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Researchers elucidate how a single mutation causes episodic ataxia type 6

Worldwide, only a handful of patients are known to suffer from episodic ataxia type 6, a neurological disease that causes transient loss of muscle control.

3 Apr 2023

Membrane attack complex could be a potential therapeutic target to slow or prevent AMD

A study from the National Eye Institute (NEI) identified rare genetic variants that could point to one of the general mechanisms driving age-related macular degeneration (AMD), a common cause of vision loss in older adults.

3 Apr 2023

The association between regular glucosamine use and risk of dementia

Researchers assessed the association between daily glucosamine consumption and the risk of new-onset dementia.

3 Apr 2023

Lipid Nanoparticles (LNPs) and DNA delivery – unlocking the future of medical research

In this interview, Kate Stumpo speaks to Michael Girgis about Lipid nano particles, and the future of the field.

From Bruker Life Sciences Mass Spectrometry 31 Mar 2023

POSTECH team engineers an artificial kidney for early detection of adverse drug reactions

The kidney plays a vital role in maintaining homeostasis within the body by eliminating toxic and superfluous substances in the bloodstream, including waste generated during metabolic processes, through urine.

31 Mar 2023

New insights and emerging disease-modifying drugs for Alzheimer’s disease treatment

A recent review published in Biochemical Pharmacology summarized the ongoing research, providing insights into pathophysiology and emerging drugs for Alzheimer’s disease (AD).

31 Mar 2023

Utilizing a molecular syringe for the delivery of functional proteins into human cells with high efficiency

Researchers investigated the feasibility of utilizing a bacterial contractile injection system for programmable protein delivery.

31 Mar 2023

New structural details of the COVID-19 virus revealed

A new study led by Worcester Polytechnic Institute (WPI) brings into sharper focus the structural details of the COVID-19 virus, revealing an elliptical shape that "breathes," or changes shape, as it moves in the body.

30 Mar 2023

New type of nanoparticle can deliver messenger RNA encoding useful proteins to the lungs

Engineers at MIT and the University of Massachusetts Medical School have designed a new type of nanoparticle that can be administered to the lungs, where it can deliver messenger RNA encoding useful proteins.

30 Mar 2023

Study indicates interleukin-6-dependant pathway dysregulation as a key druggable feature of COVID-19

Researchers identified an interleukin 6 dependent alternative pathway as a therapeutic strategy against coronavirus disease 2019.

30 Mar 2023

The emergence of lateral flow assays in diagnostics

In this interview, News-Medical talks to Hasret Altan-Martin from Sartorius about the ongoing emergence of lateral flow assays in diagnostics.

From Sartorius Lab Instruments GmbH & Co. KG 29 Mar 2023

NPC1L1-EGFP mice enable researchers to fluorescently visualize, evaluate vesicular endocytosis

Excessive cholesterol absorption from intestinal lumen contributes to the pathogenesis of hypercholesterolemia, which is a well-established risk factor for atherosclerotic cardiovascular disease.

28 Mar 2023

Pneumolysin toxin holds promise for developing therapies against Streptococcus pneumoniae

In a recent study published in the journal PLoS ONE, researchers in Spain performed a systematic review of pneumolysin (PLY) toxin as a molecular target to develop novel therapeutics against Streptococcus pneumoniae.

27 Mar 2023

Dormant cone photoreceptors in the degenerating retina may retain visual function, research suggests

New UCLA research in mice suggests that "dormant" cone photoreceptors in the degenerating retina are not dormant at all, but continue to function, producing responses to light and driving retinal activity for vision.

27 Mar 2023

Researchers discover a new role for one of the genes linked to hereditary spastic paraplegia

Researchers from the University of Seville and the Seville Institute of Biomedicine (IBiS), in collaboration with the University of Cambridge, have identified a new role for one of the genes related to hereditary spastic paraplegia.

27 Mar 2023

New technology can rapidly analyze the metabolic state of lipids in cells

Professor Itaru Hamachi, Lecturer Tomonori Tamura, and Assistant Professor Masaki Tsuchiya of Kyoto University have developed a new technology called O-ClickFC (Organelle-selective click labeling with flow cytometry), which can, at a very high speed, analyze the metabolic state of lipids in cells.

27 Mar 2023

Tulane receives up to $16 million to move nasal pneumonia vaccine from the lab to clinical trials

The National Institute of Allergy and Infectious Diseases awarded an up to $16 million contract to Tulane University to bring to phase one clinical trial a nasal spray vaccine university researchers invented to thwart antibiotic-resistant Klebsiella pneumoniae, a leading cause of pneumonia.

24 Mar 2023

Candida auris escapes innate immunity through metabolic reprogramming

A team of scientists from Australia and Israel demonstrates that Candida auris, a fungus associated with life-threatening and drug-resistant infections, escapes the host's innate immune response by destroying macrophages through metabolic reprogramming. The fungus is also capable of escaping antimicrobial inflammatory response.

23 Mar 2023

Psychological therapy can help provide better quality of life for women with endometriosis

Nearly 10% of Danish women suffer from endometriosis, which can cause serious pelvic pain.

23 Mar 2023

Low-cost, universal oral COVID-19 vaccine prevents severe respiratory illness in hamsters

A UCLA-led team has developed an inexpensive, universal oral COVID-19 vaccine that prevented severe respiratory illness and weight loss when tested in hamsters, which are naturally susceptible to SARS-CoV-2.

22 Mar 2023

Membrane News and Research

Researchers elucidate how a single mutation causes episodic ataxia type 6

Membrane attack complex could be a potential therapeutic target to slow or prevent AMD

The association between regular glucosamine use and risk of dementia

Lipid Nanoparticles (LNPs) and DNA delivery – unlocking the future of medical research

POSTECH team engineers an artificial kidney for early detection of adverse drug reactions

New insights and emerging disease-modifying drugs for Alzheimer’s disease treatment

Utilizing a molecular syringe for the delivery of functional proteins into human cells with high efficiency

New structural details of the COVID-19 virus revealed

New type of nanoparticle can deliver messenger RNA encoding useful proteins to the lungs

Study indicates interleukin-6-dependant pathway dysregulation as a key druggable feature of COVID-19

The emergence of lateral flow assays in diagnostics

NPC1L1-EGFP mice enable researchers to fluorescently visualize, evaluate vesicular endocytosis

Pneumolysin toxin holds promise for developing therapies against Streptococcus pneumoniae

Dormant cone photoreceptors in the degenerating retina may retain visual function, research suggests

Researchers discover a new role for one of the genes linked to hereditary spastic paraplegia

New technology can rapidly analyze the metabolic state of lipids in cells

Tulane receives up to $16 million to move nasal pneumonia vaccine from the lab to clinical trials

Candida auris escapes innate immunity through metabolic reprogramming

Psychological therapy can help provide better quality of life for women with endometriosis

Low-cost, universal oral COVID-19 vaccine prevents severe respiratory illness in hamsters

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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