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Blood vessel protein reverses macular degeneration, diabetic retinopathy in mice

Two major eye diseases and leading causes of blindness—age-related macular degeneration and diabetic retinopathy can be reversed or even prevented by drugs that activate a protein found in blood vessel cells, researchers at the University of Utah School of Medicine and several other institutions have announced in a new study.

17 Mar 2008

Toddlers affected most by secondhand smoke exposure at home

Secondhand smoke in the home appears to induce markers for heart disease as early as the toddler years, researchers reported at the American Heart Association's 48th Annual Conference on Cardiovascular Disease Epidemiology and Prevention.

14 Mar 2008

Next emerging disease will come from tropics, say scientists

Scientists from four well-known institutions say the next major disease like HIV/AIDS or SARS could occur in any of a number of developing countries concentrated along the equator.

14 Mar 2008

Finding in mice could help prevent common complications of kidney damage

Kidney damage often sets off a slew of complications in patients, spreading organ failure like wildfire throughout their bodies.

14 Mar 2008

Cancer drug allergies

Cancer patients from the Southeastern United States who are treated with the drug cetuximab, known commercially as Erbitux, are far more likely to suffer severe allergic reactions than patients in other regions of the country.

14 Mar 2008

Simple laboratory test predicts risk of kidney injury after surgery

A simple laboratory test may provide a new way for doctors to identify patients at risk of developing potentially severe acute kidney injury (AKI) after surgery up to three days before the problem would otherwise be detected, reports a pilot study in the May 2008 issue of the Clinical Journal of the American Society of Nephrology .

14 Mar 2008

Low cost tactics improve medication use after heart attack

Direct-to-patient communication about the importance of continuing prescription drug treatment after a heart attack is a simple, low-cost way to increase the likelihood of patients adhering to life saving therapies at least four out of every five days.

14 Mar 2008

Chronic sleep disruption can cause heart and kidney disease

Chronic sleep disruption can cause heart and kidney disease, researchers at the Peter Munk Cardiac Centre of the Toronto General Hospital have discovered.

14 Mar 2008

Is deep-vein thrombosis lurking in your legs?

They kill 300,000 people a year - but most of them could be prevented. They strike more than a million people every year, most of them out of the blue - and half without causing symptoms.

14 Mar 2008

Heavier alcohol consumption increases the risk of esophageal squamous cell carcinoma

Heavier alcohol consumption increases the risk of esophageal squamous cell carcinoma (ESCC). There are synergetic interactions among alcohol drinking and ALDH2, ADH1B, CYP2E1 genotypes.

14 Mar 2008

After-school programs can increase physical activity of adolescent girls

Afterschool programs can modestly increase the amount of physical activity among girls in middle school, according to new results from the Trial of Activity for Adolescent Girls (TAAG), a multiple site, community based study supported by the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health.

14 Mar 2008

Researchers find benefit for lymphoma patients in combined PET-CT scanning

Combined positron emission tomography (PET) and computed tomography (CT) imaging of lymphoma patients is a more effective method to evaluate response to radiation therapy, and may help patients avoid unnecessary follow-up treatments, a study by researchers at the University of Southern California (USC) suggests.

13 Mar 2008

Researchers find cause of severe allergic reaction to cetuximab

Clinicians have been perplexed by the fact that some patients given the drug cetuximab - an immune-based therapy commonly used to treat persons diagnosed with head and neck cancer, or colon cancer - have a severe and rapid adverse reaction to the drug.

13 Mar 2008

Research could put penicillin back in battle against antibiotic resistant bugs

Research led by the University of Warwick has uncovered exactly how the bacterium Streptococcus pneumoniae has become resistant to the antibiotic penicillin.

13 Mar 2008

Protein deficiency leads to faster fat burning in mice, study shows

Researchers have developed a new, lean mouse with characteristics suggesting that someday, using medication to manipulate a specific protein in humans could emerge as a strategy to treat obesity and disorders associated with excess weight, such as diabetes and metabolic syndrome.

13 Mar 2008

Preschoolers benefit from daycare program to prevent obesity

A preschool-based intervention program helped prevent early trends toward obesity and instilled healthy eating habits in multi-ethnic 2- to 5-year-olds, according to a report presented at the American Heart Association's Conference on Nutrition, Physical Activity and Metabolism.

13 Mar 2008

Obesity bottlenecks cellular power plant

The machinery responsible for energy production in fat cells is working poorly as a result of obesity.

13 Mar 2008

Discovery could lead to much-needed kidney failure treatment

The unwanted activation of an important cell-signaling pathway may play a role in two kidney problems that are major causes of end-stage renal disease, scientists at the Albert Einstein College of Medicine of Yeshiva University have found.

13 Mar 2008

Some teenagers spending 30 hours a week in front of television and computer screens

While most teenagers (60 percent) spend on average 20 hours per week in front of television and computer screens, a third spend closer to 40 hours per week, and about 7 percent are exposed to more than 50 hours of 'screen-time' per week, according to a study presented at the American Heart Association's 48th Annual Conference on Cardiovascular Disease Epidemiology and Prevention.

13 Mar 2008

Aerosol vaccine provides low-cost, needle-free TB treatment

A novel aerosol version of the most common tuberculosis (TB) vaccine, administered directly to the lungs as an oral mist, offers significantly better protection against the disease in experimental animals than a comparable dose of the traditional injected vaccine, researchers report this week in the Proceedings of the National Academy of Sciences.

13 Mar 2008