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Medical College of Wisconsin receives grant to study infantile hemangiomas

The Food and Drug Administration (FDA) has awarded the Medical College of Wisconsin in Milwaukee a three-year, $1 million Orphan Products Development grant to study infantile hemangiomas – a vascular tumor of the skin or internal organs.

25 Oct 2007

Combination targets offer new hope in fight against cancer

While some targeted therapies - drugs developed to attack specific molecules in the critical chemical pathways occurring within cancer cells - work well by themselves, increasingly researchers are finding that they work better when teamed with other targeted and conventional therapies.

24 Oct 2007

Children may be particularly susceptible to avian influenza

New findings, reported in in the online open access journal Respiratory Research, about how the virus binds to the respiratory tract and lung suggest children may be particularly susceptible to avian influenza.

24 Oct 2007

Alcoholism in the family linked to greater sweet preferences among women

More than 250 million women worldwide smoke tobacco. Compared to men, women have a greater risk of smoking-related diseases, and also have more difficulty quitting. A new study, the first of its kind, has found that cigarette smoking and having a family history of alcoholism have different effects on sweet-taste perception and food cravings.

24 Oct 2007

Potent inhibitor of Kinesin CENP-E demonstrates tumor cell inhibition

A first-in-class, targeted investigational therapy specifically designed to inhibit a single protein that functions only during cell division shows potent activity in a broad range of cancer cell lines, say researchers from GlaxoSmithKline.

24 Oct 2007

Experimental cancer pharmaceuticals under trial

A potent and selective inhibitor of the mitotic kinesin CENP-E (GSK923295A) demonstrates a novel mechanism of inhibiting tumor cell proliferation and shows activity against a broad panel of human tumor cell lines in vitro: Abstract A 111.

24 Oct 2007

Advances in drug screening

With the discovery of suitable molecular targets - cellular molecules along pathways crucial for sustaining the life of cancer cells - comes the perplexing dilemma of where to find the next therapeutics that will bind to and disable those targets.

23 Oct 2007

Cellular power plant fault explains abnormal metabolism of tumours

The increased consumption of glucose that tumour cells exhibit, was thought to be a cause of the extra demand of building blocks required to keep up with an uncontrolled cell growth, but now it is more accepted that it could be the effect of a programmed metabolic change that favours this malignant growth.

23 Oct 2007

One out of three patients with asthma or COPD use inhalers incorrectly

One out of three patients with asthma or chronic obstructive pulmonary disease (COPD) use their inhalers incorrectly, a new study shows.

23 Oct 2007

Simple test reveals smokers who are less than honest

Smokers who lie about their habit to their doctors could in future be caught out by a simple blood test.

23 Oct 2007

Spending more for lung cancer treatment did not substantially increase patients' lives

A new study finds that survival for elderly patients with lung cancer has changed little despite large increases in healthcare expenditures for lung cancer treatment.

22 Oct 2007

Endobronchial valve improves quality of life in emphysema patients

Emphysema patients whose lungs are implanted with a pencil eraser-sized, one-way endobronchial valve experience significantly improved measures of lung function and report better quality of life, University of Pittsburgh School of Medicine researcher Frank C. Sciurba, M.D., reported today at CHEST 2007, the annual meeting of the American College of Chest Physicians.

22 Oct 2007

Smoking cessation programs should be tailored to age

A new study shows that obstacles to smoking cessation and motives for quitting smoking vary with age.

22 Oct 2007

Discovery of two genes linked to a disabling form of arthritis called ankylosing spondylitis

An international team of researchers led by a Fred Hutchinson Cancer Research Center geneticist has discovered two genes linked to a disabling form of arthritis called ankylosing spondylitis, a painful and progressive disease in which some or all of the spine's vertebrae fuse together.

22 Oct 2007

Canada leads in new heart valve replacement surgery

Canada is the world leader in a new surgical technique that is transforming the lives of patients too sick to undergo conventional treatment to replace diseased aortic valves.

22 Oct 2007

New links in the cystic fibrosis chain uncover potential therapeutics

Cystic fibrosis (CF) is an inherited disease caused by mutations in the CFTR gene.

19 Oct 2007

Avastin and chemo combo may offer hope for glioblastoma multiforme patients

Brain cancer patients with the poorest prognosis -- those with a type of deadly tumor known as glioblastoma multiforme (GBM) -- may survive longer with a drug that chokes off a tumor's blood supply.

19 Oct 2007

Accelr8 announces patent allowance for rapid bacterial diagnostic method

Accelr8 Technology Corporation has announced that it received notice of allowance on the first patent related to its BACcel rapid diagnostic platform.

19 Oct 2007

MRSA superbug a bigger killer than AIDS

The Centers for Disease Control (CDC) in the United States says MRSA infections (methicillin-resistant Staphylococcus aureus) are more prevalent and invasive than previously thought.

18 Oct 2007

New model helps explain rules governing the transmission of microbes

Many of the most successful microbes are those that inhabit but do not kill their host. Cheaters lose. Tuberculosis settles into the lungs. Helicobacter pylori, the microbe causing ulcers, burrows into the stomach where it thrives on acids. And Salmonella typhi takes up residence in the gallbladder. All of these organisms can persist in our bodies for decades. What explains their success?

18 Oct 2007