Membrane News and Research

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Phenoxodiol, an investigational drug shows promise for ovarian cancer

A new study further supports the unique mechanism of action of phenoxodiol, an investigational drug being studied for the treatment of ovarian cancer.

2 May 2007

Scientists find new way to analyze the moving parts of large proteins

Scientists from Baylor College of Medicine (BCM) and Rice University have discovered a new way to analyze the moving parts of large proteins , a breakthrough that will make it easier for structural biologists to classify and scrutinize the active sites of proteins implicated in cancer and other diseases.

1 May 2007

Important step towards a spatially and temporally quantifiable model of the cell

Cell membranes are like two-dimensional fluids whose molecules are distributed evenly through lateral diffusion.

26 Apr 2007

Researchers find way to kill cystic fibrosis superbug, Burkholderia cenocepacia

Researchers from the Schulich School of Medicine & Dentistry at The University of Western Ontario , working with a group from Edinburgh, have discovered a way to kill the cystic fibrosis superbug, Burkholderia cenocepacia.

25 Apr 2007

Muscle restoration in an animal model of Duchenne muscular dystrophy

Using a new type of drug that targets a specific genetic defect, researchers at the University of Pennsylvania School of Medicine, along with colleagues at PTC Therapeutics Inc. and the University of Massachusetts Medical School, have for the first time demonstrated restoration of muscle function in a mouse model of Duchenne's muscular dystrophy (DMD).

24 Apr 2007

Potential therapeutic target for multiple sclerosis

Oregon Health & Science University neuroscientists are eyeing a protein as a potential therapeutic target for multiple sclerosis because de-activating it protects nerve fibers from damage.

24 Apr 2007

New approach to cystic fibrosis treatment

Researchers at the University of Pennsylvania School of Medicine have discovered that an enzyme produced by lung-infecting bacteria further shuts down a protein that is defective in cystic fibrosis patients.

19 Apr 2007

Bacteria barge inside guard cells and initiate a powerful immune response

Immune cells that are the body's front-line defense don't necessarily rest quietly until invading bacteria lock onto receptors on their outside skins and rouse them to action, as previously thought.

18 Apr 2007

Nanoparticles could damage DNA and lead to cancer

Tissue studies indicate that nanoparticles, engineered materials about a billionth of a meter in size, could damage DNA and lead to cancer, according to research presented at the 2007 Annual Meeting of the American Association for Cancer Research.

18 Apr 2007

Better understanding of membrane fusion

Cells constantly swap cargo bound in vesicles, miniscule membrane-enclosed packages of proteins and other chemicals. Before the swap can take place, the vesicle membrane must fuse with another membrane, creating channels packages can pass through.

18 Apr 2007

Mapping rhesus macaque genome helps illuminate what makes us human

Researchers have sequenced the genome of the relatively ancient rhesus macaque ( Macaca mulatta ), providing perspective into how humans are genetically different from our primate relatives.

15 Apr 2007

New device to test for proteins that play important role in human health and disease

A new technology developed at the University of Toronto is revealing biochemical processes responsible for diseases such as cystic fibrosis and could one day pave the way for pharmaceutical applications.

15 Apr 2007

Macaque genome analysis will improve scientists' ability to identify human genes involved in diseases

Cornell experts in computational biology and bioinformatics have made key contributions to the analysis of the genome of the rhesus macaque, better known as the rhesus monkey.

15 Apr 2007

Bacteria can barge inside immune cells

Immune cells that are the body's front-line defense don't necessarily rest quietly until invading bacteria lock onto receptors on their outside skins and rouse them to action, as previously thought. In a new paper, University of Michigan scientists describe their findings that bacteria can barge inside these guard cells and independently initiate a powerful immune response.

14 Apr 2007