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Stapled lipopeptides show promise as broad-spectrum antiviral agents

Compounds that obstruct the "landing gear" of a range of harmful viruses can successfully protect against infection by the virus that causes COVID-19, a study published today and led by Dana-Farber Cancer Institute scientists shows.

5 Jan 2024

New study brings us closer to growing replacement lungs for patients

Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide. It is marked by lung damage that is lasting and incurable, leaving lung transplantation as the only viable treatment option.

5 Jan 2024

Breakthrough drug halts lung cancer and brain metastases

D'Or Institute for Research and Education (IDOR) played an important role in the phase III LIBRETTO-431 multicenter study, which evaluated the efficacy and safety of selpercatinib compared to control treatment, which consisted of platinum-based chemotherapy associated or not with pembrolizumab (immune checkpoint inhibitor) in non-small cell lung cancer (NSCLC).

5 Jan 2024

Scientists unearth dual-action weapons against deadly tuberculosis

A research team has detected various substances that have a dual effect against tuberculosis: They make the bacteria causing the disease less pathogenic for human immune cells and boost the activity of conventional antibiotics / publication in ‘Cell Chemical Biology’.

4 Jan 2024

Researchers harness the power of AI to enhance assessment of the heart's right ventricle

In a milestone study, researchers from the Icahn School of Medicine at Mount Sinai have harnessed the power of artificial intelligence (AI) to enhance the assessment of the heart's right ventricle, which sends blood to the lungs.

4 Jan 2024

Study identifies mitochondrial dysfunction as cause of long-COVID fatigue

Researchers from Amsterdam UMC and Vrije Universiteit Amsterdam (VU) have discovered that the persistent fatigue in patients with long-COVID has a biological cause, namely mitochondria in muscle cells that produce less energy than in healthy patients.

4 Jan 2024

Healthy fats from fish and nuts may slow lung scarring, delay transplants

Could healthy fats found in nuts and fish slow the progression of potentially deadly lung scarring known as pulmonary fibrosis and delay the need for lung transplants?

2 Jan 2024

How immune cells shape our earliest breaths

Study profiles the development of immune cells in human lungs during embryonic and fetal stages, revealing their influence on epithelial cell fate and lung development.

1 Jan 2024

Researchers receive two grants to study tuberculosis drug development

Weill Cornell Medicine researchers and the TB Drug Accelerator have received two grants totaling $6.8 million from the Bill & Melinda Gates Foundation to study tuberculosis (TB) drug development.

26 Dec 2023

Scientists develop a method for tracking cellular events over time in living organisms

While physicists continue to argue about whether time is indeed an illusion, as Albert Einstein claimed, biologists have no doubt about its significance for understanding life as a dynamic system.

21 Dec 2023

Deep flaws in FDA oversight of medical devices, and patient harm, exposed in lawsuits and records

Living with diabetes, Carlton "PeeWee" Gautney Jr. relied on a digital device about the size of a deck of playing cards to pump insulin into his bloodstream.

21 Dec 2023

Daily toothbrushing in hospitals linked to significant drop in pneumonia cases and ICU mortality rates

Study shows that daily toothbrushing significantly reduces the incidence of hospital-acquired pneumonia (HAP), especially in mechanically ventilated patients, leading to shorter ICU stays and lower ICU mortality rates.

19 Dec 2023

Autopsy study provides new insights into yellow fever's impact on the heart

To fill gaps in knowledge of yellow fever (YF), a group of researchers in Brazil affiliated with the Department of Pathology at the University of São Paulo's Medical School (FM-USP), Hospital das Clínicas (HC, the hospital complex run by FM-USP), the Heart Institute (InCor, linked to HC) and Emílio Ribas Institute of Infectious Diseases (IIER) decided to study the pathogenesis of YF-associated heart injury.

19 Dec 2023

New study shows air quality impacts imagination and inventiveness

Air quality in the office may affect our level of creativity at work, scientists at Nanyang Technological University, Singapore (NTU Singapore) have found.

19 Dec 2023

Cinnamon extract shows promise in reducing obesity by inhibiting fat cell growth and boosting fat breakdown

Study reveals that cinnamon extract significantly inhibits adipocyte differentiation and lipid accumulation, offering potential benefits against obesity by reducing fat production and enhancing lipolysis in both cell models and mice.

18 Dec 2023

Daily toothbrushing may lower hospital-acquired pneumonia rates

Researchers have found an inexpensive tool that may help reduce rates of pneumonia for hospitalized patients-;and it comes with bristles on one end.

18 Dec 2023

Study suggests iron accumulation plays a central role in senescence and fibrosis

Researchers investigated the association between cellular damage, iron buildup, senescence, and fibrosis.

18 Dec 2023

Study links omicron's cellular senescence to inflammation and long-COVID risk

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 23, entitled, "Uncovering a unique pathogenic mechanism of SARS-CoV-2 omicron variant: selective induction of cellular senescence."

15 Dec 2023

Study reveals unexpected role of immune cells in early human lung development

Immune cells play an active and intimate role in directing the growth of human lung tissue during development, researchers find, revolutionizing our understanding of early lung development and the role of immune cells outside of immunity.

15 Dec 2023

New dry powder aerosol COVID-19 vaccine shows promise against multiple virus strains

Study introduces a novel dry powder aerosol COVID-19 vaccine, showing its effectiveness in inducing strong immune responses and offering protection against various SARS-CoV-2 strains, including Omicron.

15 Dec 2023