Messenger RNA (mRNA) News and Research

RSS

Findings may lead to better ways for preventing gum disease, diabetes and Crohn's disease

Bacteria inside your mouth drastically change how they act when you're diseased, according to research using supercomputers at the Texas Advanced Computing Center.

13 Aug 2014

Oncothyreon acquires Alpine Biosciences to enable targeted delivery of multiple therapeutic agents

Oncothyreon Inc., a biotechnology company specializing in the development of innovative therapeutic products for the treatment of cancer, today announced that it has acquired Alpine Biosciences, Inc., of Seattle, Washington, a privately held biotechnology company developing protocells, a nanoparticle platform technology designed to enable the targeted delivery of multiple therapeutic agents, including nucleic acids, proteins, peptides and small molecules.

12 Aug 2014

Isoform: New protein offers novel therapeutic approach for patients with DMD

Scientists have discovered a new form of dystrophin, a protein critical to normal muscle function, and identified the genetic mechanism responsible for its production.

11 Aug 2014

Celsion announces financial results for second quarter ended 2014

Celsion Corporation, an oncology drug development company, today announced financial results for the second quarter ended June 30, 2014.

7 Aug 2014

UCSF researchers identify novel molecular features within the developing human brain

UC San Francisco researchers have identified cells' unique features within the developing human brain, using the latest technologies for analyzing gene activity in individual cells, and have demonstrated that large-scale cell surveys can be done much more efficiently and cheaply than was previously thought possible.

7 Aug 2014

CRIPTO1 role in TKI resistance elucidated

Overexpression of CRIPTO1 may explain intrinsic tyrosine kinase inhibitor resistance in around 10% of patients with non-small-cell lung cancer and endothelial growth factor receptor mutations, research indicates.

23 Jul 2014

Vanderbilt-led research team identifies protein "signatures" that drive colorectal cancer

A Vanderbilt University-led research team has identified protein "signatures" of genetic mutations that drive colorectal cancer, the nation's second leading cause of cancer deaths after lung cancer.

23 Jul 2014

New molecular analysis tool to detect targets for immunotherapy in early-stage breast cancers

Yale Cancer Center researchers used a new molecular analysis tool to accurately detect the level of an important target for immunotherapy in early-stage breast cancers.

21 Jul 2014

TAZ represents a novel therapeutic target in NSCLC

Patients with non-small-cell lung cancer who express high levels of transcriptional coactivator with PDZ-binding motif may be a clinically distinct subgroup with an unfavourable prognosis, researchers report.

16 Jul 2014

Researchers reveal molecular interplay between Roquin and RNA

The Roquin protein, discovered in 2005, controls T-cell activation and differentiation by regulating the expression of certain mRNAs. In doing so, it helps to guarantee immunological tolerance and prevents immune responses against the body's own structures that can lead to autoimmune disease.

16 Jul 2014

New tools for detecting and monitoring TB in captive elephants

Mycobacterium tuberculosis, the organism that causes tuberculosis in humans, also afflicts Asian (and occasionally other) elephants. Diagnosing and treating elephants with TB is a challenge, however, as little is known about how their immune systems respond to the infection.

16 Jul 2014

Inflammatory shift in long-standing bipolar disorder

Patients with chronic bipolar disorder, but not those with schizophrenia, have a shift towards an M1 rather than an M2 macrophage response, research suggests.

15 Jul 2014

Advanced Cell Diagnostics’ in situ hybridization technology reaches two major milestones

Advanced Cell Diagnostics Inc. (ACD), a leader in the field of molecular pathology and developer of cell and tissue-based analysis tools, has announced that its RNAscope® RNA in situ hybridization technology has reached two major milestones. In just three years, over 100 peer-reviewed papers featuring the technology have been published, and with the significant increase in use of RNAscope, ACD has now built a library of over 4000 target probes for numerous species. Probes are designed to order in under two weeks, and in just six months the library has grown by over 1500, reflecting the wide interest in ACD’s breakthrough technology.

From Advanced Cell Diagnostics 15 Jul 2014

Marginal division of striatum plays similar function in learning and memory to hippocampus

In addition to the hippocampus, the marginal division of the striatum is also involved in learning and memory.

15 Jul 2014

New genetic programs for taking blank-slate stem cells and turning them into human blood

The ability to reliably and safely make in the laboratory all of the different types of cells in human blood is one key step closer to reality.

14 Jul 2014

Study to understand molecular interplay between Roquin and RNA to treat autoimmune diseases

Scientists at the Helmholtz Zentrum München, the Ludwig-Maximilians University of Munich (LMU) and the Technische Universität München (TUM) have moved an important step closer to understanding molecular mechanisms of autoimmune diseases.

14 Jul 2014

Scientists develop RNA that binds cGMP

The transmission of signals within cells is dependent on cyclic guanosine monophosphate (cGMP) as an important secondary messenger. German scientists have now developed an RNA that binds cGMP. As reported in the journal Angewandte Chemie, it is possible to suppress the cGMP signal cascade in genetically modified cells that produce this RNA.

10 Jul 2014

Rockefeller scientists identify protein that makes breast cancer cells more likely to metastasize

Using an innovative tool that captures heretofore hidden ways that cells are regulated, scientists at Rockefeller University have identified a protein that makes breast cancer cells more likely to metastasize.

10 Jul 2014

Webinar outlines novel findings from RNA-Seq project performed by OGT

Oxford Gene Technology (OGT), The Molecular Genetics Company, has made the latest in its series of educational webinars available to watch online at www.ogt.com/webinars. In the webinar entitled “Developing new insights into gene expression using RNA-Seq”, Dr Christopher Jones, Research Fellow at the Brighton and Sussex Medical School (BSMS), UK, presents novel findings from a recent RNA-Seq project performed by OGT.

From Oxford Gene Technology 2 Jul 2014

Celsion acquires all assets of EGEN

Celsion Corporation, an oncology drug development company, today announced the completion of the acquisition by Celsion of substantially all of the assets of EGEN, Inc., a privately-held biopharmaceutical company focused on the development of nucleic acid-based therapeutics for the treatment of cancer and other difficult to treat diseases.

21 Jun 2014

Messenger RNA (mRNA) News and Research

Findings may lead to better ways for preventing gum disease, diabetes and Crohn's disease

Oncothyreon acquires Alpine Biosciences to enable targeted delivery of multiple therapeutic agents

Isoform: New protein offers novel therapeutic approach for patients with DMD

Celsion announces financial results for second quarter ended 2014

UCSF researchers identify novel molecular features within the developing human brain

CRIPTO1 role in TKI resistance elucidated

Vanderbilt-led research team identifies protein "signatures" that drive colorectal cancer

New molecular analysis tool to detect targets for immunotherapy in early-stage breast cancers

TAZ represents a novel therapeutic target in NSCLC

Researchers reveal molecular interplay between Roquin and RNA

New tools for detecting and monitoring TB in captive elephants

Inflammatory shift in long-standing bipolar disorder

Advanced Cell Diagnostics’ in situ hybridization technology reaches two major milestones

Marginal division of striatum plays similar function in learning and memory to hippocampus

New genetic programs for taking blank-slate stem cells and turning them into human blood

Study to understand molecular interplay between Roquin and RNA to treat autoimmune diseases

Scientists develop RNA that binds cGMP

Rockefeller scientists identify protein that makes breast cancer cells more likely to metastasize

Webinar outlines novel findings from RNA-Seq project performed by OGT

Celsion acquires all assets of EGEN

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

Latest Life Science News