Mass Spectrometry News and Research

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Mass spectrometry is an analytical method used to identify different compounds based on the atomic sample constitution of the molecules and their charge state, which enables “blind” analysis of an unknown sample without any prior knowledge of its composition.

Scientists identify altered proteins that predict islet autoimmunity

Scientists have taken an important step forward in predicting who will develop Type 1 diabetes months before symptoms appear.

29 Jun 2023

$New facile strategy for proteome analysis using ultracentrifugation fractionation$

New facile strategy for proteome analysis using ultracentrifugation fractionation

Urine is one of the attractive sources for early and sensitive biomarker discovery since it can accumulate and reflect changes in the human body while being collected non-invasively.

16 Jun 2023

Experts identify a novel fucosylated heparan sulfate from the midgut gland of the Japanese scallop

Glycosaminoglycans (GAGs), including chondroitin sulfate (CS), heparan sulfate (HS), heparin, and hyaluronan are linear and acidic polysaccharides found in the extracellular matrix of all animal tissues. GAGs are widely used as functional ingredients in health products, pharmaceuticals, and cosmetics, and are prepared from biological samples such as shark cartilage and porcine intestinal mucosa. Consequently, the demand for new sources of GAGs is ever-present. For example, the supply source of the anticoagulant heparin-;generally prepared from porcine intestinal mucosa in China-;was threatened by African swine fever in 2018.

15 Jun 2023

Researchers create a diagnostic test to identify functional sperm in infertile men

In a recent study, researchers created a diagnostic test to identify functional sperm in infertile men that could change the treatment of male infertility and assisted reproductive technology.

14 Jun 2023

Do COVID-19 drugs in aquatic matrices negatively impact microalgae and cyanobacteria communities?

Researchers evaluated the presence of coronavirus disease 2019 (COVID-19) drugs in river water.

8 Jun 2023

Study shows Alzheimer’s disease-associated retinopathy can be ameliorated by dietary lysophosphatidylcholine-EPA/DHA

Researchers evaluated the impact of dietary lysophosphatidylcholine (LPC), comprising eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), on retinal function in Alzheimer’s disease (AD)-associated retinopathy.

8 Jun 2023

Scientists uncover key molecular culprit in ALS: PEG10 gene implicated in pathogenesis

UBQLN2 dysfunction in ALS leads to elevated PEG10 levels, suggesting a role for retrotransposon activity in the disease. PEG10's nuclear localization alters gene expression involved in axon remodeling, implicating it as a contributing mechanism in ALS.

7 Jun 2023

Breakthrough: Sequencing functional antibody proteins directly from human blood

Rapid Novor Inc., the world’s leader in mass spectrometry (MS)-based antibody protein sequencing, announced today that its REpAb® antibody discovery platform was used to successfully sequence a complex mixture of functional antibodies directly from the serum of a human patient after receiving a COVID-19 vaccine.

6 Jun 2023

Shaping the human metabolome: the impact of a ketogenic diet

Researchers explored how the human metabolic fingerprint changes with a ketogenic diet (KD).

6 Jun 2023

How lipid metabolites in the gut aid in regulatory T-cell differentiation

Researchers describe the Treg-cell-inducing activity of lipid extracts from the feces of specific-pathogen-free mice.

6 Jun 2023

When Spectrometry bridges the gap between Proteomics and Biology

In this new episode of omg OMx, Kate Sumpo talks to Balyn Zaro about her research, experiences, and insights as a biologist in proteomics and spectrometry.

From Bruker Life Sciences Mass Spectrometry 2 Jun 2023

Novel technology helps analyze tumor growth in another dimension

Tumors are composed of rapidly multiplying cancer cells. Understanding which biochemical processes fuel their relentless growth can provide hints at therapeutic targets.

2 Jun 2023

Juicy findings: Chinese consumers embrace fruit peel delights, scientists examine nutritional value and pesticide concerns

Research explores the consumption of fruit peels by Chinese consumers, highlighting their nutritional value and pesticide residues. It provides insights into methods of pesticide detection and removal, as well as the physiological benefits of fruit peels, aiming to guide informed consumption and contribute to further research in this area.

