

The malaria parasite has waged a successful guerrilla war against the human immune system for eons, but a study in this week's Journal of Biological Chemistry has exposed one of the tricks malaria uses to hide from the immune proteins, which may aid in future drug development.

4 Aug 2008

First NY to LA living-donor transplant chain results in three lifesaving kidney transplants at UCLA

The lives of three Los Angeles-area kidney transplant patients were transformed by one of the West Coast's first three-way living donor kidney transplant chains, made possible through the generosity of a non-directed, altruistic kidney donor from New York City -- announced today at a joint news conference.

4 Aug 2008

Epilepsy drug gabapentin may reduce insomnia in recovering alcoholics

It's a Catch-22 of the highest order. People with alcohol problems often use alcohol to get to sleep -- but it actually keeps them from getting good-quality sleep all night long.

4 Aug 2008

New studies examine use of the nucleoside polymerase inhibitor, R1626, to the standard therapy for hepatitis C

Two new studies examine the use of the nucleoside polymerase inhibitor, R1626, to the standard therapy for hepatitis C. The reports appear in the August issue of Hepatology, a journal published by John Wiley & Sons on behalf of the American Association for the Study of Liver Diseases (AASLD).

31 Jul 2008

Warfarin may prevent liver failure in hepatitis C

The drug warfarin may help prevent liver failure in thousands of people with Hepatitis C, according to new research.

31 Jul 2008

Ultra-miniature bialy-shaped drug delivery particles

Ultra-miniature bialy-shaped particles - called nanobialys because they resemble tiny versions of the flat, onion-topped rolls popular in New York City - could soon be carrying medicinal compounds through patients' bloodstreams to tumors or atherosclerotic plaques.

29 Jul 2008

Alcohol linked to increased risk of perennial allergic rhinitis

There is a link between alcohol consumption and increased risk of perennial allergic rhinitis, according to a recent Danish study of 5,870 young adult women.

29 Jul 2008

Lawmakers agree to ban use of phthalates in toys

Lawmakers charged with finalizing the Consumer Product Safety Commission Reform Act agreed yesterday to include a provision that will ban phthalates from children's toys and childcare articles. The legislative action validates the concerns of scientists and parents who have been urging a ban, and will bring federal regulation in line with several states and leading retailers that have already taken action to remove phthalates from toys.

29 Jul 2008

FDA approves first generic divalproex sodium for the treatment of seizures, bipolar disorder and migraine headaches

The U.S. Food and Drug Administration today approved the first generic versions of Depakote delayed-release tablets (divalproex sodium). Depakote is approved by the FDA for the treatment of seizures, bipolar disorder and migraine headaches.

29 Jul 2008