Malignant News and Research

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Radiologists use special MRI to identify brain cancer early

A special type of magnetic resonance imaging (MRI) can depict changes in blood volume in the brain that often precede cancerous transformation of brain tumors, according to a new study published in the April issue of the journal Radiology.

26 Mar 2008

MRI's high false positive rate has little impact on women's choice of preventive mastectomy

Magnetic resonance imaging (MRI) falsely detects breast cancer in five out of every six positive scans according to new research into the use of MRI for women with a high, inherited risk of developing the disease.

26 Mar 2008

Red wine antioxidant resveratrol kills cancer

Rochester researchers showed for the first time that a natural antioxidant found in grape skins and red wine can help destroy pancreatic cancer cells by reaching to the cell's core energy source, or mitochondria, and crippling its function.

26 Mar 2008

HRT increases breast cancer recurrence

Hormone replacement therapy (HRT) for peri- and postmenopausal symptoms increases disease recurrence in breast cancer survivors, according to an article published online March 25 in the Journal of the National Cancer Institute .

26 Mar 2008

Groundbreaking surgery removes all abdominal organs to get at cancer

In groundbreaking surgery a patient has had all of the organs in the abdomen temporarily removed so surgeons could operate on a cancerous tumour.

25 Mar 2008

New hope for children with bilateral Wilms tumors

Physicians at St. Jude Children's Research Hospital have demonstrated that children with bilateral Wilms tumor, a cancer of the kidneys, can retain normal function in both kidneys by undergoing a procedure called bilateral nephron-sparing surgery, even when preoperative scans suggest that the tumors are inoperable.

25 Mar 2008

Cell therapies for diabetes, cancer

Therapies using stem cell transplants are advancing promising treatments for such conditions as Alzheimer's Disease, neurological diseases and spinal cord injury, and heart disease.

20 Mar 2008

Scans spot hidden tumors in Li-Fraumeni syndrome

Researchers at Dana-Farber Cancer Institute report that full-body PET/CT scanning detected unsuspected, treatable tumors in 3 of 15 patients with Li-Fraumeni syndrome (LFS), a rare genetic cancer syndrome for which no screening tests have been recommended.

19 Mar 2008

Potential new neuronal tumor suppressor

In a G&D paper published online ahead of its April 1 print publication date, Dr. William Kaelin (Dana Farber Cancer Institute) and colleagues identify a potential new neuronal tumor suppressor.

18 Mar 2008

Researchers discover signaling system that halts the growth of a childhood brain cancer

A discovery by St. Jude Children's Research Hospital scientists suggests a safer way to treat medulloblastoma, a rare but often fatal childhood brain tumor.

17 Mar 2008

Researchers study new drug and indications for heated chemotherapy treatment

Studies have shown that surgery combined with Intraperitoneal Hyperthermic Chemotherapy (IPHC) can improve survival rates for select patients with peritoneal carcinoma (cancer of the lining of the abdominal cavity) that has spread from colorectal or appendix cancer.

17 Mar 2008

Routinely used diagnostic approaches: only limited diagnostic sensitivity for bile duct cancer?

Surgery is the only curative treatment in patients with bile duct cancer.

14 Mar 2008

Psychological intervention reduces postembolization pain

Psychological intervention has been shown to reduce the postembolization pain during hepatic arterial chemoembolizatiom therapy.

14 Mar 2008

Study shows Parkinson's disease drug dopamine might work in cancer patients

A study published in the March 13 online issue of The Journal of Clinical Investigation shows that dopamine, a drug currently used to treat Parkinson's disease and other illnesses, also might work in cancer patients.

14 Mar 2008

Is deep-vein thrombosis lurking in your legs?

They kill 300,000 people a year - but most of them could be prevented. They strike more than a million people every year, most of them out of the blue - and half without causing symptoms.

14 Mar 2008

Nuclear protein SATB1 triggers aggressive breast cancer

SATB1 is a nuclear protein well known for its crucial role in regulating gene expression during the differentiation and activation of T cells, making it a key player in the immune system.

13 Mar 2008

Switch for programmed cell death promotes spread of glioblastoma

Malignant tumors have usually lost their ability to destroy themselves by programmed cell death, or apoptosis.

12 Mar 2008

COX-2 expression is marker for cancer development in some benign breast biopsies

It's a good news, bad news situation. Some women who have a breast biopsy are told that while they don't have cancer, they do have atypical hyperplasia -- cells that aren't quite normal and might become cancerous someday.

12 Mar 2008

Discovery of new protein family that may play an important role in preventing inflammatory diseases

A University of Central Florida research team has discovered a new protein family that may play an important role in preventing inflammatory diseases such as arthritis, some forms of cancer and even heart disease.

11 Mar 2008

Mouse model for human malignant mesothelioma

Scientists have established a mouse model for human malignant mesothelioma (MM) that will provide valuable insight into cancer development and progression along with new directions for design of therapeutic strategies.

11 Mar 2008