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New report detailing how animal experiments misled scientists on Vioxx

Tommorow, February 17, John J. Pippin, M.D., FA.C.C., will testify before Food and Drug Administration (FDA) officials and present a new report detailing how experiments on mice, dogs, and other animals misled scientists and ultimately contributed to a tragic outcome for human patients exposed to Vioxx and other drugs.

15 Feb 2005

Discovery may have implications for the treatment of hemophilia A and B

University of North Carolina at Chapel Hill researchers have made a discovery that may have implications for the treatment of liver-based genetic defects such as hemophilia A and B in humans.

15 Feb 2005

Dialogue instead of lecture best when advising teens about alcohol

Parents can more effectively advise teens about alcohol and drug use if, first, they try dialogue instead of lecture and, second, they set an everyday example, rather than give the one-time drug sermon, according to a Penn State researcher.

13 Feb 2005

Why estrogenic hormones produce unintended results in women

New research is shedding light on why estrogenic hormones produce unintended results in women, giving hope to the idea that new drugs might reach their targets and work more effectively. Ultimately it could mean that postmenopausal women would know that hormone-replacement therapy would have only its intended result.

13 Feb 2005

Scientists show knocking out key signals will cause diabetes

Using a revolutionary technique to turn off chemical signals inside the cell, scientists at Joslin Diabetes Center have discovered that the different metabolic abnormalities present in type 2 diabetes can be caused by knocking out two key signals in liver cells.

11 Feb 2005

Ximelagatran effective for preventing blood clots and stroke

A medication that could simplify anticoagulation therapy, ximelagatran, was found to be as effective as other common therapies for preventing stroke and recurrent blood clots

9 Feb 2005

Health risks increase in Guyana with leptospirosis

Leptospirosis has become a health concern in Guyana, as the number of cases continues to rise and 43 people were being treated for suspected cases of the bacterial disease, which is usually caused by exposure to water contaminated with the urine of infected animals.

8 Feb 2005

New way to assess the potentially damaging effects of prenatal drug exposure

Scientists have demonstrated a new way to assess the potentially damaging effects of prenatal drug exposure--a technique that could also be used to monitor a fetus's response to therapeutic drugs--using sophisticated, noninvasive medical imaging tools.

7 Feb 2005

Prions, previously thought to accumulate mainly in the brain can also infect other organs

Prions, infectious proteins associated with bovine spongiform encephalopathy (BSE) or Mad Cow Disease, were previously thought to accumulate mainly in the brain, but Yale and University of Zurich researchers report in Science that other organs can also become infected.

7 Feb 2005

Third of cancer patients in Europe make use of complementary and alternative medicine

More than a third of cancer patients in Europe make use of complementary and alternative medicine (CAM), according to one of the largest surveys undertaken of CAM in cancer.

3 Feb 2005

New advice about the use of Strattera (atomoxetine)

New advice to doctors and patients about the use of Strattera, (atomoxetine), was issued today by the Medicines and Healthcare products Regulatory Agency, (MHRA).

3 Feb 2005

Eleventh Edition of the Report on Carcinogens

The Department of Health and Human Services released its Eleventh Edition of the Report on Carcinogens today, adding seventeen substances to the growing list of cancer-causing agents, bringing the total to 246.

31 Jan 2005

Startling results from new biomedical research will smooth path to the market place

Researchers have discovered how to convert liver cells of mice into pancreatic cells using a single injection. This may eventually lead to a cure for diabetes. Dr. James Mittra, one of the organisers of an international conference in Edinburgh on the Evolution of the Life Science Industries asks, “How does the pharmaceutical industry respond to this kind of work? They are primarily interested in treatments, not cures. Do they see this kind of research as a threat?”

27 Jan 2005

The role body fat plays in determining one's risk of chronic diseases

As the prevalence of obesity in America approaches epidemic proportions, researchers are scrambling to learn more about how the body stores fat, how fat tissues affect body systems and the role body fat plays in determining one's risk of chronic diseases.

27 Jan 2005

VCU Gastroenterology research papers ranked 4th in most cited papers

Virginia Commonwealth University’s School of Medicine has been ranked fourth among federally funded U.S. universities based on the average number of citations per research paper published in indexed journals of gastroenterology and hepatology between 1999 and 2003.

26 Jan 2005

Painful surgical adhesions may be preventable by taking the COX-2 inhibitor Celebrex

Adhesions – bands of scar tissue that bind together two internal body surfaces – develop in 55 percent to more than 90 percent of patients undergoing surgery, depending on the type of operation. They are part of normal healing, but when surfaces fuse together that shouldn't, serious pain and complications can result.

26 Jan 2005

Local environment directly influences adult stem cell reservoirs

Using the common fruit fly, researchers at UT Southwestern Medical Center have discovered that an intricate set of signals released by stem cells' surroundings governs their maintenance.

26 Jan 2005

Priming embryonic stem cells to fulfill their promise

Bioengineering researchers at the University of California, San Diego have invented a process to help turn embryonic stem cells into the types of specialized cells being sought as possible treatments for dozens of human diseases and health conditions.

24 Jan 2005

Annual mammograms best for women who have been treated for early stage breast cancer

Annual mammograms and doctor visits are the best follow-up strategy for women who have been treated for early stage breast cancer, according to a new review of recent research.

24 Jan 2005

Severity of liver disease not a reliable indicator of quality of life

A new study on the determination of how livers are allocated for transplants examined the relationship between liver disease severity and quality of life, and found that the commonly used model for liver allocation is not a reliable indicator of general quality of life.

24 Jan 2005