Low Density Lipoprotein (LDL) News and Research

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Data expands the clinical utility of deCODE tests for heart attack, atrial fibrillation and stroke

Several presentations by deCODE genetics scientists and independent researchers at the American Heart Association Scientific Sessions 2008 being held at the New Orleans Convention Center from November 8 to12 are expected to expand upon the clinical utility of evaluating individual risk of heart attack, or atrial fibrillation and stroke, respectively, by measuring the genetic markers that are the basis of the deCODE MI and deCODE AF tests.

11 Nov 2008

New risk factor for heart disease suggests more should be on statins

Canadian scientists have discovered a new risk factor for cardiovascular disease and the significance of their discovery was so conclusive that the clinical trial was stopped before its scheduled completion date.New risk factor for heart disease suggests more should be on statins

10 Nov 2008

High levels of high-sensitivity C-reactive protein found to be new risk factor for cardiovascular disease

A team of international researchers - including scientists from the McGill University Health Centre (MUHC) and McGill University - have discovered that having high levels of particular protein puts patients at increased risk of developing cardiovascular disease.

10 Nov 2008

Rising triglyceride levels may be behind rising rates of obesity

A new 30-year analysis of the National Health and Nutrition Examination Survey (NHANES) database conducted by the National Lipid Association (NLA) indicates that while Americans are doing a better job of managing LDL or "bad" cholesterol, the percentage of adults with high triglycerides, a blood fat linked to heart disease, has doubled, leaving many people at risk for potentially life-threatening events such as heart attack or stroke.

10 Nov 2008

Crestor (rosuvastatin calcium) shown to significantly reduce major cardiovascular events

New data from the JUPITER study demonstrated that Crestor (rosuvastatin calcium) 20 mg significantly reduced major cardiovascular (CV) events (defined in this study as the combined risk of myocardial infarction, stroke, arterial revascularization, hospitalization for unstable angina, or death from CV causes) by a dramatic 44% compared to placebo (p<0.001) among men and women with elevated hsCRP but low to normal cholesterol levels.

10 Nov 2008

Obese teenagers face higher metabolic syndrome risk in South America than Europe

Obese teenagers are much more likely to suffer from metabolic syndrome - which can lead to heart disease - if they live in Brazil than Italy, according to a study in the October issue of IJCP, the International Journal of Clinical Practice.

13 Oct 2008

Corgenix receives third U.S. patent on AtherOx technology

Corgenix Medical Corporation has received notification of U.S. Patent Office approval for technology to which Corgenix holds exclusive worldwide licensing rights outside of Japan.

25 Sep 2008

The effects of A2 inhibitor Darapladib on human coronary athlerosclerotic plaque

A twelve month study of treatment with darapladib concluded that,Lp-PLA2 inhibition with darapladib prevented necrotic core expansion, a key determinant of plaque vulnerability.

2 Sep 2008

Results from the Simvastatin and Ezetimibe in aortic stenosis study

The SEAS (Simvastatin and Ezetimibe in Aortic Stenosis) study has investigated the effects of intensive cholesterol lowering with the combination of simvastatin (40 mg daily) and ezetimibe (10 mg daily) in patients with aortic stenosis.

2 Sep 2008

Save your life by taking the stairs instead of the lift

Researchers say walking up the stairs at work instead of taking the lift could be a lifesaver.

1 Sep 2008

Sex hormones link to heart risk

Men are more prone to - and likely to die of - heart disease compared with women of a similar age - and sex hormones are to blame, according to a new University of Leicester led study.

1 Sep 2008

Issues on cholesterol: diet, statins and genetics

Genetic lipoprotein disorders are frequently seen in patients with premature coronary artery disease (CAD). An example of strong genetic predisposition is the disorder: familial hypercholesterolemia, where a single gene defect (the low density lipoprotein receptor) contributes to most of the familial expression of CAD.

1 Sep 2008

High cholesterol levels drop naturally in children on high-fat antiseizure diet

Elevated cholesterol levels return to normal or near normal levels over time in four out of 10 children with uncontrollable epilepsy treated with the high-fat ketogenic diet, according to results of a Johns Hopkins Children's Center study reported in the Journal of Child Neurology.

26 Aug 2008

Designer RNA fights high cholesterol, medical researchers find

Small, specially designed bits of ribonucleic acid (RNA) can interfere with cholesterol metabolism, reducing harmful cholesterol by two-thirds in pre-clinical tests, according to a new study by researchers at UT Southwestern Medical Center in collaboration with Alnylam Pharmaceuticals and the Massachusetts Institute of Technology.

11 Aug 2008

Consumer group says finding healthy food for children in fast food restaurants is tough

A consumer watchdog group in the United States says when it comes to fast food restaurants, it is a struggle to find anything remotely healthy for a child to eat.

5 Aug 2008

Newly identified risk factor for cardiovascular disease may lead to new treatments

Low levels of naturally occurring antibodies may represent an increased risk of developing cardiovascular disease, particularly stroke in men. This discovery, published in the academic journal Atherosclerosis, has now led to attempts to develop an immunization against cardiovascular disease.

31 Jul 2008

Low Density Lipoprotein (LDL) News and Research

Data expands the clinical utility of deCODE tests for heart attack, atrial fibrillation and stroke

New risk factor for heart disease suggests more should be on statins

High levels of high-sensitivity C-reactive protein found to be new risk factor for cardiovascular disease

Rising triglyceride levels may be behind rising rates of obesity

Crestor (rosuvastatin calcium) shown to significantly reduce major cardiovascular events

Obese teenagers face higher metabolic syndrome risk in South America than Europe

Corgenix receives third U.S. patent on AtherOx technology

The effects of A2 inhibitor Darapladib on human coronary athlerosclerotic plaque

Results from the Simvastatin and Ezetimibe in aortic stenosis study

Save your life by taking the stairs instead of the lift

Sex hormones link to heart risk

Issues on cholesterol: diet, statins and genetics

High cholesterol levels drop naturally in children on high-fat antiseizure diet

Designer RNA fights high cholesterol, medical researchers find

Consumer group says finding healthy food for children in fast food restaurants is tough

Newly identified risk factor for cardiovascular disease may lead to new treatments

Statins reduce the risk of dementia by half

More research needed into effects of flavonoids and flavonoid-rich food sources on heart disease

Combining medical knowledge to save lives

Low levels of good cholesterol could signal dementia

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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