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Study suggests new approach to make radiation therapy more effective for glioblastoma patients

Many modern cancer drugs target a specific genetic mutation that is driving a particular cancer's runaway growth and division -- such as the HER-2 protein in some breast cancers or EGFR in certain lung cancers.

30 Jul 2020

Antioxidant-rich foods may increase risk for bowel cancers, study finds

It is a fact that has long baffled doctors: Cancer in the small intestine is quite rare, whereas colorectal cancer, a neighboring though much smaller organ, is one of the leading causes of cancer death for men and women. What is it about the colon that seems to "attract" cancer?

29 Jul 2020

Low plasma vitamin D level appears to be an independent risk factor for COVID-19 infection

Vitamin D is recognized as an important co-factor in several physiological processes linked with bone and calcium metabolism, and also in diverse non-skeletal outcomes, including autoimmune diseases, cardiovascular diseases, type 2 diabetes, obesity and cognitive decline, and infections.

27 Jul 2020

Study: L-Grb2 has therapeutic efficacy in preclinical models of ovarian and uterine cancer

The cover for issue 29 of Oncotarget features, "In vivo effects of treatment with L-Grb2 in combination with anti-angiogenic therapy in an ovarian tumor model," by Lara, et al. which reported that adaptor proteins such as growth factor receptor-bound protein-2 play important roles in cancer cell signaling.

23 Jul 2020

Research suggests a possible new approach to treating neurodegenerative diseases

Researchers at Vanderbilt University Medical Center have shown for the first time that when one optic nerve in the eye is damaged, as in glaucoma, the opposite optic nerve comes to the rescue by sharing its metabolic energy.

21 Jul 2020

An abundance of biomolecules linked to COVID-19 status and severity

Tapping into the potential of the multi-omic method to uncover functional connections between various classes of biomolecules, researchers from notable institutions in the United States have discovered sets of co-varying molecules that shed light on coronavirus disease (COVID-19) pathophysiology and provide treatment opportunities.

20 Jul 2020

Study identifies toxicological risks of environmental pollutants in finless porpoises

A recent study just published in Environmental Science & Technology identified the toxicological risks of environmental pollutants to finless porpoises (Neophocaena asiaeorientalis).

20 Jul 2020

George Mason researcher explores if COVID-19 could be diagnosed via sweat metabolites

Emanuela Marasco, Assistant Professor, Center for Secure Information Systems, is working to determine whether COVID-19 could be diagnosed via sweat metabolites.

17 Jul 2020

Common antioxidant enzyme catalase as COVID-19 treatment

A new paper by researchers from the USA and China and published on the preprint server bioRxiv in July 2020 discusses a new drug based on the catalase enzyme, which could play a vital part in reducing the inflammation associated with progressive and severe COVID-19 disease.

17 Jul 2020

Research will help improve diagnosis of disease in newborn babies from urine samples

New research will help health-care practitioners to more accurately diagnose disease and illness in newborn babies from urine samples, according to a study by researchers at the University of Alberta and the Universidad Autónoma de Zacatecas.

16 Jul 2020

Bed bugs alter microbial community composition of infested homes

Homes infested by bed bugs appear to have different bacterial communities - often referred to as microbiomes - than homes without bed bugs, according to a first-of-its-kind study from North Carolina State University.

15 Jul 2020

SARS-CoV-2 a dagger to the aging heart

Researchers in Europe have shown that genes involved in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are expressed to a higher degree in older heart muscle cells (cardiomyocytes) than they are in younger cardiomyocytes.

9 Jul 2020

Aspirin and flavonoids in fruits and vegetables could help prevent colorectal cancer

A diet rich in fruits and vegetables and a daily dose of aspirin have one thing in common-;both can help prevent colorectal cancer. Yet scientists have struggled for decades to find the source of their ability to inhibit cancer cell growth.

7 Jul 2020

Study: Oats and rye brans reduce weight gain, hepatic inflammation

In a newly published experimental study, the consumption of dietary fibre from oat and rye brans supported the growth of beneficial gut microbiota, which in turn ameliorated cholesterol metabolism, enhanced gut barrier function and reduced hepatic inflammation.

2 Jul 2020

Novel microbiome-based diagnostic tool can identify liver fibrosis, cirrhosis

Chronic liver disease represents a major global public health problem affecting an estimated 844 million people, according to the World Health Organization. It is among the top causes of mortality in Australia, the UK and the United States.

2 Jul 2020

Blood cell damage in COVID-19 may compromise oxygen transport

Researchers in the U.S. have shown that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may alter key protein structures on red blood cells and compromise the transport and delivery of oxygen in patients with coronavirus disease 2019 (COVID-19).

1 Jul 2020

Stool microbial and metabolite signatures predict cirrhosis

Nonalcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease worldwide, affecting an estimated one-quarter of the global population. It is a progressive condition that, in worst cases, can lead to cirrhosis, liver cancer, liver failure and death.

30 Jun 2020

High fiber diet may improve the quality of life for patients with ulcerative colitis

Eating diets low in fat and high in fiber may improve the quality of life of patients with ulcerative colitis (UC) -; even those in remission.

30 Jun 2020

New steroid compounds from deep-water starfish show anticancer activity

Russian scientists from Far Eastern Federal University, G. B. Elyakov Pacific Institute of Bioorganic Chemistry, and A.V. Zhirmunsky National Scientific Center for Marine Biology have discovered four new steroid substances which target cells of human breast cancer, and colorectal carcinoma.

26 Jun 2020

Irritable bowel disease heightens the risk of dementia

Scientists have long explored the link between the gut and the brain. Now, a new study shows that older adults with chronic inflammation of the digestive tract may develop dementia more than seven years earlier than those who do not have the condition.

26 Jun 2020

Metabolites News and Research

Study suggests new approach to make radiation therapy more effective for glioblastoma patients

Antioxidant-rich foods may increase risk for bowel cancers, study finds

Low plasma vitamin D level appears to be an independent risk factor for COVID-19 infection

Study: L-Grb2 has therapeutic efficacy in preclinical models of ovarian and uterine cancer

Research suggests a possible new approach to treating neurodegenerative diseases

An abundance of biomolecules linked to COVID-19 status and severity

Study identifies toxicological risks of environmental pollutants in finless porpoises

George Mason researcher explores if COVID-19 could be diagnosed via sweat metabolites

Common antioxidant enzyme catalase as COVID-19 treatment

Research will help improve diagnosis of disease in newborn babies from urine samples

Bed bugs alter microbial community composition of infested homes

SARS-CoV-2 a dagger to the aging heart

Aspirin and flavonoids in fruits and vegetables could help prevent colorectal cancer

Study: Oats and rye brans reduce weight gain, hepatic inflammation

Novel microbiome-based diagnostic tool can identify liver fibrosis, cirrhosis

Blood cell damage in COVID-19 may compromise oxygen transport

Stool microbial and metabolite signatures predict cirrhosis

High fiber diet may improve the quality of life for patients with ulcerative colitis

New steroid compounds from deep-water starfish show anticancer activity

Irritable bowel disease heightens the risk of dementia

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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