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Recent data from Silence Therapeutics’ Atu111 pre-clinical study on acute lung injury

Silence Therapeutics plc, a leading RNA interference (RNAi) therapeutics company is pleased to announce that recent data in pre-clinical models demonstrated the efficacy of Atu111 in acute lung injury.

10 Sep 2012

Tight blood sugar control does not benefit pediatric patients undergoing heart surgery

Although some studies have portrayed tight blood sugar control as a potential means of lowering infection rates in critically ill adults, a new study-led by principal investigator Michael Agus, MD, director of the Medicine Critical Care Program at Boston Children's Hospital-found no indication that the approach benefits pediatric patients undergoing heart surgery.

10 Sep 2012

History of TB policy shows need for care, investment equity in developed, developing countries

In a 200th anniversary article for the New England Journal of Medicine, Salmaan Keshavjee of the Department of Global Health and Social Medicine at Harvard Medical School and Paul Farmer of Partners in Health "seek to elucidate the reasons for the anemic response to drug-resistant tuberculosis [TB] by examining the recent history of tuberculosis policy," they write.

7 Sep 2012

UEA, IFR to study protective effects of broccoli consumption against prostate cancer

The Prostate Cancer Foundation is providing $1M of funding to the Institute of Food Research and the University of East Anglia (UEA) to study the protective effects of broccoli consumption against prostate cancer.

6 Sep 2012

Alnylam announces complete results from ALN-RSV01 Phase IIb trial on RSV infection

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today complete results from its Phase IIb trial with ALN-RSV01 for the treatment of respiratory syncytial virus (RSV) infection in lung transplant patients.

6 Sep 2012

Scientists identify three new genes associated with Primary Angle Closure Glaucoma

Singapore scientists have identified three new genes associated with Primary Angle Closure Glaucoma (PACG), a leading cause of blindness in Chinese people. PACG affects 15 million people worldwide, 80% of whom live in Asia.

5 Sep 2012

Scientists restore sense of smell in mice through gene therapy

Scientists have restored the sense of smell in mice through gene therapy for the first time -- a hopeful sign for people who can't smell anything from birth or lose it due to disease.

3 Sep 2012

DEAD-box proteins function as recycling nanopistons when unwinding RNA

AUSTIN, Texas-Molecular biologists at The University of Texas at Austin have solved one of the mysteries of how double-stranded RNA is remodeled inside cells in both their normal and disease states. The discovery may have implications for treating cancer and viruses in humans.

3 Sep 2012

Scientists create mathematical model that helps to design new drug cocktails against HIV

For years, doctors treating those with HIV have recognized a relationship between how faithfully patients take the drugs they prescribe, and how likely the virus is to develop drug resistance. More recently, research has shown that the relationship between adherence to a drug regimen and resistance is different for each of the drugs that make up the "cocktail" used to control the disease.

3 Sep 2012

The safety of trainee surgeons: an interview with Prof Calvin Coffey

Surgical training begins at an undergraduate medical student level where students are involved in operations to a minor degree, and educated using a combination of didactic and problem-based approaches.

31 Aug 2012

Studies examine how PML gene regulates the fatty acid oxidation pathway

Two papers led by scientific teams from the Cancer Genetics Program at Beth Israel Deaconess Medical Center (BIDMC) shed new light on the genetic mechanisms underlying cellular energy and metabolism and, at the same time, highlight both the challenges and opportunities of genetic approaches to cancer treatment.

31 Aug 2012

PD0325901 drug may hold potential to prevent neurofibromatosis 1 in children

A drug originally developed to stop cancerous tumors may hold the potential to prevent abnormal brain cell growth and learning disabilities in some children, if they can be diagnosed early enough, a new animal study suggests.

31 Aug 2012

UMHS, MidMichigan Health announce plans to affiliate as clinical and business partners

MidMichigan Health and the University of Michigan Health System have announced plans to affiliate as clinical and business partners.

29 Aug 2012

Gilead Sciences receives FDA approval for Stribild to treat HIV-1 infection

Gilead Sciences, Inc. announced today that the U.S. Food and Drug Administration (FDA) has approved Stribild (elvitegravir 150 mg/cobicistat 150 mg/emtricitabine 200 mg/tenofovir disoproxil fumarate 300 mg), a complete once-daily single tablet regimen for HIV-1 infection for treatment-naïve adults.

28 Aug 2012

Profilin-1 gene influences survival time in Lou Gehrig's disease

A team of scientists, including faculty at the University of Massachusetts Medical School (UMMS), have discovered a gene that influences survival time in amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease).

27 Aug 2012

$LCZ696 demonstrates beneficial effects in heart failure patients with preserved ejection fraction$

LCZ696 demonstrates beneficial effects in heart failure patients with preserved ejection fraction

The novel angiotensin receptor neprilysin inhibitor, LCZ696, demonstrated beneficial effects in heart failure patients with preserved ejection fraction (HFpEF), according to results of the PARAMOUNT (Prospective compArison of ARNI with ARB on Management Of heart failUre with preserved ejectioN fracTion) trial.

27 Aug 2012

Mexican-Americans with ancestral links have higher insulin resistance levels

Mexican-Americans with an ancestral link to Amerindian tribes were found to have higher insulin resistance levels, which is an indication of several chronic conditions such as type 2 diabetes, according to research by The University of Texas Health Science Center at Houston (UTHealth).

26 Aug 2012

Children more likely to pick up stomach infections from private water supplies

Children drinking from around half the UK's private water supplies are almost five times more likely to pick up stomach infections - according to research from the University of East Anglia (UEA).

26 Aug 2012

Personalized colon cancer therapy based on genetics of specific cancer

University of Minnesota Medical School and Masonic Cancer Center researchers have partnered with geneticists from Genentech, Inc., to discover how some proteins may cause the development of some forms of colon cancers.

24 Aug 2012

Pre-emptive therapy better than valacyclovir prophylaxis in treating CMV in transplant recipients

Waiting to treat the commonest viral infections in transplant recipients until they reach a certain threshold is better than prophylactically treating all recipients, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

24 Aug 2012

Medical School News and Research

Recent data from Silence Therapeutics’ Atu111 pre-clinical study on acute lung injury

Tight blood sugar control does not benefit pediatric patients undergoing heart surgery

History of TB policy shows need for care, investment equity in developed, developing countries

UEA, IFR to study protective effects of broccoli consumption against prostate cancer

Alnylam announces complete results from ALN-RSV01 Phase IIb trial on RSV infection

Scientists identify three new genes associated with Primary Angle Closure Glaucoma

Scientists restore sense of smell in mice through gene therapy

DEAD-box proteins function as recycling nanopistons when unwinding RNA

Scientists create mathematical model that helps to design new drug cocktails against HIV

The safety of trainee surgeons: an interview with Prof Calvin Coffey

Studies examine how PML gene regulates the fatty acid oxidation pathway

PD0325901 drug may hold potential to prevent neurofibromatosis 1 in children

UMHS, MidMichigan Health announce plans to affiliate as clinical and business partners

Gilead Sciences receives FDA approval for Stribild to treat HIV-1 infection

Profilin-1 gene influences survival time in Lou Gehrig's disease

LCZ696 demonstrates beneficial effects in heart failure patients with preserved ejection fraction

Mexican-Americans with ancestral links have higher insulin resistance levels

Children more likely to pick up stomach infections from private water supplies

Personalized colon cancer therapy based on genetics of specific cancer

Pre-emptive therapy better than valacyclovir prophylaxis in treating CMV in transplant recipients

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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