Mesenchymal Stem Cells News and Research

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New recombinant antibody can recognize MSCs in umbilical cord blood

A new recombinant antibody can detect and isolate mesenchymal stem cells (MSCs), a nonembryonic source of stem cells with promising applications in tissue engineering, blood stem cell transplantation, and treatments for immune-mediated disorders.

4 Sep 2013

WPI researchers receive NIH grant to develop cell therapies for healing cardiac muscle

The National Institutes of Health (NIH) has awarded a five-year, $1.94 million grant to a biomedical research team at Worcester Polytechnic Institute (WPI) working at the forefront of cell therapies for healing cardiac muscle damaged by heart attack or chronic disease.

29 Aug 2013

Intracerebral injection of BSC may reduce post-stroke cognitive dysfunction

27 Aug 2013

BSCs may offer new approach for reducing post-stroke cognitive dysfunction

Cognitive deficits following ischemic stroke are common and debilitating, even in the relatively few patients who are treated expeditiously so that clots are removed or dissolved rapidly and cerebral blood flow restored. A new study in Restorative Neurology and Neuroscience demonstrates that intracerebral injection of bone-marrow-derived mesenchymal stem cells reduces cognitive deficits produced by temporary occlusion of cerebral blood vessels in a rat model of stroke, suggesting that BSCs may offer a new approach for reducing post-stroke cognitive dysfunction.

26 Aug 2013

Studies reveal potential of HB-EGF in protecting intestines from diverse types of injury

It's not often that one treatment offers therapeutic potential for multiple conditions. However, after more than two decades of research, Gail Besner, MD, principal investigator for the Center for Perinatal Research and pediatric surgeon for the Department of Pediatric Surgery at Nationwide Children's Hospital, and her team have found that this may just be the case with HB-EGF, or heparin-binding EGF-like growth factor.

21 Aug 2013

Repair of sciatic nerve defects using tissue engineered nerves

Peripheral nerve defects are very common in clinical surgery. For repair of short-segment nerve defects, freeing nerve, nerve diversions or joint flexion can be used to directly connect the two stumps of nerves by using microsurgical techniques; while for long-segment nerve defects, we require a bridging material to bridge defected nerves.

16 Aug 2013

Study: Stem cells in mouth tissue can relieve inflammatory disease

Stem cells found in mouth tissue can not only become other types of cells but can also relieve inflammatory disease, according to a new Ostrow School of Dentistry of USC study in the Journal of Dental Research.

5 Aug 2013

Alcohol Research Program at Loyola University receives four NIH grants totaling $3M dollars

The Alcohol Research Program at Loyola University Chicago Stritch School of Medicine recently received four research grants, totaling more than $3 million, from the National Institutes of Health.

26 Jul 2013

Melatonin pre-treatment greatly increases cell survival, say researchers

When melatonin, a hormone secreted by the pineal gland, was used as a pre-treatment for mesenchymal stem cells prior to their transplantation into the brains of laboratory animals to repair damage from stroke, researchers in China found that the stem cells survived longer after transplantation. Previous studies had shown that 80 percent of transplanted MSCs died within 72 hours of transplantation.

23 Jul 2013

Magnets could be used for directing stem cells, may help treat heart and vascular diseases

Magnets could be a tool for directing stem cells' healing powers to treat conditions such as heart disease or vascular disease.

17 Jul 2013

New noninvasive technique for tracking stem cells after transplantation

A new, noninvasive technique for tracking stem cells after transplantation - developed by a cross-disciplinary team of radiologists, chemists, statisticians and materials scientists at the Stanford University School of Medicine - could help surgeons determine whether a procedure to repair injured or worn-out knees is successful.

12 Jul 2013

Scientists track down origins of fibrosis-promoting cells that scar and destroy organs

Scientists have tracked down and quantified the diverse origins of cells that drive fibrosis, the incurable, runaway wound-healing that scars and ultimately destroys organs such as the lungs, liver and kidneys.

2 Jul 2013

Researchers develop new drug delivery systems to treat cancer by blocking signaling receptor

A cardiac hormone signaling receptor abundantly expressed both in inflamed tissues and cancers appears to recruit stem cells that form the blood vessels needed to feed tumor growth, reports a new study by scientists at the University of South Florida Nanomedicine Research Center.

30 Jun 2013

Bioapplications of nanoparticles: an interview with Dr Catherine Berry, University of Glasgow

These particles are all classed as inorganic particles, which can all be utilised in biomedical applications. They differ in terms of their inherent material and size dependent physiochemical properties, for example, their optical and magnetic properties.

18 Jun 2013

Study offers hope for development of novel treatments for stroke, neurological diseases

A specific MicroRNA, a short set of RNA (ribonuclease) sequences, naturally packaged into minute (50 nanometers) lipid containers called exosomes, are released by stem cells after a stroke and contribute to better neurological recovery according to a new animal study by Henry Ford Hospital researchers.

14 Jun 2013

Bioengineers find innovative ways to grow new cartilage from patient's own stem cells

Cartilage injuries are difficult to repair. Current surgical options generally involve taking a piece from another part of the injured joint and patching over the damaged area, but this approach involves damaging healthy cartilage, and a person's cartilage may still deteriorate with age.

5 Jun 2013

Transplantation of human stem cells improves muscle function in rats used to model ALS

Transplantation of human stem cells in an experiment conducted at the University of Wisconsin-Madison improved survival and muscle function in rats used to model ALS, a nerve disease that destroys nerve control of muscles, causing death by respiratory failure.

29 May 2013

Researchers issue statement regarding use of unproven stem cell therapies

An international group of leading stem cell researchers has issued a statement that specifies concerns about the development and use of unproven stem cell therapies.

4 May 2013

Study confirms that mesenchymal stem cells may help treat cancer

Injection of human stem cells into mice with tumors slowed down tumor growth, finds research published in BioMed Central's open access journal Stem Cell Research & Therapy.

29 Apr 2013

Researchers use common virus to modify adult stem cells

Using the same strategy that a common virus employs to evade the human immune system, researchers at Wake Forest Baptist Medical Center's Institute for Regenerative Medicine have modified adult stem cells to increase their survival - with the goal of giving the cells time to exert their natural healing abilities.

2 Apr 2013