Mechanobiology News and Research

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Researchers develop powerful new approach to improve maturation of miniature kidneys

In recent years, researchers have created mini-organs known as organoids in the culture dish that contain many of the cell types and complex microarchitectures found in human organs, such as the kidney, liver, intestine, and even the brain.

13 Feb 2019

Key insights into the application, production of bioactive materials

Anatomy, Modeling and Biomaterial Fabrication for Dental and Maxillofacial Applications provides readers with information about dental implants and biomaterial fabrication for maxillofacial procedures and dental bone / tissue repair.

19 Oct 2018

Mechanical engineer receives NIH grant to study various aspects of cell group behavior

Researchers have thought that cancer begins when a single cell goes rogue in the body, then begins to grow and multiply.

3 Aug 2018

UH scientist receives grant to examine understudied part of glaucoma

UH College of Optometry biomedical engineer Vijaykrishna Raghunathan has received $765,000 from the National Institutes of Health to examine an understudied part of glaucoma - the ebb and flow of aqueous humor, the liquid in the eye whose regulation controls eye pressure.

20 Jun 2018

Penn State professor receives NSF CAREER award to study mechanobiology of cell differentiation

Esther Gomez, assistant professor of chemical engineering and biomedical engineering, Penn State, has received the National Science Foundation's prestigious Early Career award to better understand the mechanobiology of mesenchymal-epithelial transition.

4 May 2018

New noninvasive technique uses blood test to detect brain tumor biomarkers

Taking a biopsy of a brain tumor is a complicated and invasive surgical process, but a team of researchers at Washington University in St. Louis is developing a way that allows them to detect tumor biomarkers through a simple blood test.

26 Apr 2018

Study on infant bone strength could aid in design of safer car seats

Researchers at the University of Sheffield have successfully used computer simulated models and medical imaging to test the strength of young children's bones, producing results which could help car seat manufacturers design safer car seats for young children.

16 Mar 2018

New study provides better understanding of asymmetric cell division

Stem cells are the basic material from which mature, specialised cells such as muscle and blood cells are produced -- this process is known as differentiation.

28 Feb 2018

New biomaterials-based system improves T-cell production

T cells play a key role in the body's immune response against pathogens. As a new class of therapeutic approaches, T cells are being harnessed to fight cancer, promising more precise, longer-lasting mitigation than traditional, chemical-based approaches.

18 Jan 2018

Scientists develop unique technique to map elasticity of cell components

Scientists at Université de Montréal have developed a unique technique to map, on a scale of milliseconds, the elasticity of the components inside a cell.

17 Jan 2018

Biomedical, Biophysical and Biological Applications of AFM

An interview with Dr. Thomas Mueller, Director of Product Management at Bruker Nano Surfaces conducted by April Cashin-Garbutt, MA (Cantab).

From Bruker Nano Surfaces and Metrology 10 Jan 2018

Using AFM to characterize cancer cells

An interview with Dr. Jim Gimzewski, UCLA conducted by April Cashin-Garbutt, MA (Cantab).

From Bruker Nano Surfaces and Metrology 28 Nov 2017

Study identifies molecular pathway critical to development of fibrosis

A study led by investigators at Massachusetts General Hospital and University Health Network in Toronto has identified a molecular pathway that appears to be critical to the development of fibrosis - scarring and excessive tissue deposition that result from abnormal healing responses and can compromise the function of vital organs.

15 Nov 2017

Mechanical memory of cells could hold new clues to tumor invasion

In the body, cells move around to form organs during development; to heal wounds; and when they metastasize from cancerous tumors.

28 Oct 2017

WPI professor developing new tools to better detect concussions in real time

As fall sports seasons get under way and concerns related to concussions in contact sports continue to grow, a Worcester Polytechnic Institute biomedical engineering professor is developing better tools to understand the mechanics of traumatic brain injuries in athletes.

13 Sep 2017

Gelesis reports completion of treatment for last patient in pivotal GLOW study

Gelesis, Inc., a biotechnology company developing a novel category of therapies to safely induce weight loss, improve glycemic control, and treat other chronic diseases related to the gastrointestinal (GI) pathway, is pleased to report today that the last patient has completed treatment in the pivotal GLOW (Gelesis Loss Of Weight) Study.

12 Jul 2017

Singapore researchers discover new mechanism in the liver's response to blocked bile ducts

A multi-disciplinary team of researchers from the Mechanobiology Institute, Singapore at the National University of Singapore, the Institute of Bioengineering and Nanotechnology of A*STAR, and BioSyM, Singapore-MIT Alliance for Research and Technology have described the mechanical principles adopted by liver cells as they remove excess bile during obstructive cholestasis.

30 Jun 2017

Penn scientists develop computer model that better simulates how cells spread in fibrous environments

One area of research within mechanobiology, the study of how physical forces influence biological processes, is on the interplay between cells and their environment and how it impacts their ability to grow and spread.

16 Jun 2017

Researchers develop nerve wrapping nanofiber mesh to facilitate regeneration, restore function

A NIMS-Osaka University joint research team developed a mesh which can be wrapped around injured peripheral nerves to facilitate their regeneration and restore their functions.

28 Feb 2017

Drugs that target tissue stiffness could potentially prevent cancer metastasis

In order for cancer to spread, malignant cells must break away from a tumor and through the tough netting of extracellular matrix, or ECM, that surrounds it. To fit through the holes in this net, those cancerous cells must elongate into a torpedo-like shape.

22 Feb 2017