Mass Spectrometry News and Research

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Mass spectrometry is an analytical method used to identify different compounds based on the atomic sample constitution of the molecules and their charge state, which enables “blind” analysis of an unknown sample without any prior knowledge of its composition.

Gingival crevicular fluid predicts periodontal attachment loss

Analysis of gingival crevicular fluid using mass spectrometry could be used to predict sites of periodontal attachment loss in individuals undergoing maintenance therapy for periodontitis, report researchers.

18 Oct 2012

VeriStrat identifies NSCLC patients likely to respond to erlotinib

A study, published in the November 2012 issue of the International Association for the Study of Lung Cancer's (IASLC) Journal of Thoracic Oncology, showed the plasma test VeriStrat can predict response but not survival benefit from erlotinib. The study was conducted on a subset of patients enrolled in the NCIC Clinical Trials Group, BR.21 phase III trial of erlotinib versus placebo in previously treated advanced non-small cell lung cancer patients.

16 Oct 2012

New mass spectrometry helps identify bacteria in clinical specimens within minutes

New mass spectrometry technology is helping Le Bonheur Children's physicians analyze microbiology samples quickly - identifying specific bacteria present in a sample within minutes.

11 Oct 2012

ProteoWizard Toolkit interprets multi-platform mass spectrometry data

The world's leading mass spectrometer manufacturers have agreed to license technology that enabled University of Southern California (USC) researchers to develop software that, for the first time, allows scientists to easily use and share research data collected across proprietary platforms.

From Thermo Fisher Scientific Inc. 10 Oct 2012

Bruker introduces Toxtyper clinical mass spectrometry solution

At the annual conference of the DGKL, Bruker today announced the European launch of the novel, automated Toxtyper clinical mass spectrometry solution to meet the increasing demands for LC-MS/MS throughput and data quality in routine toxicology laboratories without the need for mass spectrometry expertise.

26 Sep 2012

New technique can identify cell-secreted proteins

Researchers from North Carolina State University have developed a new technique to identify the proteins secreted by a cell. The new approach should help researchers collect precise data on cell biology, which is critical in fields ranging from zoology to cancer research.

26 Sep 2012

Lack of cytokeratin 6A may lead to eye infections

Exposed tissue surfaces, including skin and mucous membranes, are under constant threat of attack by microorganisms in the environment. The layer of cells that line these areas, known as epithelial cells, are the first line of defense against these pathogens, but the underlying molecular mechanisms that allow them to repel microbes are unknown.

25 Sep 2012

Small fragments of keratin protein in the eye play a key role in warding off pathogens

When it comes to germ-busting power, the eyes have it, according to a discovery by University of California, Berkeley, researchers that could lead to new, inexpensive antimicrobial drugs.

25 Sep 2012

RTI International receives NIH contract to serve as regional metabolomics research core center

RTI International has been awarded a five-year contract from the National Institutes of Health to serve as a regional comprehensive metabolomics research core center.

24 Sep 2012

Researchers obtain first detailed and complete picture of PRC2 protein

The first detailed and complete picture of a protein complex that is tied to human birth defects as well as the progression of many forms of cancer has been obtained by an international team of researchers led by scientists with the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab).

18 Sep 2012

Modifying fat intake during pregnancy benefits children regardless of mother's size

If you are overweight and pregnant, your baby isn't destined to a life of obesity after all, according to a new research report published online in The FASEB Journal. In the report, a team of U.S. scientists show that modifying fat intake during pregnancy to a moderate level is enough to benefit the child regardless of the mother's size.

17 Sep 2012

Breath testing could discriminate between benign and malignant pulmonary nodules

A pilot study, published in the October 2012 issue of the International Association for the Study of Lung Cancer's (IASLC) Journal of Thoracic Oncology, showed that breath testing could be used to discriminate between benign and malignant pulmonary nodules.

17 Sep 2012

Bruker introduces new solariX XR Fourier Transform Mass Spectrometer with ParaCell

At the 19th International Mass Spectrometry Conference, Bruker today introduced the breakthrough new solariX XR Fourier Transform Mass Spectrometer (FTMS) with the revolutionary ParaCell for extreme mass resolution greater than 10 million.

17 Sep 2012

Changes in Troponin I protein can lead to cardiac muscle malfunction and precipitate heart failure

A new Johns Hopkins study has unraveled the changes in a key cardiac protein that can lead to heart muscle malfunction and precipitate heart failure.

13 Sep 2012

Bruker launches BioPharmaCompass 1.1 software

At the 2012 CASSS 9th Symposium on the Practical Applications of Mass Spectrometry in the Biotechnology Industry, Bruker today launches the first software solution to encompass the complete biopharmaceutical characterization challenge, including glycoforms, impurities and modifications.

From Bruker BioSpin - NMR, EPR and Imaging 12 Sep 2012

AB SCIEX launches Eksigent ekspert nanoLC 400 system

AB SCIEX, a global leader in life science analytical technologies, today announced the launch of the Eksigent ekspert nanoLC 400 system.

10 Sep 2012

DNA synthesis methods: an interview with Clemens Richert

Automated DNA synthesis has been around for almost three decades. The key difference between the established methodology for making oligodeoxynucleotides (short stretches of single-stranded DNA) and our method is the template strand.

7 Sep 2012

UC Davis plans to open West Coast Metabolomics Center

With a $9.3 million startup grant from the National Institutes of Health, the University of California, Davis, has announced plans to open the West Coast Metabolomics Center, a high-tech consortium of research and service laboratories that will help scientists better understand and develop more effective treatments for complex diseases like diabetes, cancer and atherosclerosis.

6 Sep 2012

Molecular ‘timetable’ could aid personalized medicine

Researchers have developed a method, based on analysis of circadian rhythm metabolites in blood samples, which can pinpoint the time of the body’s internal “clock” to within 3 hours.

4 Sep 2012

PRISM technique as accurate as ELISAs in identifying proteins within biological samples

Combining two well-established analytic techniques and adding a twist identifies proteins from blood with as much accuracy and sensitivity as the antibody-based tests used clinically, researchers report this week in Proceedings of the National Academy of Sciences Early Edition online.

4 Sep 2012

Mass Spectrometry News and Research

Further Reading

Gingival crevicular fluid predicts periodontal attachment loss

VeriStrat identifies NSCLC patients likely to respond to erlotinib

New mass spectrometry helps identify bacteria in clinical specimens within minutes

ProteoWizard Toolkit interprets multi-platform mass spectrometry data

Bruker introduces Toxtyper clinical mass spectrometry solution

New technique can identify cell-secreted proteins

Lack of cytokeratin 6A may lead to eye infections

Small fragments of keratin protein in the eye play a key role in warding off pathogens

RTI International receives NIH contract to serve as regional metabolomics research core center

Researchers obtain first detailed and complete picture of PRC2 protein

Modifying fat intake during pregnancy benefits children regardless of mother's size

Breath testing could discriminate between benign and malignant pulmonary nodules

Bruker introduces new solariX XR Fourier Transform Mass Spectrometer with ParaCell

Changes in Troponin I protein can lead to cardiac muscle malfunction and precipitate heart failure

Bruker launches BioPharmaCompass 1.1 software

AB SCIEX launches Eksigent ekspert nanoLC 400 system

DNA synthesis methods: an interview with Clemens Richert

UC Davis plans to open West Coast Metabolomics Center

Molecular ‘timetable’ could aid personalized medicine

PRISM technique as accurate as ELISAs in identifying proteins within biological samples

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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