Lynch Syndrome News and Research

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Exercise boosts immune defense in Lynch syndrome patients

Aerobic exercise, specifically cycling, shows promise in reducing inflammation and boosting immune responses in the colonic tissue of Lynch syndrome patients, a group at high risk for colorectal cancer. The study suggests that regular exercise may offer a preventive approach for this patient population, though further randomized trials are needed.

24 Sep 2023

High-intensity exercise may reduce colorectal cancer risk in Lynch Syndrome patients

Regular and intense aerobic exercise may reduce the risk of colorectal cancer in patients with Lynch Syndrome (LS) by improving the immune system's ability to detect and remove potentially harmful cells, according to researchers at The University of Texas MD Anderson Cancer Center.

19 Sep 2023

Many patients with Lynch syndrome remain undiagnosed, study finds

New research from Cedars-Sinai Cancer investigators could warrant reconsideration of current screening guidelines to include a poorly recognized cause of Lynch syndrome, the most common cause of hereditary colorectal and endometrial cancers.

11 Jul 2023

Adopting a 30th birthday genetic profile test could save lives and NHS costs

A new study published in the US medical journal ‘The Annals of Internal Medicine’ makes a very strong case for universal genetic testing at the age of 30.

24 Jun 2023

What was the prevalence of germline genetic testing among patients diagnosed with cancer in California and Georgia between 2013 and 2019?

Researchers performed an observational study to determine the prevalence of germline genetic testing among all patients aged 20 years or older diagnosed with cancer between January 1, 2013, and March 31, 2019, in two United States, California and Georgia.

8 Jun 2023

Study reports cost-effectiveness of population genetic testing

An exhaustive cost-benefit analysis of population genetic testing published in Annals of Internal Medicine concludes with a recommendation to U.S. health policymakers to adopt routine testing of adults ages 40 and under for three genetic conditions posing high risk of life-threatening illness.

9 May 2023

Point-of-care testing can be effective for improving access to cancer genetic services

Genetic testing for hereditary cancers, such as breast, colon, pancreatic, and ovarian cancer, helps at-risk individuals understand their familial risk for these diseases and make informed decisions about next steps in care.

5 May 2023

Why are colon cancer rates in young people rising?

In a recent perspective article published in the journal Science, researchers at the Young-Onset Colorectal Cancer Center of Dana-Farber Cancer Institute emphasized that a better understanding of the etiology of early-onset colorectal cancer (EOCRC) is crucial to managing its increasing incidence worldwide

21 Mar 2023

An expert from Yale Cancer Center discusses colorectal cancer among young people, screening guidelines, and more

Michael Cecchini, MD, Yale Cancer Center medical oncologist specializing in gastrointestinal cancers, is available to discuss several topics during colorectal cancer awareness month.

2 Mar 2023

AI can improve the effectiveness of colonoscopy in the presence of Lynch syndrome

First study of AI-assisted colonoscopy for colorectal cancer surveillance in patients with genetic predisposition - People with Lynch syndrome have a higher hereditary risk of colon cancer.

28 Dec 2022

Colorectal cancer doesn’t wait - DNA methylation tests facilitate earlier treatment

In this interview, Yantao Li and Zhe Wang, Director of Cancer Early Screening Products and the Product Director of Oncology at BGI Genomics, talks to NewsMedical about colorectal cancer (CRC), including why incidences are important and the importance of screening.

From BGI Genomics 6 Dec 2022

Researchers receive NIH grant to develop mRNA vaccines to deter cancer development

A multidisciplinary team of Weill Cornell Medicine researchers have received a five-year $5.7 million grant from the National Cancer Institute at the National Institutes of Health to fund a center aimed at developing messenger RNA (mRNA) vaccines to deter cancer development in at-risk groups.

11 Nov 2022

Hereditary genes correlate with a greater probability of developing cancer mutations, finds study

A study of 11,000 cancer patients reveals 42 hereditary genes which predispose individuals to a higher number of mutations that correlate with a greater probability of developing cancer.

5 Jul 2022

Aspirin changes the way colorectal cancer cells evolve over time, study reveals

Cancer starts when cells start dividing uncontrollably. Scientists have known that taking aspirin can help protect against the development of colorectal cancer – cancer afflicting the colon or rectum – but the exact reason aspirin has this effect has been mostly a mystery.

9 Jun 2022

New fluorescent label provides a clearer picture of how DNA architecture is disrupted in cancer cells

Researchers have developed a new fluorescent label that gives a clearer picture of how DNA architecture is disrupted in cancer cells. The findings could improve cancer diagnoses for patients and classification of future cancer risk.

4 Mar 2022

A Day in the Life of A Clinical Geneticist

In this interview, we spoke to Dr. Julian Barwell, a clinical geneticist, about his day-to-day roles and responsibilities as well as his career highlights.

17 Dec 2021

Urothelial cancers in Lynch Syndrome patients can be detected using a simple, cheap urine test

Researchers have shown for the first time that it is possible to detect signs of urothelial cancer using a simple, postal, urine test in Lynch Syndrome (LS) patients who are at high risk of developing tumors.

11 Nov 2021

Cancer vaccine reduces tumor burden, improves survival in animal model of Lynch syndrome

A new strategy for developing vaccines against cancer showed promise in a proof-of-concept study led by scientists at Weill Cornell Medicine, NewYork-Presbyterian and Heidelberg University Hospital.

2 Aug 2021

New study to test the scalability of offering preventive DNA screening to young adults for cancer risk

A landmark new DNA screening study to identify cancer risk in young adults will go ahead, after Monash University researcher Associate Professor Paul Lacaze was awarded a $2.97 million Medical Research Future Fund (MRFF) grant today.

2 Jul 2021

Should colorectal cancer screening start at age 45?

Colorectal cancer rates among young adults are steadily increasing over the years. The United States Task Force has long recommended that people aged 50 to 75 get screened. Now, the U.S. Preventive Services Task Force updated its 2016 recommendation of colorectal screening for people aged 50, down to 45 years old. The five-year earlier screening can save many lives by allowing earlier diagnosis and treatment of the condition.

21 May 2021