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Scientists identify enzyme mutations in AML patients

A study published online on February 8 in the Journal of Experimental Medicine (www.jem.org) reports that several distinct mutations found in a subset of patients with acute myelogenous leukemia (AML) result in excess production of the same metabolite.

9 Feb 2010

KineMed, Bristol-Myers Squibb broaden collaboration to develop novel mechanisms for Alzheimer’s disease

KineMed, Inc. a translational and personalized medicine development company, today announced a broadening of its collaboration with Bristol-Myers Squibb Company (NYSE: BMY) in the area of Alzheimer’s disease and other neurodegenerative conditions.

9 Feb 2010

Doctors do not follow evidence-based guidelines for treating low back pain, says report

Australian general practitioners often treat patients with low back pain in a manner that does not appear to match the care endorsed by international clinical guidelines, according to a report in the February 8 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

9 Feb 2010

NIH awards over $15M for Tulane University's collaborative effort to combat VHF

Corgenix Medical Corporation, a worldwide developer and marketer of diagnostic test kits, and Tulane University, today announced a major extension of the collaborative effort to combat viral hemorrhagic fever (VHF), an effort that will generate an additional $800,000 in contract revenue for Corgenix over the life of the contract.

9 Feb 2010

Researchers study link between premature births and cerebral palsy

Cerebral palsy (CP) has increased in infants born prematurely in the United States, according to data presented by researchers from Loyola University Health System (LUHS). These findings were reported at the 30th Annual Meeting of the Society for Maternal-Fetal Medicine in Chicago.

9 Feb 2010

Unhealthy behaviors contribute to excessive number of premature deaths in U.S.

The standard American diet, combined with inactivity and other unhealthy lifestyle behaviors, contributes to an excessive number of premature deaths in this country, according to leading preventive cardiology experts speaking at the American College of Cardiology's Fourth Annual Heart of Women's Health Conference in Washington, D.C.

9 Feb 2010

Poor handgrip strength linked to premature mortality, disability and other health complications in older people

Poor or declining handgrip strength in the oldest old is associated with poor survival and may be used as a tool to assess mortality, found an article in CMAJ (Canadian Medical Association Journal) (pre-embargo link only) http://www.cmaj.ca/embargo/cmaj091278.pdf. The fastest growing segment of the elderly population is the group older than 85 years, classified as the oldest old.

9 Feb 2010

ebrary introduces new subscription database in Medical Technology

Health care companies that design and manufacture medical devices, equipment, and instruments can now help their technologists, engineers, and other employees conduct research more efficiently and effectively, resulting in greater cost savings and faster development times for new products.

9 Feb 2010

Dana-Farber Cancer Institute and Sanford-Burnham Medical Research Institute sign license agreement with Genentech

Dana-Farber Cancer Institute and the Sanford-Burnham Medical Research Institute have signed a license agreement with Genentech, a wholly owned member of the Roche group, and Roche, that grants the companies exclusive rights to manufacture, develop and market human monoclonal antibodies to treat and protect against group 1 influenza viruses. These viruses include the strains for the current seasonal and H1N1 influenzas. Genentech and Roche also have a non-exclusive right to manufacture, develop and market diagnostic tests for group 1 influenza.

9 Feb 2010

Study indicates pain treatment may vary in Latino and white children post surgery

Differences might exist in the amount of pain medicine given to Latino and white children after surgery, found a new, small study in which Latino children received 30 percent less opioid analgesics (morphine or morphine-like drugs) than white children did.

9 Feb 2010

Journal highlights toxic nature of herbal medicines

A University of Adelaide forensic pathologist has sounded a worldwide warning of the potential lethal dangers of herbal medicines if taken in large quantities, injected, or combined with prescription drugs.

9 Feb 2010

Study indicates women receiving antiretroviral therapy are more likely to become pregnant

In PLoS Medicine this week a study conducted in a multi-country HIV treatment program in sub-Saharan Africa has found that pregnancy rates increase in HIV-infected women after they start antiretroviral therapy (ART).

9 Feb 2010

Positive data from Cara Therapeutics' peripherally-restricted kappa opioid agonist Phase II trial

Cara Therapeutics, Inc. today announced positive data in a Phase II proof-of-concept clinical trial of its peripherally-restricted kappa opioid agonist, CR845. The 46 patient Phase II, multi-center, double-blind, placebo-controlled study was conducted at eight hospitals in the United States and evaluated the efficacy and safety of CR845 in women following laparoscopic-assisted hysterectomy.

