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Jefferson scientists receive grant to study genetics of platelet gene expression

Scientists at Jefferson Medical College have received a four-year, $3 million National Institutes of Health grant funded by the National Heart, Lung and Blood Institute to study variations of platelet function, specifically, the genetics of platelet gene expression. The study aims to find data that can be translated into novel therapeutic strategies and develop better predictors of cardiovascular disease.

30 Aug 2010

Promising skin cancer drug in the near horizon

A new drug has been developed to combat a deadly form of skin cancer – melanoma. The drug, PLX4032, was tested on 32 melanoma patients who had a key mutation in their tumors. 26 of these patients responded favorably says the study published in the New England Journal of Medicine.

30 Aug 2010

MEND 7-13 Program improves obesity management in children

The MEND 7-13 Program today announced statistically significant results from 2009/2010 US Community Implementation Data. This preliminary data is the first to come from a US population and is further evidence that programs achieve positive outcomes and are welcomed by communities.

30 Aug 2010

New high throughput sequencing technology to identify genetic defects in rare diseases

The majority of rare diseases are hereditary. But despite significant progress in genome research, in most cases their exact cause remains unclear. The discovery of the underlying genetic defect is, however, a prerequisite for their definitive diagnosis and the development of innovative approaches to their treatment. Scientists at the Max Planck Institute for Molecular Genetics and the Institute of Medical Genetics at the Charit- Universit-tsmedizin - Berlin have succeeded in using a new process with which all of the genes in the human genome can be analysed simultaneously.

30 Aug 2010

Misuse of OTC medicines increases risk for children

Many children are being put at risk by parents over-use of widely available over the counter (OTC) medicines for fever, coughs and colds, says a study from Australia to be presented to the annual conference of the International Pharmaceutical Federation (FIP) today (Monday 30 August).

30 Aug 2010

GWAS finds new genetic link between Parkinson's disease and inflammation

A hunt throughout the human genome for variants associated with common, late-onset Parkinson's disease has revealed a new genetic link that implicates the immune system and offers new targets for drug development.

30 Aug 2010

International conference to address clinical research in Europe

Journalists are invited to attend the one-day conference on the "Future of independent academic clinical research in Europe", which is being organised under the auspices of the Belgian Presidency of the European Union and with support of both the academies of medicine in Brussels.

30 Aug 2010

Authorities arrest more than 80 people, seize 10 tons of counterfeit meds in E. Africa

Authorities have arrested more than 80 people and seized 10 tons of counterfeit medicines across six East African countries, the international police agency Interpol announced Thursday, United Press International reports (8/26).

27 Aug 2010

Cigarettes as mood enhancers increase risk of depression

While some teenagers may puff on cigarettes to 'self-medicate' against the blues, scientists at the University of Toronto and the University of Montreal have found that smoking may actually increase depressive symptoms in some adolescents. Published in the journal Addictive Behaviors, the findings are part of the long-term Nicotine Dependence in Teens (NDIT) study based at the University of Montreal Hospital Research Centre.

27 Aug 2010

Issues in primary care: Medical homes and ethical concierge practices

News outlets report on trends in the primary care workforce, including medical homes and concierge medicine.

27 Aug 2010

Recent releases in Global Health

"[N]ew diagnostic techniques [for tuberculosis] need to be studied in children," according to a Lancet Infectious Diseases Reflection. "Tuberculosis is an important cause of morbidity and mortality in children worldwide, but estimates of disease burden are inaccurate because most cases are not confirmed," the author writes. He discusses a study published in the same issue that examines various methods for diagnosing TB in children.

27 Aug 2010

Montana Gov. seeks cheaper drugs for residents; Legal immigrants may lose health insurace in Mass.

The Associated Press: "Gov. Brian Schweitzer, cooking up a new plan to get cheaper prescription drugs for state residents, said he wants to let every Montanan get discounted medicine through Medicaid." It's his most recent idea about how "to either import cheaper name-brand prescriptions or to otherwise bypass what he sees as exorbitant prices charged by 'drug cartels.'"

27 Aug 2010

Fosun Pharma increases investment in Chindex

Chindex International, Inc., a leading independent American provider of Western healthcare products and services in the People's Republic of China, and Shanghai Fosun Pharmaceutical (Group) Co., Ltd., a leading manufacturer and distributor of western and Chinese medicine and devices in China, today announced that they have consummated a previously-announced stock sale.

27 Aug 2010

Transcatheter heart valve replacement recipient celebrates 102nd birthday

When Doris Snyder celebrated her 102nd birthday on August 10, she was that much closer to the expected birth of her first great-granddaughter who's due to arrive early September. She is very excited about the milestone, which might not have been possible were it not for a cutting-edge, experimental procedure that replaced one of Doris' heart valves weeks earlier when she was 101. The valve had been rendered useless by aortic valve stenosis—hardening from calcium deposits that restrict the flow of blood from the heart.

27 Aug 2010

Research Roundups: Underinsured children; Hospital progress on electronic records; Federal officlals' work on comparative effectiveness

Underinsurance Among Children In The United States - This study examines the scope of underinsurance, or health insurance that fails to sufficiently meet the needs, of children living in the U.S. Based on information obtained from the 2007 National Survey of Children's Health, the authors of the study report, "19.3% — or 14.1 million — of all U.S. children (and 22.7% of children with continuous insurance coverage) were underinsured in 2007, exceeding the number of children without any insurance at all during the year (3.4 million) and the number who had insurance during only part of the year (7.6 million)."

27 Aug 2010

FDA approves Novartis' Tekamlo for treatment of high blood pressure

The US Food and Drug Administration (FDA) approved Tekamlo™ (aliskiren and amlodipine) tablets, a single-pill for the treatment of high blood pressure combining the only approved direct renin inhibitor, Tekturna® (aliskiren), with the widely used calcium channel blocker amlodipine. Tekamlo is approved as initial therapy for patients who are likely to need multiple drugs to achieve their blood pressure goals, and as replacement therapy for patients whose blood pressure is not adequately controlled with either aliskiren or amlodipine alone.

27 Aug 2010

Elsevier, KIT sign MoU to provide developing country researchers access to ScienceDirect and Scopus

Elsevier and the Royal Tropical Institute (KIT) in Amsterdam announced on 26th of August the signing of a Memorandum of Understanding (MoU) providing 150 researchers working in least-developed and low-income countries (for example Benin, Mozambique, Ethiopia, Togo etc.) with access to ScienceDirect and Scopus, Elsevier's online scientific research platform and flagship abstract and citation database.

27 Aug 2010

APF offers actionable solutions to improve access to pain care

The American Pain Foundation (APF), the nation's largest consumer advocacy organization for people in pain, released today a position statement imploring the medical community, regulators and concerned stakeholders to reaffirm their ethical commitment to the 76.5 million Americans—or one in four people—who struggle with pain, work collaboratively to improve access to pain care and dismantle the barriers preventing timely, appropriate and effective pain care for millions.

27 Aug 2010

First Edition: August 27, 2010

In the headlines today, news about U.S. plans to step up efforts to crack down on health care fraud.

27 Aug 2010

Viking Systems to present Next Generation 3DHD technology at 5th ISHAC

Viking Systems, Inc. announced today that it will present its Next Generation 3DHD technology at the 5th International Symposium on Hybrid Approach to Congenital Heart Disease (ISHAC) from August 31 - September 2, 2010 in Columbus, Ohio.

27 Aug 2010