Lobular Breast Cancer News and Research

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Multi-center analysis shines light on invasive lobular carcinoma

A multi-center analysis of patients with invasive lobular carcinoma, or ILC -; the second most common histological subtype of invasive breast cancer in the U.S. -; showed that, despite its prevalence, ILC is detected later and has worse outcomes than the predominant subtype of invasive breast cancer, known as invasive ductal carcinoma (IDC), or no special type.

14 Oct 2022

Study finds a more effective treatment option for HER2 mutant metastatic breast cancer

Breast cancers with HER2 mutations respond to the drug neratinib, but the responses are variable and often not durable.

23 Jun 2022

How new Insights into ESR1 Mutant Breast Cancers may lead to Novel Therapy Targets

In this interview, we speak to Steffi Oesterreich, PH.D., from the University of Pittsburgh, about how new insights into a gene mutation present in 20-30% of breast cancer recurrences may have a silver lining, leading to novel treatment opportunities.

9 May 2022

Xenograft model for invasive lobular carcinoma simulates tumor with high accuracy

Invasive lobular carcinoma (ILC) is a type of breast cancer that begins in the milk-producing glands (lobules) of the breast.

22 Feb 2021

Genetic testing results help woman to make decisions about her treatment and preventive care

Wendy Richardson, 52, of Ridgefield, Connecticut, has always been aware that she has a strong family history of cancer.

3 Dec 2019

New diagnostic test could end unnecessary chemotherapy for breast cancer

A diagnostic test developed at The University of Queensland might soon determine if a breast cancer patient requires chemotherapy or would receive no benefit from this gruelling treatment.

29 Jun 2019

AeroForm Tissue Expanders makes breast reconstruction after mastectomy more comfortable

Henry Ford Cancer Institute is the first in Michigan to offer a needle-free, patient-controlled tissue expansion system for women undergoing breast reconstruction after mastectomy.

20 Mar 2019

Researchers reveal new subtypes of invasive lobular carcinoma

Researchers from the UNC Lineberger Comprehensive Cancer Center and other academic centers have revealed new subtypes of invasive lobular carcinoma, the second most commonly diagnosed invasive breast cancer type. The findings could lead to personalized treatment approaches for the disease.

9 Oct 2015

Existing drugs could help prevent deadly familial stomach and lobular breast cancers

Deadly familial stomach and lobular breast cancers could be successfully treated at their earliest stages, or even prevented, by existing drugs that have been newly identified by cancer genetics researchers at New Zealand's University of Otago.

23 Mar 2015

Prolonged use of calcium-channel blocker to treat BP linked with high breast cancer risk

Long-term use of a calcium-channel blocker to treat hypertension (high blood pressure) is associated with higher breast cancer risk, according to a report published by JAMA Internal Medicine, a JAMA Network publication.

6 Aug 2013

Genetic, lifestyle factors and HRT increase risk of breast cancer

The risk of breast cancer is increased by genetic and lifestyle factors such as the inherited BRCA2 gene, age of having first child, or use of hormone replacement therapy (HRT).

28 Nov 2011

Neoadjuvant chemotherapy prior to surgery can benefit women with lobular breast cancer

Researchers at the Medical University of Vienna have found that the breast of one in two women with lobular breast cancer can be preserved through chemotherapy prior to a breast operation.

26 Aug 2011

BC Cancer Agency scientists find major breakthrough in breast cancer

For the first time in history, BC Cancer Agency scientists in British Columbia, Canada have decoded all of the three billion letters in the DNA sequence of a metastatic lobular breast cancer tumour, a type of breast cancer which accounts for about 10 per cent of all breast cancers, and have found all of the mutations, or "spelling" mistakes that caused the cancer to spread.

8 Oct 2009

Statins may be useful in patients with tamoxifen-resistant breast cancer

Breast cancer cells in the laboratory that don't respond to tamoxifen may be producing high amounts of cholesterol in order to provide a kind of shield against the drug, say researchers at Georgetown University Medical Center (GUMC).

20 Apr 2009

Study identifies potential 'safe period' for hormone replacement use

A new study makes important new findings on the role of hormone use on the risk of breast cancer, confirming that the use of estrogen plus progesterone increases the risk of both ductal and lobular breast cancer far more than estrogen-only; suggesting a two-year 'safe' period for the use of estrogen and progesterone; and finding that the increased risk for ductal cancers observed in long-term past users of hormone replacement therapy drops off substantially two years after hormone use is stopped.

2 Feb 2009

The link between combined HRT use and the risk of lobular breast cancers

Postmenopausal women who take combined estrogen/progestin hormone-replacement therapy for three years or more face a fourfold increased risk of developing various forms of lobular breast cancer, according to new findings by researchers at Fred Hutchinson Cancer Research Center.

15 Jan 2008

Lobular Breast Cancer News and Research

Multi-center analysis shines light on invasive lobular carcinoma

Study finds a more effective treatment option for HER2 mutant metastatic breast cancer

How new Insights into ESR1 Mutant Breast Cancers may lead to Novel Therapy Targets

Xenograft model for invasive lobular carcinoma simulates tumor with high accuracy

Genetic testing results help woman to make decisions about her treatment and preventive care

New diagnostic test could end unnecessary chemotherapy for breast cancer

AeroForm Tissue Expanders makes breast reconstruction after mastectomy more comfortable

Researchers reveal new subtypes of invasive lobular carcinoma

Existing drugs could help prevent deadly familial stomach and lobular breast cancers

Prolonged use of calcium-channel blocker to treat BP linked with high breast cancer risk

Genetic, lifestyle factors and HRT increase risk of breast cancer

Neoadjuvant chemotherapy prior to surgery can benefit women with lobular breast cancer

BC Cancer Agency scientists find major breakthrough in breast cancer

Statins may be useful in patients with tamoxifen-resistant breast cancer

Study identifies potential 'safe period' for hormone replacement use

The link between combined HRT use and the risk of lobular breast cancers

Researchers identify novel genetic mutations linked to hereditary diffuse gastric cancer

Woman awarded millions in Prempro HRT breast cancer trial

Selecting patients for breast conserving therapy: The importance of lobular histology

Somatic adult stem cell niches - key regulators of stem cell activity in mammary tissue

Speeding Up Sample Preparation to Accelerate Analytical Chemistry

Ask the Expert: 7 Questions about Colorectal Cancer & Non-invasive Fecal DNA Testing

Snapping at new biotech breakthroughs with Gator Pro

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