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Poverty in early childhood linked with higher risk of poor cognitive outcomes

Poverty in early childhood appears to be associated with smaller brain volumes measured through imaging at school age and early adolescence, according to a study published by JAMA Pediatrics, a JAMA Network publication.

29 Oct 2013

Research findings could help define new vaccination applications

New research from the Masonic Cancer Center, University of Minnesota, and the University of Minnesota Center for Immunology has identified key proteins that influence immune response strategies, a finding that could influence new vaccination approaches.

29 Oct 2013

Study reveals that Medicaid beneficiaries with lupus not following treatment plans

Medicaid beneficiaries with lupus are not adequately following their treatment plans, and this puts them at risk for poor health outcomes, according to research presented this week at the American College of Rheumatology Annual Meeting in San Diego. For most lupus medications, fewer than one in three beneficiaries were found to be adherent.

28 Oct 2013

DPP-4 inhibitors may reduce risk of autoimmune diseases

Dipeptidyl peptidase-4 inhibitors commonly used to control blood sugar levels in people with type 2 diabetes may also reduce the risk of autoimmune diseases in these patients, according to research presented this week at the American College of Rheumatology Annual Meeting in San Diego.

28 Oct 2013

Study shows low uptake of HPV vaccination among patients with autoimmune diseases

The number of children and young adults with autoimmune diseases receiving the HPV vaccination is profoundly low despite studies showing the vaccine to be safe and effective, according to research presented this week at the American College of Rheumatology Annual Meeting in San Diego. Given the increased incidence of HPV in people with autoimmune diseases, this research suggests that increased public health efforts are needed.

28 Oct 2013

Rituximab drug may be safe, effective for immunoglobulin G4-related disease treatment

Rituximab (Rituxan) — a drug commonly used rheumatoid arthritis, granulomatosis with polyangiitis (formerly Wegener's), and certain types of cancers — may be a safe and effective treatment for immunoglobulin G4-related disease (commonly called IgG4-RD), according to research presented this week at the American College of Rheumatology Annual Meeting in San Diego.

28 Oct 2013

Two aggressive therapy approaches effective for children with juvenile idiopathic arthritis

Children with juvenile idiopathic arthritis who receive early, aggressive therapy with a combination of medications achieve clinical inactive disease status faster than they would with less aggressive therapy, according to new research presented this week at the American College of Rheumatology Annual Meeting in San Diego.

28 Oct 2013

Study confirms the "seed and soil" theory of metastasis

Oncologists have long puzzled over the fact that after cancer treatment, single cancer cells that are dispersed throughout the body - so-called disseminated tumor cells - are quick to grow and form secondary tumors called metastases in certain organs, while in other organs they metastasize more slowly, sometimes decades later. Such is the case with head and neck squamous cell carcinoma cells, which remain dormant when lodged in bone marrow but rapidly form tumors when they make their way into the lungs.

28 Oct 2013

First Edition: October 25, 2013

Today's headlines include reports and analyses of yesterday's Capitol Hill hearing, which featured website contractors talking about the troubled rollout of healthcare.gov.

25 Oct 2013

NTU launches new CryoEM lab equipped with advanced cryo transmission electron microscope

Nanyang Technological University (NTU) today launched a new electron microscopy lab led by world renowned scientist Professor Daniela Rhodes. Named the NTU Cryo-Electron Microscopy Laboratory, it is also the world's first university research facility to be equipped with an advanced cryo transmission electron microscope fitted with the latest detector/camera ten times more sensitive than a regular electron microscopy camera.

25 Oct 2013

Obsessive-compulsive disorder and Tourette syndrome are highly heritable

An international research consortium led by investigators at Massachusetts General Hospital (MGH) and the University of Chicago has answered several questions about the genetic background of obsessive-compulsive disorder and Tourette syndrome, providing the first direct confirmation that both are highly heritable and also revealing major differences between the underlying genetic makeup of the disorders.

25 Oct 2013

Researchers publish comprehensive review of the benefits, risks of daily aspirin dosage

Researchers at Warwick Medical School have published the most comprehensive review of the benefits and risks of a daily dose of prophylactic aspirin and warn that greater understanding of side effects is needed.

