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First genome sequence of XDR strain of the bacterium Mycobacterium tuberculosis

An international collaboration led by researchers in the US and South Africa today announced the first genome sequence of an extensively drug resistant (XDR) strain of the bacterium Mycobacterium tuberculosis, one linked to more than 50 deaths in a recent tuberculosis (TB) outbreak in KwaZulu-Natal, South Africa.

21 Nov 2007

New model to predict the spread of emerging diseases

A new model to predict the spread of emerging diseases has been developed by researchers in the US, Italy, and France.

21 Nov 2007

Oral drug sets a new survival standard for bone marrow cancer

Findings from two large, international clinical trials show "unprecedented" survival for patients with multiple myeloma, a blood cancer that occurs in the blood-making cells of bone marrow.

21 Nov 2007

Pediatric pediatric pulmonary expert comments on study of lung transplants for cystic fibrosis

Commenting on a study of lung transplantation for children with cystic fibrosis, a leading pediatric pulmonologist calls the study “startling” in an editorial in this week's New England Journal of Medicine that accompanies the study.

21 Nov 2007

New discoveries about nitric oxide can provide drugs for schizophrenia

Problems with memory and social function in patients with schizophrenia may result from an imbalance in the brain’s nitric oxide system.

21 Nov 2007

Lung transplants do more harm than good to children with cystic fibrosis

Lung transplantation, the therapy almost every cystic fibrosis patient (CF) considers at some point to prolong survival, rarely helps children with the disease live longer and, in fact, often increases their risk of dying, University of Utah researchers conclude in the most extensive study of the issue to date.

21 Nov 2007

GlaxoSmithKline to acquire Reliant Pharmaceuticals

GlaxoSmithKline and Reliant Pharmaceuticals Inc. have announced that they had reached an agreement under which Reliant will be acquired by GSK for $1.65 billion (800 million pounds Sterling) in cash.

21 Nov 2007

Moderate, long-term pain medication use does not impair a person's ability to drive safely

Moderate, long-term pain medication use does not impair a person's ability to drive safely, according to a study by Dr. Asokumar Buvanendran, associate professor, Department of Anesthesiology at Rush University Medical Center, Chicago.

21 Nov 2007

Lenalidomide - dexamethasone combination effective against multiple myeloma

Pairing a new thalidomide derivative with a steroid slows progress of multiple myeloma, an incurable bone marrow cancer, and prolongs the lives of patients who have relapsed from previous treatment, researchers report in the Nov. 22 New England Journal of Medicine.

21 Nov 2007

Sleep apnea and driving

Obstructive Sleep Apnea (OSA) is a disease that not many people know about although they may even suffer from it.

21 Nov 2007

Measures that are needed to curb humanity's most fatal diseases

Several of the world's most eminent health scientists and organizations today publish a landmark global consensus on the 20 foremost measures needed to curb humanity's most fatal diseases, their study featured in Nature magazine.

21 Nov 2007

Study looks at effects of smoking and breathing second-hand smoke along with drinking

Tobacco smoke-filled air is bad for cardiovascular health, and drinking alcohol at the same time only makes it worse, according to researchers at the University of Alabama at Birmingham (UAB).

21 Nov 2007

New technique provides stem cells without ethical and legal constraints

In a paper to be published Nov. 22 in the online edition of the journal Science, a team of University of Wisconsin-Madison researchers reports the genetic reprogramming of human skin cells to create cells indistinguishable from embryonic stem cells.

21 Nov 2007

Human pluripotent stem cells without human cloning

Two major scientific papers published this week in Science and Cell unveil a proven way to generate patient-matched human pluripotent stem cells without human cloning, and without the use of human embryos or human or animal eggs.

21 Nov 2007

Japanase scientists reprogramme human adult cells to function like pluripotent embryonic stem cells

Acclaimed stem cell researcher Shinya Yamanaka, MD, PhD, has reported that he and his Kyoto University colleagues have successfully reprogrammed human adult cells to function like pluripotent embryonic stem (ES) cells.

21 Nov 2007

Study looks at rural and urban cancer patients in terms of late-stage presentation

Rural patients are often assumed to be the top truants in American medicine, not seeking medical attention until a condition is more advanced and less treatable.

21 Nov 2007

Whole-body positron emission tomography can reassure cervical cancer patients

Whole-body PET (positron emission tomography) scans done three months after completion of cervical cancer therapy can ensure that patients are disease-free or warn that further interventions are needed, according to a study at Washington University School of Medicine in St. Louis.

21 Nov 2007

Monkeys fend off AIDS-like symptoms with enhanced HIV vaccine

Researchers at the University of Pennsylvania School of Medicine have discovered that using an immune system gene to enhance a vaccine used to study HIV in macaque monkeys provides the animals with greater protection against simian HIV (SHIV) than an unmodified vaccine.

21 Nov 2007

Older people who live alone more likely to be unhappy

Older people living alone are more likely to be depressed, lonely and unhappy and to be less satisfied with life than those living with others, according to new research.

21 Nov 2007

FDA clears Veridex test for the monitoring of metastatic colorectal cancer

Veridex, LLC has announced that the U.S. Food and Drug Administration (FDA) has granted an expanded clearance for the CellSearch System to be used as an aid in the monitoring of metastatic colorectal cancer.

21 Nov 2007