9 Feb 2010

Biocell Center participates in ‘Society for Maternal-Fetal Medicine’ meeting

Biocell Center announced today its further commitment to working with maternal-fetal-medicine doctors by attending the Society for Maternal-Fetal Medicine's (SMFM) annual meeting.

9 Feb 2010

Texas court case and Florida web site raise questions about effectiveness of physician oversight

A Texas court case reveals gaps in physician oversight, The New York Times reports. "It was beyond [Anne Mitchell's] conception that she would be indicted and threatened with 10 years in prison for doing what she knew a nurse must: inform state regulators that a doctor at her rural hospital was practicing bad medicine." Mitchell was first jailed in June and will stand trial this week for "misuse of official information, a third-degree felony in Texas," after reporting a physician for using unorthodox procedures - some of which went awry - and practicing in an operating room where he did not have privileges.

9 Feb 2010

Plant-produced antibodies can help prevent infection

The first head-to-head comparison of therapeutic monoclonal antibodies produced from plants versus the same antibodies produced from mammalian cells has shown that plant-produced antibodies can fight infection equally well.

9 Feb 2010

Genta commences Phase 2 trial of tesetaxel on first subject

Genta Incorporated announced that the Company has initiated treatment of the first subject in a new Phase 2 trial of tesetaxel in advanced melanoma. Tesetaxel is the Company’s newest clinical-stage small molecule. As a late Phase 2 oncology product, tesetaxel is the leading oral taxane currently in clinical development. The new trial builds on more than ten years of Genta’s experience in melanoma clinical research.

9 Feb 2010

A novel way to identify color choice in healthy, anxious and depressed individuals

People with anxiety and depression are most likely to use a shade of gray to represent their mental state. Researchers writing in the open access journal BMC Medical Research Methodology describe the development of a color chart, The Manchester Color Wheel, which can be used to study people's preferred pigment in relation to their state of mind.

9 Feb 2010

QIAGEN acquires global licence for PI3K gene to develop real-time-PCR and endpoint PCR assays

QIAGEN today announced that its wholly owned subsidiary DxS has acquired the global and exclusive licence for biomarker PI3K from Johns Hopkins University to develop real-time-PCR and endpoint PCR assays.

From QIAGEN Manchester Limited 8 Feb 2010

Mutation in alpha tectorin gene causes progressive childhood deafness

Deafness is the most common disorder of the senses. Tragically, it commonly strikes in early childhood, severely damaging an affected child's ability to learn speech and language. In many cases, children gradually lose their hearing to become profoundly deaf over a long period of months to years, but scientists know very little about how this progressive loss happens, making prospects for prevention and cure very slim.

8 Feb 2010

Medicine News and Research

Scientists identify enzyme mutations in AML patients

KineMed, Bristol-Myers Squibb broaden collaboration to develop novel mechanisms for Alzheimer’s disease

Doctors do not follow evidence-based guidelines for treating low back pain, says report

NIH awards over $15M for Tulane University's collaborative effort to combat VHF

Researchers study link between premature births and cerebral palsy

Unhealthy behaviors contribute to excessive number of premature deaths in U.S.

Poor handgrip strength linked to premature mortality, disability and other health complications in older people

ebrary introduces new subscription database in Medical Technology

Dana-Farber Cancer Institute and Sanford-Burnham Medical Research Institute sign license agreement with Genentech

Study indicates pain treatment may vary in Latino and white children post surgery

Journal highlights toxic nature of herbal medicines

Study indicates women receiving antiretroviral therapy are more likely to become pregnant

Positive data from Cara Therapeutics' peripherally-restricted kappa opioid agonist Phase II trial

Biocell Center participates in ‘Society for Maternal-Fetal Medicine’ meeting

Texas court case and Florida web site raise questions about effectiveness of physician oversight

Plant-produced antibodies can help prevent infection

Genta commences Phase 2 trial of tesetaxel on first subject

A novel way to identify color choice in healthy, anxious and depressed individuals

QIAGEN acquires global licence for PI3K gene to develop real-time-PCR and endpoint PCR assays

Mutation in alpha tectorin gene causes progressive childhood deafness

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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