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Bariatric surgery may mitigate the natural history of cognitive decline in people with obesity

Within the next 10 years, it's projected that up to 50% of United States adults will be affected by obesity, which is associated with cognitive impairment and dementia.

8 Jan 2024

Novel population health tool for predicting ICU survivorship and mortality in older adults

A significant obstacle to improving care and outcomes for intensive care unit (ICU) patients is the unexpected nature of becoming seriously ill.

4 Jan 2024

Researchers develop peptide to target "chaotic" MYC protein in 75% of cancers

Meet MYC, the shapeless protein responsible for making the majority of human cancer cases worse.

4 Jan 2024

Exploring environmental influences on pregnancy, child health and disabilities

How does a pregnant person's environment, diet, stress, medications and social wellbeing affect their pregnancy and -; down the road -; their child's health?

3 Jan 2024

New study demystifies clinicians' decision-making process for drug-drug interactions

Drug-drug interactions causing adverse effects are common and can cause significant patient harm and even death.

3 Jan 2024

Existing beta blocker investigated as novel sickle cell therapy

A beta blocker typically used to treat heart problems, hemangioma, migraines and anxiety could be a new therapeutic for patients with sickle cell disease. Researchers led by Ankit A. Desai, MD, associate professor of medicine at the Krannert Cardiovascular Research Center (KCVRC) at Indiana University School of Medicine, have been awarded a $3 million grant by the U.S. Department of Defense to evaluate the efficacy of this drug.

3 Jan 2024

Novel exercise approach offers significant benefits for children with cerebral palsy

Children with cerebral palsy (CP) have reported significant gains in cardiovascular fitness and mobility after taking part in a landmark research project led by The University of Queensland.

3 Jan 2024

Healthy fats from fish and nuts may slow lung scarring, delay transplants

Could healthy fats found in nuts and fish slow the progression of potentially deadly lung scarring known as pulmonary fibrosis and delay the need for lung transplants?

2 Jan 2024

Large-scale study uncovers modifiable risk factors for young-onset dementia

Researchers have identified a wide range of risk factors for young-onset dementia.

26 Dec 2023

New model links RNA editing glitch to early-stage type 1 diabetes

Hebrew University study proposes a new model suggesting that disrupted RNA editing within pancreatic beta cells might initiate an inflammatory response akin to early-stage type 1 diabetes.

26 Dec 2023

Study identifies two stem cell types driving jellyfish tentacle growth

At about the size of a pinkie nail, the jellyfish species Cladonema can regenerate an amputated tentacle in two to three days -; but how? Regenerating functional tissue across species, including salamanders and insects, relies on the ability to form a blastema, a clump of undifferentiated cells that can repair damage and grow into the missing appendage.

25 Dec 2023

Brain injury markers found in the blood months after COVID-19 infection

A new study published today (22 December 2023) in Nature Communications details that markers of brain injury are present in the blood many months after COVID-19 infection, despite inflammation blood tests being normal.

22 Dec 2023

St. Jude researchers crack the code of the β2-adrenergic receptor

Through an international collaboration, scientists at St. Jude Children's Research Hospital leveraged data science, pharmacology and structural information to conduct an atomic-level investigation into how each amino acid in the receptor that binds adrenaline contributes to receptor activity in the presence of this natural ligand.

22 Dec 2023

Shedding new light on the hidden organization of the cytoplasm

Back in 2018, the lab of Christine Mayr, MD, PhD, at Memorial Sloan Kettering Cancer Center (MSK) introduced the world to a key cellular component that had been hiding in plain sight.

21 Dec 2023

Research illustrates how racism is deeply interrelated with poor health outcomes

A team of health equity researchers from several institutions has leveraged a complex web of data to test a hypothesis: That structural racism is associated with resources and structures at the neighborhood level that are closely associated with poor health.

21 Dec 2023

St. Jude researchers reveal structure of Parkinson's-linked proteins

Scientists at St. Jude Children's Research Hospital revealed the complex structure of two Parkinson's disease-related proteins, both of which are implicated in late-onset cases.

21 Dec 2023

Deep flaws in FDA oversight of medical devices, and patient harm, exposed in lawsuits and records

Living with diabetes, Carlton "PeeWee" Gautney Jr. relied on a digital device about the size of a deck of playing cards to pump insulin into his bloodstream.

21 Dec 2023

Shedding light on heat stress during pregnancy with £1.4 million Wellcome Trust grant

Researchers from the Medical Research Council Unit The Gambia (MRCG) at the London School of Hygiene & Tropical Medicine (LSHTM) will continue to evaluate the mechanisms behind the acute and chronic effects of extreme heat on expectant mothers and their unborn children, as part of a £1.4m grant from the Wellcome Trust.

20 Dec 2023

UVA Alzheimer's study pinpoints how tau protein damages brain cells

University of Virginia Alzheimer's researchers have discovered how harmful tau proteins damage the essential operating instructions for our brain cells, a finding which could lead to new treatments.

20 Dec 2023

Widespread cannabis use linked to increase in psychiatric disorders, UMSOM review finds

The widespread use of cannabis (marijuana) and its increased potency are associated with a rise in cannabis-related psychiatric conditions, according to a new University of Maryland School of Medicine (UMSOM) review article that was recently published in the New England Journal of Medicine.

19 Dec 2023

Medical Research News and Research

Bariatric surgery may mitigate the natural history of cognitive decline in people with obesity

Novel population health tool for predicting ICU survivorship and mortality in older adults

Researchers develop peptide to target "chaotic" MYC protein in 75% of cancers

Exploring environmental influences on pregnancy, child health and disabilities

New study demystifies clinicians' decision-making process for drug-drug interactions

Existing beta blocker investigated as novel sickle cell therapy

Novel exercise approach offers significant benefits for children with cerebral palsy

Healthy fats from fish and nuts may slow lung scarring, delay transplants

Large-scale study uncovers modifiable risk factors for young-onset dementia

New model links RNA editing glitch to early-stage type 1 diabetes

Study identifies two stem cell types driving jellyfish tentacle growth

Brain injury markers found in the blood months after COVID-19 infection

St. Jude researchers crack the code of the β2-adrenergic receptor

Shedding new light on the hidden organization of the cytoplasm

Research illustrates how racism is deeply interrelated with poor health outcomes

St. Jude researchers reveal structure of Parkinson's-linked proteins

Deep flaws in FDA oversight of medical devices, and patient harm, exposed in lawsuits and records

Shedding light on heat stress during pregnancy with £1.4 million Wellcome Trust grant

UVA Alzheimer's study pinpoints how tau protein damages brain cells

Widespread cannabis use linked to increase in psychiatric disorders, UMSOM review finds

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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