25 Oct 2013

UMMS professor receives EUREKA grant to develop light activated nanoparticles for imaging brain tissue

University of Massachusetts Medical School Assistant Professor of Biochemistry and Molecular Pharmacology Gang Han, PhD, has received a $1.3 million EUREKA (Exceptional Unconventional Research Enabling Knowledge Acceleration) grant from the National Institute of Mental Health to develop light activated nanoparticles that can be used to image live brain tissue.

25 Oct 2013

Whitehead Institute scientists identify novel Parkinson's disease drug target

Using a discovery platform whose components range from yeast cells to human stem cells, Whitehead Institute scientists have identified a novel Parkinson's disease drug target and a compound capable of repairing neurons derived from Parkinson's patients.

25 Oct 2013

Hands-free ultrasound device with clot-busting drug safe for ischemic stroke patients

A study led by researchers at The University of Texas Health Science Center at Houston (UTHealth) showed that a hands-free ultrasound device combined with a clot-busting drug was safe for ischemic stroke patients.

25 Oct 2013

Researchers develop new interactive software game to help children with peanut allergies

Elizabeth McQuaid, Ph.D., a staff psychologist from the Bradley Hasbro Children's Research Center, is leading a research team testing a new interactive software game developed to help children with peanut allergies better manage allergy symptoms, social situations and proper food avoidance.

24 Oct 2013

GW researcher explores successful interventions implemented outside ED to reduce existing ED use

In recent years, many groups, including policy makers and health systems, have looked for ways to reduce the number of visits to the emergency department (ED) as a way to lower costs and improve the quality of care. Research conducted by Jesse Pines, M.D., director of the Office of Clinical Practice Innovation and professor of emergency medicine at the George Washington University (GW) School of Medicine and Health Sciences, explored interventions that had been implemented outside of EDs that were designed to reduce ED use.

24 Oct 2013

Older people with diabetes more likely to develop cognitive deterioration and Alzheimer's disease

Diabetes and dementia are rising dramatically in the United States and worldwide. In the last few years, epidemiological data has accrued showing that older people with diabetes are significantly more likely to develop cognitive deterioration and increased susceptibility to onset of dementia related to Alzheimer's disease.

24 Oct 2013

BUSM researchers capture images of channels that direct proteins to right place in cell membranes

Similar to passengers on an urban transit system, every protein made in the cell has a specific destination and function. Channels in cell membranes help direct these proteins to their appropriate target. Researchers at Boston University School of Medicine and their colleagues have now captured images of these channels as they open to allow proteins to pass through a membrane, while the proteins are being made.

24 Oct 2013

Patient assistance programs help breast cancer patients to learn more about adjuvant therapy

Patient assistance programs can help breast cancer patients meet a variety of needs that can interfere with getting recommended adjuvant therapies such as radiation, chemotherapy, and hormonal treatments, according to a study published recently in the online edition of the Journal of Oncology Practice.

24 Oct 2013

Medical School News and Research

Poverty in early childhood linked with higher risk of poor cognitive outcomes

Research findings could help define new vaccination applications

Study reveals that Medicaid beneficiaries with lupus not following treatment plans

DPP-4 inhibitors may reduce risk of autoimmune diseases

Study shows low uptake of HPV vaccination among patients with autoimmune diseases

Rituximab drug may be safe, effective for immunoglobulin G4-related disease treatment

Two aggressive therapy approaches effective for children with juvenile idiopathic arthritis

Study confirms the "seed and soil" theory of metastasis

First Edition: October 25, 2013

NTU launches new CryoEM lab equipped with advanced cryo transmission electron microscope

Obsessive-compulsive disorder and Tourette syndrome are highly heritable

Researchers publish comprehensive review of the benefits, risks of daily aspirin dosage

UMMS professor receives EUREKA grant to develop light activated nanoparticles for imaging brain tissue

Whitehead Institute scientists identify novel Parkinson's disease drug target

Hands-free ultrasound device with clot-busting drug safe for ischemic stroke patients

Researchers develop new interactive software game to help children with peanut allergies

GW researcher explores successful interventions implemented outside ED to reduce existing ED use

Older people with diabetes more likely to develop cognitive deterioration and Alzheimer's disease

BUSM researchers capture images of channels that direct proteins to right place in cell membranes

Patient assistance programs help breast cancer patients to learn more about adjuvant therapy

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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