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Anchor Therapeutics announces publication describing pepducin technology as novel approach to target GPCR

Anchor Therapeutics today announced the publication of new research in the Proceedings of the National Academy of Sciences USA. The paper describes the identification and characterization of a pepducin-based allosteric agonist that targets CXCR4, a chemokine G protein-coupled receptor found on hematopoietic stem cells and other bone marrow-derived cells.

9 Dec 2010

Expert panel explores how to engage pediatricians, primary care physicians in preventing childhood obesity

As the prevalence of childhood obesity approaches epidemic levels, physicians on the "front line" need to become more involved in obesity prevention and weight management to reverse this dangerous trend among their young patients. But several obstacles discourage pediatricians and other primary care physicians from taking a more active role in managing childhood obesity.

9 Dec 2010

AJPH publishes study on importance of preventive dental treatment for pregnant women

Aetna today announced that the study, An Examination of Periodontal Treatment, Dental Care and Pregnancy Outcomes in an Insured Population, has been published online by the American Journal of Public Health.

9 Dec 2010

Organovo releases data on bioprinted blood vessels

Organovo, Inc., a regenerative medicine company focused on bioprinting technology, today announced the release of data on the first fully bioprinted blood vessels. Data was presented at the Tissue Engineering and Regenerative Medicine International Society (TERMIS) meeting in Orlando, Florida. The blood vessels were created through the use of the NovoGen MMX Bioprinter, Organovo's proprietary platform for the creation of 3D tissue constructs.

9 Dec 2010

Genetics in Medicine: Women who carry high-risk BRCA mutations opt for surgery

In women who test positive for BRCA 1/2 mutations associated with a high risk of breast or ovarian cancer, some key psychological factors influence the decision to undergo risk-reducing surgery, reports the December Genetics in Medicine, the official peer-reviewed journal of The American College of Medical Genetics.

8 Dec 2010

Rapid TB test endorsed by WHO

The World Health Organization (WHO) said that a new test that can detect tuberculosis (TB), including drug-resistant forms, in less than two hours could revolutionize treatment of the disease. Tuberculosis is still a major killer worldwide killing 4,700 people every day last year. The annual death toll of 1.7 million includes 380,000 people who are at particular risk because they have HIV, the virus that depresses the immune system and causes Aids.

8 Dec 2010

ChipDX validates genetic signature for early-stage colon cancer

ChipDX LLC, a New York-based online molecular diagnostics and personalized medicine company, discovered and validated a genetic signature for early-stage colon cancer and is developing an online screening application to enable clinicians to more accurately identify risk of recurrence. In the study, published in the December issue of the British Journal of Cancer, ChipDX demonstrates how the 163-gene signature stratifies colon cancer patients into high- and low-risk groups for recurrence with greater accuracy than current methods.

8 Dec 2010

Low and high vitamin D levels may increase frailty in older women

A recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM) found that lower and higher vitamin D levels were associated with an increased likelihood of frailty in older women. Women with vitamin D levels between 20.0 and 29.9 ng/ml were at the lowest risk of frailty.

8 Dec 2010

New Hora de Hablar CARDIO program launched to help better manage heart health

An innovative new program, Hora de Hablar CARDIO – Creando la Atencion Real y Dialogo Inmediato en la Oficina, launched today to encourage patients and health care professionals to actively partner to help better manage heart health through more productive conversations during medical visits.

8 Dec 2010

TOS, OAC call on FDA to address urgent need for obesity treatments

The Obesity Society (TOS) and the Obesity Action Coalition (OAC) today called on the Food and Drug Administration (FDA) to consider the urgent need for more tools to address the obesity epidemic facing more than 93 million Americans as they convene an advisory panel to review a new treatment for obesity.

