Malignant News and Research

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One-Pot-LAMP: A promising tool for non-small cell lung cancer diagnosis

Researchers assessed the efficiency of a genetic decoding system for diagnosing non-small cell lung cancer (NSCLC).

16 Mar 2023

AI model empowers atopic dermatitis patients to detect complications from bacterial or viral infections

A team of dermatologists has developed an artificial intelligence (AI) model that empowers atopic dermatitis (AD) patients to detect complications from bacterial or viral infections and distinguish between eczema and skin lesions caused by a type of blood cancer.

14 Mar 2023

Scientists identify the cause of leukemia in people with trisomy 21

People with a third copy of chromosome 21, known as trisomy 21, are at high risk of developing Acute Myeloid Leukaemia (AML), an aggressive form of blood cancer.

10 Mar 2023

Study reveals molecular basis of how CAMSAP3 protein stabilizes microtubules within cells

Like poles support a tent, microtubules-;hollow cylindrical structures made of tubulin protein-;support eukaryotic cells.

9 Mar 2023

Detection and targeting of splicing deregulation reveal a potential strategy for pAML therapy

Pediatric acute myeloid leukemia or pAML is a childhood blood cancer, one that has proved confounding to clinicians and researchers, with a high relapse rate and relatively few identified genetic mutations (compared to the adult version) that might explain its cause.

8 Mar 2023

Study unveils a key factor involved in the DNA damage response and repair

A research team, affiliated with UNIST has unveiled a key factor involved in the DNA damage response (DDR), homologous recombination (HR) and DNA interstrand crosslink (ICL) repair.

8 Mar 2023

Study finds two substances capable of inhibiting proliferation of glioblastoma cells

Glioblastoma is a malignant tumor of the central nervous system (brain or spinal cord) and one of the deadliest types of cancer.

7 Mar 2023

New research pinpoints key culprit behind brain cancer metastasis in children

New research pinpoints a key cause of metastasis from an aggressive form of brain cancer in children and provides a potential new therapy for treating these tumors in the future.

6 Mar 2023

People with atopy have lower prevalence of cancers in extracutaneous sites and reduced melanoma risk

Fewer cases of melanoma were observed in people with a history of atopic diseases, such as allergic asthma or rhinitis, than in nonatopic people.

6 Mar 2023

Discovery about cell membrane 'blebs' could lead to new ways to fight melanoma

Cell membrane protrusions called blebs that typically signify the end of life for healthy cells do the opposite for melanoma cells, activating processes in these cells that help them to survive and spread, a UT Southwestern study suggests.

3 Mar 2023

New way to carry drugs across the blood-brain barrier using nanoparticles

Brain tumors are notoriously hard to treat. One reason is the challenge posed by the blood-brain barrier, a network of blood vessels and tissue with closely spaced cells.

3 Mar 2023

Study identifies a potential new targeted drug for treating acute myeloid leukemia

Targeted drugs have been developed to supplement chemotherapy in the treatment of cancer. These drugs only affect cancer cells, leaving healthy cells alone.

23 Feb 2023

Disruptive symptoms and potential complications of enlarged prostate

Half of all men develop enlarged prostates -; also called benign prostatic hyperplasia -; by the time they're 50 years old. The walnut-sized gland never stops slowly growing.

22 Feb 2023

Small molecule inhibitor reverses malignant hyper-editing by an inflammation-induced protein isoform

Researchers at University of California San Diego School of Medicine, Sanford Stem Cell Institute and Moores Cancer Center report that a late-stage, pre-clinical small molecule inhibitor, called rebecsinib, reverses malignant hyper-editing by an inflammation-induced protein isoform, known as ADAR1 p150.

16 Feb 2023

Study highlights the interconnectedness of autoimmunity and cancer

In a recent study published in the journal Immunity, researchers reviewed the T cell response in cancer and autoimmunity to propose strategies for more effective immunotherapies.

15 Feb 2023

What is the tolerability profile and rate of recurrent CDI after administrating microbiome therapeutic SER-109 post-antibiotic treatment?

Researchers investigated the tolerability and safety of a microbiome therapy called SER-109 to treat recurrent infections of Clostridioides difficile in adults.

15 Feb 2023

New method for detecting cancers could help provide clearer disease prognoses

Thanks to a new prognostic method for detecting cancers including cancer of the large intestine, doctors could provide clearer disease prognoses and predict which patients will respond best to immunotherapy.

9 Feb 2023

New strategies to beat rare tumors of the adrenal gland

Only one in 100,000 people suffer from a pheochromocytoma, a tumor of the adrenal gland. If the tumor has already metastasized, a radioactive compound can be used to detect malignant cells that have spread to other parts of the body, and to irradiate them from the inside.

9 Feb 2023

Can commercial AI-based CAD software improve the detection rate of actionable lung nodules on chest radiographs?

Researchers performed a single-center, open-label RCT to investigate whether commercial AI-debased CAD system could improve the detection rate of actionable lung nodules on chest radiographs.

9 Feb 2023

Immunosuppressive drug methotrexate linked to increased risk of three types of skin cancer

The immunosuppressive drug methotrexate (MTX) can be linked to an elevated risk of three types of skin cancer, a new study by University of Gothenburg researchers shows.

7 Feb 2023

Malignant News and Research

One-Pot-LAMP: A promising tool for non-small cell lung cancer diagnosis

AI model empowers atopic dermatitis patients to detect complications from bacterial or viral infections

Scientists identify the cause of leukemia in people with trisomy 21

Study reveals molecular basis of how CAMSAP3 protein stabilizes microtubules within cells

Detection and targeting of splicing deregulation reveal a potential strategy for pAML therapy

Study unveils a key factor involved in the DNA damage response and repair

Study finds two substances capable of inhibiting proliferation of glioblastoma cells

New research pinpoints key culprit behind brain cancer metastasis in children

People with atopy have lower prevalence of cancers in extracutaneous sites and reduced melanoma risk

Discovery about cell membrane 'blebs' could lead to new ways to fight melanoma

New way to carry drugs across the blood-brain barrier using nanoparticles

Study identifies a potential new targeted drug for treating acute myeloid leukemia

Disruptive symptoms and potential complications of enlarged prostate

Small molecule inhibitor reverses malignant hyper-editing by an inflammation-induced protein isoform

Study highlights the interconnectedness of autoimmunity and cancer

What is the tolerability profile and rate of recurrent CDI after administrating microbiome therapeutic SER-109 post-antibiotic treatment?

New method for detecting cancers could help provide clearer disease prognoses

New strategies to beat rare tumors of the adrenal gland

Can commercial AI-based CAD software improve the detection rate of actionable lung nodules on chest radiographs?

Immunosuppressive drug methotrexate linked to increased risk of three types of skin cancer

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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