1 Jun 2023

Study measures the annual prevalence of nontuberculous mycobacterial lung disease in Ontario, Canada

Researchers determined the prevalence of nontuberculous mycobacterial pulmonary disease (NTM-PD) in 2020.

1 Jun 2023

Real-world management and outcomes of U.S. patients treated with BpaL for rifampin-resistant tuberculosis

Researchers reported on the treatment of rifampin-resistant tuberculosis in the United States using the FDA approved bedaquiline, pretomanid, and linezolid (BPaL) therapy.

1 Jun 2023

Can adherence to the Mediterranean diet reduce gestational stress and anxiety in pregnant women?

Researchers investigated the influence of structured Mediterranean diet intervention on the anxiety and stress levels.

1 Jun 2023

Dutch scientists unveil the integral role of CD5L protein in IgM structure and function

Researchers in the Netherlands assessed the structure of human circulatory IgM and its relationship with the small CD5L protein.

31 May 2023

Modest reduction in beta-amyloidogenic processing of APP may be a viable strategy to prevent Alzheimer's disease

A new study conducted by researchers at the University of Eastern Finland discovered that the APP A673T genetic variant, which protects against Alzheimer’s disease, alters levels of several proteins and peptides linked to amyloid-beta metabolism in human biofluids and cell culture models, including amyloid beta itself.

26 May 2023

Top-Down Proteomics: Bridging the Genotype-to-Phenotype Gap

In this interview conducted at Pittcon 2023 in Philadelphia, Pennsylvania, we spoke to this year's recipient of the Pittsburgh Analytical Chemistry Award, Neil Kelleher, about his work in top-down proteinomics.

From Pittcon 26 May 2023

Scientists unveil a metabolic Achilles' heel in pancreatic cancer

Research unveils the significance of uridine as a metabolic fuel in pancreatic ductal adenocarcinoma (PDA) cells under glucose-deprived conditions. Uridine utilization, mediated by uridine phosphorylase 1 (UPP1), supports redox balance, survival, and proliferation in PDA, highlighting its potential as a novel therapeutic target in the treatment of this resistant cancer.

23 May 2023

Mass Spectrometry News and Research

Further Reading

Scientists identify altered proteins that predict islet autoimmunity

New facile strategy for proteome analysis using ultracentrifugation fractionation

Experts identify a novel fucosylated heparan sulfate from the midgut gland of the Japanese scallop

Researchers create a diagnostic test to identify functional sperm in infertile men

Do COVID-19 drugs in aquatic matrices negatively impact microalgae and cyanobacteria communities?

Study shows Alzheimer’s disease-associated retinopathy can be ameliorated by dietary lysophosphatidylcholine-EPA/DHA

Scientists uncover key molecular culprit in ALS: PEG10 gene implicated in pathogenesis

Breakthrough: Sequencing functional antibody proteins directly from human blood

Shaping the human metabolome: the impact of a ketogenic diet

How lipid metabolites in the gut aid in regulatory T-cell differentiation

When Spectrometry bridges the gap between Proteomics and Biology

Novel technology helps analyze tumor growth in another dimension

Juicy findings: Chinese consumers embrace fruit peel delights, scientists examine nutritional value and pesticide concerns

Study measures the annual prevalence of nontuberculous mycobacterial lung disease in Ontario, Canada

Real-world management and outcomes of U.S. patients treated with BpaL for rifampin-resistant tuberculosis

Can adherence to the Mediterranean diet reduce gestational stress and anxiety in pregnant women?

Dutch scientists unveil the integral role of CD5L protein in IgM structure and function

Modest reduction in beta-amyloidogenic processing of APP may be a viable strategy to prevent Alzheimer's disease

Top-Down Proteomics: Bridging the Genotype-to-Phenotype Gap

Scientists unveil a metabolic Achilles' heel in pancreatic cancer

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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