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Rheumatoid arthritis linked to excess risk of congestive heart failure

A serious chronic disease, rheumatoid arthritis (RA) is characterized by inflammation and damage of the joint, major organ involvement and increased mortality. Among patients, about one in three deaths results from cardiovascular disease (conditions affecting the heart or blood vessels).

3 Feb 2005

Eleventh Edition of the Report on Carcinogens

The Department of Health and Human Services released its Eleventh Edition of the Report on Carcinogens today, adding seventeen substances to the growing list of cancer-causing agents, bringing the total to 246.

31 Jan 2005

Nicotine may hold promise in the early diagnosis of Alzheimer's disease

The chemical nicotine--a main ingredient in tobacco--may hold promise in the early diagnosis of Alzheimer's disease, give insight into therapeutic interventions for nicotine addiction and possibly complement the diagnosis of certain forms of lung cancer, according to a study in the January issue of the Society of Nuclear Medicine's Journal of Nuclear Medicine.

31 Jan 2005

$Screening for osteoporosis in men and women age 65 and older can prevent a large number of hip fractures$

Screening for osteoporosis in men and women age 65 and older can prevent a large number of hip fractures

Researchers at Johns Hopkins have determined that screening for osteoporosis in men and women age 65 and older can prevent a large number of hip fractures, a debilitating, traumatic experience for 340,000 older adults annually.

31 Jan 2005

No association between a herpesvirus infection and pulmonary hypertension

Contrary to the results of a recent U.S. study, investigators in Japan found no association between a herpesvirus infection and a potentially life-threatening form of high blood pressure, as reported in the March 1 issue of The Journal of Infectious Diseases, now available online.

30 Jan 2005

Passive smoking increases likelihood of lung cancer in children later in life

Children who are exposed to environmental tobacco smoke (passive smoking) are at a higher risk of developing lung cancer as adults, says a paper in this week's BMJ.

30 Jan 2005

Physical traits, genetic test help with early diagnosis of aneurysm syndrome

A research team led by Johns Hopkins doctors has defined the physical traits and genetic basis of a new aortic aneurysm syndrome that is extremely aggressive and can cause death in early childhood. Early diagnosis of the syndrome and rapid surgical repair of the swollen aorta can save lives, the researchers report in the Jan. 30 advance online section of Nature Genetics.

30 Jan 2005

Clinical trials to test the safety of a first-of-its-kind human hookworm vaccine

Clinical trials to test the safety of a first-of-its-kind human hookworm vaccine will begin in the Washington, DC area in a couple of months after the U.S. Food and Drug Administration conferred investigational new drug status on the vaccine.

27 Jan 2005

Trial of Etanercept for Wegners's disease shows no benefit against the autoimmune condition

A Johns Hopkins-led study designed to evaluate the ability of etanercept to maintain disease remissions in a serious autoimmune disorder has failed to show any benefit. Etanercept, also called Enbrel, is a common treatment for rheumatoid arthritis and other types of joint inflammation.

26 Jan 2005

Why some men develop aggressive prostate cancer that becomes resistant to hormone-withdrawal therapy

Researchers found that certain mutations in a protein called the androgen receptor cause advanced and invasive prostate cancer when put into otherwise healthy mice. The androgen receptor's normal function is to control growth of the prostate gland in response to cues from male hormones called androgens, which have long been thought to stimulate prostate tumors.

26 Jan 2005

Blood clots in the lungs could be prevented with computed tomography (CT) scans of the legs

Researchers found that indirect CT venography (CTV) could identify blood clots in the legs that have the potential to break free, travel to the lung and block an artery--a life-threatening condition known as pulmonary embolism.

25 Jan 2005

High blood pressure risk in African-Americans linked to genetics

National health records have shown that African-Americans are more prone to high blood pressure than Caucasians, but pinning down the roots of that difference has proven elusive. Now, researchers at the Stanford University School of Medicine have narrowed down the search for genes that contribute to this difference in disease risk.

24 Jan 2005

Screening tests find colorectal cancer in its earliest stages when it can be treated more successfully

Colorectal cancer (CRC) is second only to lung cancer as the leading cause of cancer-related death in the United States. In 2004, it’s estimated that CRC caused nearly 57,000 deaths.

18 Jan 2005

Broadening treatment to battle recurrence of endometrial cancer

Mayo Clinic researchers studying endometrial cancer have found that patients at risk for relapse based on identified risk factors had a 46 percent probability of experiencing recurrence within five years despite treatment with state-of-the-art therapy.

18 Jan 2005