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Researchers advance stem cell gene therapy

Ireland Cancer Center of University Hospitals Case Medical Center researchers have recently made great strides in stem cell gene therapy research by transferring a new gene to cancer patients, via their own stem cells, with the ultimate goal of being able to use stronger chemotherapy treatment with less severe side effects.

13 Dec 2007

Intensive care quality of sleep improved by new drug dexmedetomidine

A new sedative drug has been shown to improve the sleep quality and comfort levels of intensive care patients, compared to the most commonly-used medication, according to research published today in the journal JAMA.

13 Dec 2007

Immune compound blocks virus' ability to hijack antibodies

Researchers at Washington University School of Medicine in St. Louis have shown that a controversial phenomenon known as antibody-dependent enhancement (ADE) of infection is suppressed by C1q, a blood-borne immune system compound.

13 Dec 2007

GlaxoSmithKline response to JAMA article on ICES retrospective analysis

The following is GlaxoSmithKline's response to the retrospective analysis by the Institute for Clinical Evaluative Sciences (ICES) titled "Thiazolidinediones and Cardiovascular Outcomes in Older Patients with Diabetes".

13 Dec 2007

Geriatric care intervention appears to provide some benefits for low-income seniors

A home-based geriatric care program for low-income seniors resulted in higher-quality medical care, improvement in quality of life and fewer emergency department visits, but did not appear to prevent decline in physical functioning, according to a study in the December 12 issue of JAMA: The Journal of the American Medical Association.

13 Dec 2007

Variant of a tumor suppressor gene associated with aggressive prostate cancer

A variant of a tumor suppressor gene may be associated with an increased risk of aggressive prostate cancer, according to a study published online December 11 in the Journal of the National Cancer Institute.

13 Dec 2007

Crimean Congo hemorrhagic fever virus strips away immune system's defensive measures

When the alert goes out that a virus has invaded the body, cells that have yet to be attacked prepare by "armoring" themselves for combat, attaching specific antiviral molecules to many of their own proteins to help resist the invader.

13 Dec 2007

Cancer stem cells may be cause of brain tumors

Expert available for comment on "Cancer Stem Cells" symposium at American Society of Hemotology (ASH) meeting, led by Dr. Andrew Schafer, chairman of medicine, NewYork-Presbyterian/Weill Cornell, and president, ASH.

13 Dec 2007

Improving health care for older adults

Most older adults obtain their health care in the offices of busy primary care physicians or, in the case of those without physicians, in even busier hospital emergency departments.

13 Dec 2007

New UK Centre for Zoonosis Research to open in Liverpool

The UK's National Centre for Zoonosis Research, dedicated to the study of animal-borne human diseases, will be opened at the University of Liverpool.

12 Dec 2007

Scientists seek to assess the microbial risks in the water we drink

It is a familiar scenario experienced around the world: an outbreak of gastrointestinal illness suddenly emerges in a community, and no one knows where it came from or how to stop it. At the start of the outbreak, only a few people are affected, most often the very old and the very young.

12 Dec 2007

Better health outcomes in hospitals using information technology

Patients are more likely to have better health outcomes if they are treated at hospitals using information technology (IT) systems, according to a comprehensive new Florida State University study.

12 Dec 2007

Exercise testing to predict mitral regurgitation

In as many as one in five people over age 55, when the heart contracts to send blood around the body, some degree of backward leakage occurs across the mitral valve, a condition known as mitral regurgitation (MR).

12 Dec 2007

Human hormone shows potential as new antidepressant agent

Novel treatment strategies for major depression with broader treatment success or a more rapid onset of action would have immense impact on public health, a new study published in the December 1st issue of Biological Psychiatry explains.

12 Dec 2007

Kids more active when playground well equipped

Children play harder and longer when their child-care centers provide portable play equipment such as balls and jump ropes, more opportunities for active play and physical activity training and education for staff and students, according to researchers at the University of North Carolina at Chapel Hill School of Public Health.

12 Dec 2007