Malignant News and Research

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Adenovirus used to destroy cancer cells

With nearly $1 million in government funding, University of Rochester scientists are testing a new innovation in biotherapy by altering a common childhood respiratory virus, the adenovirus, to destroy cancer cells.

23 Jun 2007

Novel therapeutic cancer strategy

Cancer sometimes involves processes that should only occur in the embryo being mistakenly reactivated in adult cells.

20 Jun 2007

Affluent society faces greater risks for skin cancer

Skin cancer levels have shown a significant increase in Northern Ireland since the early 1990s and are more likely to affect men, older people and those living in more affluent areas, according to a study just published in the June issue of British Journal of Dermatology.

15 Jun 2007

Nanoparticle-enabled peptide delivery triggers tumor regression

Cells possess a variety of ways of dealing with mutations that can cause them to grow uncontrollably and eventually form a tumor. The tumor suppressor gene p53 plays a critical role in these cancer prevention processes, largely by triggering a form a cell death known as apoptosis.

14 Jun 2007

Malaria and Epstein-Barr virus in Africa

Endemic Burkitt lymphoma is a form of cancer that accounts for up to 74% of malignant disorders in children in equatorial Africa.

14 Jun 2007

A single cancer stem cell is sufficient to initiate and maintain a malignant tumor

At the heart of most, if not all cancers, lie a handful of wayward stem cells that feed the ever growing tumor mass, but their scarcity make it difficult for scientists to study them. Now, times of plenty may lie ahead as a breast cancer cell line , established long ago , turned out to behave a lot like cancer stem cells.

14 Jun 2007

New Rochester program to coordinate patient care, research for patients suffering with brain and spinal tumors

The University of Rochester Medical Center and its Department of Neurosurgery are establishing a new multidisciplinary program to coordinate patient care, research and community outreach efforts for patients suffering with brain and spinal tumors.

8 Jun 2007

Talcum powder stunts cancer growth

Talcum powder has been used for generations to soothe babies diaper rash and freshen women's faces.

8 Jun 2007

Examination of cancer-related fatigue

In a special publication sent to thousands of oncologists nationwide this month, University of Rochester Medical Center scientists offer an in-depth examination of cancer-related fatigue, with hope that a better understanding of the topic will prompt new research and treatment.

8 Jun 2007

Cochlear implant restores hearing to patient with von Hippel-Lindau disease

Researchers at Georgetown University Medical Center and the National Institutes of Health (NIH) have, for the first time, used a bionic ear to restore hearing in a patient with von Hippel-Lindau disease.

8 Jun 2007

VEGF Trap (aflibercept) shows activity in patients with advanced ovarian cancer

Preliminary results of a randomized, international Phase II trial of VEGF Trap (aflibercept) show activity in patients with recurrent epithelial ovarian cancer (EOC) who had received three or four prior chemotherapy regimens and had become resistant to platinum-based chemotherapy agents.

5 Jun 2007

Study finds lymphoma drug effective over long term

Eight years after being treated with a new drug for non-Hodgkin's lymphoma, 86 percent of patients were still alive and half had not had a relapse of their disease, according to researchers from the University of Michigan Comprehensive Cancer Center.

5 Jun 2007

Revlimid may change the way physicians treat multiple myeloma

Findings from a Phase III study by the Eastern Cooperative Oncology Group (ECOG 4A03) were presented yesterday at the American Society of Clinical Oncology (ASCO) meeting in Chicago and demonstrate the benefits of using Revlimid (lenalidomide) with reduced doses of the steroid dexamethasone.

5 Jun 2007

PET accurately identifies esophageal cancer patients' positive responses to chemotherapy

Early metabolic imaging with positron emission tomography (PET) accurately identifies patients responding to chemotherapy for esophageal cancer, noted German researchers at the 54th Annual Meeting of SNM, the world's largest society for molecular imaging and nuclear medicine professionals.

5 Jun 2007

Predicting treatment responses earlier for brain tumor patients

Using metabolic or molecular imaging to measure brain tumor patients' response to treatment is a powerful predictor of survival, notes a first-of-its-kind study presented at the 54th Annual Meeting of SNM, the world's largest society for molecular imaging and nuclear medicine professionals.

5 Jun 2007

Percutaneous ethanol injection helps manage bone metastasis in thyroid cancer patients

Percutaneous ethanol injection (PEI), an injection of ethanol (alcohol) through the skin directly into a bone tumor to kill cancer cells, may be a valuable ancillary treatment for thyroid cancer patients whose cancer has spread to the bone.

5 Jun 2007

Diagnosing skin cancers with laser-based system

In an early step toward nonsurgical screening for malignant skin cancers, Duke University chemists have demonstrated a laser-based system that can capture three-dimensional images of the chemical and structural changes under way beneath the surface of human skin.

5 Jun 2007