8 Dec 2010

Lung transplant saves economist from near-lethal bout of swine flu

According to the critical care experts at The Johns Hopkins Hospital who treated him, Allen Bagents, 24, of Arlington, Va., is the least likely person anyone ever expects to get sick, let alone suffer a six-week, potentially fatal bout with the swine flu, better known as H1N1 influenza.

8 Dec 2010

AMGA, AMGF announce grantees in COPD Best Practices Learning Collaborative

The American Medical Group Association (AMGA) and the American Medical Group Foundation (AMGF) today announced recipients of grants for quality improvement initiatives focusing on care management for patients with Chronic Obstructive Pulmonary Disease (COPD). Recipients are medical groups, IPAs, academic practices, and integrated delivery systems that responded to a request for proposals distributed in August 2010.

8 Dec 2010

Robots in the ER

A group of computer engineers at Vanderbilt University is convinced that the basic technology is now available to create robot assistants that can perform effectively in the often-chaotic environment of the emergency room. The specialists in emergency medicine at Vanderbilt University Medical Center are enthusiastic about the potential advantages. So, the two groups have formed an interdisciplinary team to explore the use of robotics in this critical and challenging setting.

8 Dec 2010

Low-dose diazepam with NS-398 combination has twice the neuroprotective effect of NS-398 alone

Status epilepticus, prolonged seizures, can lead to significant neurological deficits and, rarely, even death. The anticonvulsant diazepam, a first line therapy for the condition, is neuroprotective when administered in high doses within two hours from seizure onset. Researchers at the 64th AES Annual Meeting now report that the combination of low-dose diazepam and NS-398, a COX-2 inhibitor, has twice the neuroprotective effect of NS-398 alone.

8 Dec 2010

Exertional heat-related injuries also occur during everyday activities

A new study conducted by researchers at the Center for Injury Research and Policy of The Research Institute at Nationwide Children's Hospital examined exertional heat-related injuries that were treated in emergency departments between 1997 and 2006. Exertional heat-related injuries are injuries that occur as a result of exercise or physical activity during warm or hot temperatures.

8 Dec 2010

OPRN collects samples from infants, mothers and fathers to reduce preterm birth complications

Every year, more than 50,000 babies are born premature in the United States. Despite the notable advances in neonatal care, these premature infants often suffer from preterm birth complications - the single largest cause of infant mortality. In order to better understand preterm birth, Nationwide Children's Hospital and The Ohio State University Medical Center (OSUMC) have partnered to form the Ohio Perinatal Research Network (OPRN).

8 Dec 2010

Video games effective in improving diet behaviors of children

Obesity in youngsters has risen dramatically in recent decades. Fruit and vegetable (FV) consumption and increased water intake can lower the risk of obesity, as can increased physical activity, but it is not always easy to convince children to eat better and exercise more. In a new study published in the January 2011 issue of the American Journal of Preventive Medicine, researchers found that video games designed to encourage these behaviors were effective.

8 Dec 2010

Some progress, but big challenges remain in prevention of cardiovascular disease

'Some progress, but the big challenges remain'. This was the verdict after the European Society of Cardiology (ESC) hosted the 2010 European Summit on CVD Prevention on 30 November. The summit was attended by a broad cross-section of medical experts, healthcare organisations, national societies, regulators and representatives from the European Union (EU).

8 Dec 2010

New research indicates that older women can deliver healthy babies

Career women who put babies on hold until after 40, or even 45, will be reassured by new research from Tel Aviv University. Even though there are associated risks for babies when postponing child-bearing, the neonates can overcome them, says Prof. Yariv Yogev of Tel Aviv University's Sackler School of Medicine and the Hospital for Women at Rabin Medical Center.

8 Dec 2010

New approach points towards effective stem cell therapies for spinal cord injury

Initial experiments suggest a possible new approach to stem cell therapy for spinal cord injuries—using biocompatible "channels" made of chitosan to guide regeneration of new spinal cord tissue, reports the December issue of Neurosurgery, official journal of the Congress of Neurological Surgeons.

8 Dec 2010