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Significant advance in the understanding of the hepatitis C virus (HCV)

Researchers have made a significant advance in the understanding of the hepatitis C virus (HCV) by identifying new genetic factors associated with clearing the virus spontaneously without the necessity for additional treatment.

9 Aug 2004

Correlation between HCV viral load and severity of liver disease

The significance of hepatitis C virus (HCV) serum titers (HCV viral load) has been examined in several clinical situations. There is much evidence that patients with a lower viral load have better response rates to anti-viral therapy compared to those with higher levels.

9 Aug 2004

Self-recovery from Hep C infection linked to genes that suppress action of killer immune cells

In a study to be published in Science online Aug. 6, researchers at Johns Hopkins have found that genes involved in suppressing the body's defensive "killer" immune cells are a potential key factor in spontaneous recovery from hepatitis C.

5 Aug 2004

PET is a more accurate way to diagnose recurrent melanoma than the present, standard procedures

A new study using positron emission tomography (PET) determined PET is a more accurate way to diagnose recurrent melanoma than the present, standard procedures.

5 Aug 2004

Mefloquine, an anti-malarial drug plays a critical role in movement, vision and memory

Brown University researchers have discovered that mefloquine, an anti-malarial drug, blocks two gap junction proteins, or connexins, in low doses and with very few side effects in the brains of laboratory mice.

5 Aug 2004

Metabasis Therapeutics announces multi-center Phase 2 study to evaluate the orally administered antiviral compound remofovir mesylate

Metabasis Therapeutics has announced the initiation of a multi-center, multi- national Phase 2 study to evaluate the orally administered antiviral compound remofovir mesylate in chronic hepatitis B (HBV) infected patients.

3 Aug 2004

Smart gene therapy might effectively prevent the organ damage commonly suffered by heart attack victims

Early intervention with a novel kind of "smart gene therapy" might effectively prevent the organ damage commonly suffered by heart attack victims, suggests a new animal study by researchers at Brigham and Women's Hospital in Boston and Duke University Medical Center.

2 Aug 2004

Researchers have secured more than $19.4 million for their work on cardiovascular and liver diseases and HIV/AIDS

Sydney University medical researchers have secured more than $19.4 million for their work on cardiovascular and liver diseases and HIV/AIDS in the latest round of National Health and Medical Research Council program grants.

2 Aug 2004

Scientists create mice that don't gain weight, even when fed fat-laden, high calorie diets

By altering the expression of a single -- albeit different – gene, Drs. Roger Davis (UMASS Medical School, USA) and Ying-Hue Lee (Academia Sinica, Taiwan) have succeeded in creating two different strains of transgenic mice that don't gain weight, even when fed fat-laden, high calorie diets.

2 Aug 2004

Alimta receives positive endorsement for lung cancer approval from FDA Advisory Committee

Eli Lilly and Company have announced that the Oncologic Drugs Advisory Committee (ODAC) of the U.S. Food and Drug Administration positively endorsed Alimta® (pemetrexed), an antifolate, for accelerated approval in the second-line treatment of non-small cell lung cancer.

29 Jul 2004

Study shows safe, effective therapy for previously untreated patients with HIV & hepatitis C

An international study with nearly 900 patients co-infected with Human Immunodeficiency Virus (HIV) and hepatitis C virus (HCV) has shown that HCV can be treated effectively and safely, without compromising the patient’s HIV therapy.

29 Jul 2004

New drug combination more effective than the previous generation of hepatitis C/HIV therapy

A new study reveals the highest efficacy rates ever reported among patients co-infected with hepatitis C and HIV treated with pegylated interferon and ribavirin.

28 Jul 2004

FDA approval for VYTORIN for the treatment of high LDL cholesterol (LDL-C)

Merck/Schering-Plough Pharmaceuticals has announced that the U.S. Food and Drug Administration has approved VYTORIN™ (ezetimibe/simvastatin) for the treatment of high LDL cholesterol (LDL-C) in patients with primary hypercholesterolemia or mixed hyperlipidemia as adjunctive therapy to diet when diet alone is not enough.

26 Jul 2004

Bladder-sparing treatment shows promise against cancer

For patients with invasive bladder cancer, treatment has typically meant an operation to remove the bladder and nearby organs. This requires up to a week in the hospital and leaves patients with a reconstructed bladder or urostomy bag.

21 Jul 2004

Illinois bill that allows people with HIV to donate organs to other people who are HIV-positive

The bill was written by state representative Larry McKeon, who has HIV, and signed by Governor Rod R. Blagojevich. In the past, people with HIV were not considered good candidates for transplantation because of a reduced life expectancy. Drug treatments are now more advanced, and people with HIV are living longer.

21 Jul 2004

Liver News and Research

Significant advance in the understanding of the hepatitis C virus (HCV)

Correlation between HCV viral load and severity of liver disease

Self-recovery from Hep C infection linked to genes that suppress action of killer immune cells

PET is a more accurate way to diagnose recurrent melanoma than the present, standard procedures

Mefloquine, an anti-malarial drug plays a critical role in movement, vision and memory

Metabasis Therapeutics announces multi-center Phase 2 study to evaluate the orally administered antiviral compound remofovir mesylate

Smart gene therapy might effectively prevent the organ damage commonly suffered by heart attack victims

Researchers have secured more than $19.4 million for their work on cardiovascular and liver diseases and HIV/AIDS

Scientists create mice that don't gain weight, even when fed fat-laden, high calorie diets

Alimta receives positive endorsement for lung cancer approval from FDA Advisory Committee

Study shows safe, effective therapy for previously untreated patients with HIV & hepatitis C

New drug combination more effective than the previous generation of hepatitis C/HIV therapy

FDA approval for VYTORIN for the treatment of high LDL cholesterol (LDL-C)

Bladder-sparing treatment shows promise against cancer

Illinois bill that allows people with HIV to donate organs to other people who are HIV-positive

Roche files for application with FDA to market hepatitis C medication Pegasys(R) for chronic hepatitis B treatment

Debate over acetaminophen and acute liver failure

Blacks receive transplants at disproportionately low rates

Research provides new insight into the carefully controlled architectural changes that underlie organ development

Hospitals are being urged to address the alcohol problems that afflict up to 30 per cent of men and 15 per cent of women

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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