Lupus Erythematosus News and Research

RSS

Rituximab reduces kidney inflammation in patients with severe lupus nephritis

Treatment with the targeted drug rituximab can significantly benefit some patients with severe lupus nephritis who do not respond to conventional therapy, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN).

4 Mar 2009

Scientists discover key protein component involved in inflammation

Reporting in the journal Nature, researchers led by Emad Alnemri, Ph.D., professor of Biochemistry and Molecular Biology in the Kimmel Cancer Center at Jefferson, discovered a key protein component involved in inflammation.

23 Jan 2009

Discovery of key protein regulator of inflammation and cell death

Reporting in the journal Nature , researchers led by Emad Alnemri, Ph.D., professor of Biochemistry and Molecular Biology in the Kimmel Cancer Center at Jefferson, discovered a key protein component involved in inflammation.

23 Jan 2009

Blocked Interleukin 21 protein prevents Lupus in mouse model

Mice from a strain that ordinarily develops systemic lupus erythematosus (SLE), but bred with a deficiency in receptor for the protein Interleukin 21, stayed healthy and exhibited none of the symptoms of the disease, researchers at The Jackson Laboratory and National Institutes of Health report.

21 Jan 2009

Corgenix receives third U.S. patent on AtherOx technology

Corgenix Medical Corporation has received notification of U.S. Patent Office approval for technology to which Corgenix holds exclusive worldwide licensing rights outside of Japan.

25 Sep 2008

Lupus more severe in patients with ancestry from southern Europe

Systemic lupus erythematosus (SLE) patients with a higher percentage of ancestry from southern Europe have more severe disease manifestations, according to new research presented today at EULAR 2008, the Annual Congress of the European League Against Rheumatism in Paris, France.

11 Jun 2008

Abnormal "editing" of gene messages may cause Lupus

Researchers at Wake Forest University have uncovered evidence that the abnormal "editing" of gene messages in a type of white blood cell may be behind the development of lupus. Scientists hope the finding will lead to earlier diagnosis, a way to monitor patients' response to therapy and possibly a new way to treat the disease.

19 May 2008

Methamphetamine use and pulmonary arterial hypertension

The Pulmonary Hypertension Association (PHA), in conjunction with leading pulmonary hypertension specialists, has announced the launch of an educational campaign to raise awareness of the association between pulmonary arterial hypertension (PAH) and stimulant use, particularly methamphetamine use.

24 Mar 2008

Genetics behind the disease systemic lupus erythematosus almost completed

A new study has mapped the risk factors behind the autoimmune disease SLE in the entire human genome.

22 Jan 2008

International team pinpoints the genes for lupus

An international team of researchers has pinpointed the genes involved in the auto-immune system disease lupus.

21 Jan 2008

Discovery of multiple genes linked to systemic lupus erythematosus

A landmark genetic study has identified multiple genes linked to systemic lupus erythematosus (SLE), or lupus, a debilitating autoimmune disease that affects an estimated 1.4 million Americans.

21 Jan 2008

Common variations in human DNA signal lupus risk

Scientists have pinpointed a set of common variations in human DNA that signal a higher risk for lupus in women who carry them.

21 Jan 2008

Researchers associate six new genetic variants with heart disease risk factor

Using new techniques for rapidly scanning the human genome, researchers have associated levels of cholesterol and triglycerides, two fats in the blood, to 18 genetic variants, six of which represent new DNA regions never before associated with the traits.

15 Jan 2008

Growing burden of arthritis in the U.S.

Arthritis is the most common cause of disability in the United States. Over the next 25 years as the Baby Boom generation continues to age, the toll of this disease will escalate.

3 Jan 2008

UT Southwestern secures $5 million grant for lupus research

The division of rheumatic diseases in the Department of Internal Medicine at UT Southwestern Medical Center has been awarded a five-year, $5 million grant from the National Institutes of Health to fund the Center of Research Translation, which will investigate the autoimmune disease systemic lupus erythematosus (SLE).

20 Dec 2007

Discovery of key lupus gene

Wellcome Trust researchers have identified a key gene involved in the disease Lupus, which affects around 50,000 people in the UK, mostly women.

3 Dec 2007

Mycophenolate mofetil therapy effective for reducing lupus flares

Mayo Clinic researchers have shown that an immunosuppressive drug used in organ transplant cases is effective in reducing flare-ups in patients with systemic lupus erythematosus (SLE)

13 Nov 2007

Human Genome Sciences announces positive phase 2 LymphoStat-B results

Human Genome Sciences, Inc. has announced the presentation of Phase 2 clinical results demonstrating that LymphoStat-B (belimumab) achieved a sustained improvement in disease activity across multiple clinical measures, decreased the frequency of disease flares over time, and was well tolerated through 2.5 years on treatment in combination with standard of care in patients with active systemic lupus erythematosus (SLE).

13 Nov 2007

Extensive review supports safety of silicone breast implants

An exhaustive review - the first in almost a decade, including the latest evidence on the health effects of silicone breast implants - finds no increase in the risk of cancers, connective tissue diseases, or other serious chronic diseases.

28 Oct 2007

Dermatology's role in advancing the science of wound care

Cosmetic, medical and surgical dermatologists all play a role in the treatment and management of wounds, according to an editorial in the October issue of Archives of Dermatology, a theme issue on wound healing.

16 Oct 2007