Metagenomics News and Research

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Computational algorithms provide insight into how gut microbiota respond to infection over time

Being sick due to an infection can make us feel lousy. But what must the ecosystem of bacteria, or microbiota, colonizing our guts be going through when hit with infection? A study from Brigham and Women's Hospital (BWH) has utilized unique computational models to show how infection can affect bacteria that naturally live in our intestines.

14 Jul 2014

Research on intestinal microbiota overturns vision of human gut ecosystem

An international research team within the MetaHIT consortium coordinated by INRA and involving teams from CEA, CNRS and Université d'Evry, has developed a new method to analyse the global genome, or the metagenome of the intestinal microbiota.

7 Jul 2014

Synthetic, Enterome partner to study effects of beta-lactam antibiotics on gastrointestinal microflora

Synthetic Biologics, Inc., a developer of novel anti-infective biologic and drug candidates targeting specific pathogens that cause serious infections and diseases, and Enterome Bioscience SA, a pioneer in the development of innovative disease management solutions based on a deep understanding of the gut microbiome, today announced that they have entered into an agreement to conduct metagenomic research on the effects of beta-lactam antibiotics on the gastrointestinal microflora (microbiome) of human patients.

10 Jun 2014

Scientists use novel metagenomic approaches to characterize microbial communities that reside in human gut

The gut microbiota contains a vast number of microorganisms from all three domains of life, including bacteria, archaea and fungi, as well as viruses. These interact in a complex way to contribute towards both health and the development of disease - interactions that are only now being elucidated thanks to the application of advanced DNA sequencing technology in this field.

10 Mar 2014

Friendly microbes in the guts of healthy children have numerous antibiotic resistance genes

Friendly microbes in the intestinal tracts (guts) of healthy American children have numerous antibiotic resistance genes, according to results of a pilot study by scientists at Washington University School of Medicine in St. Louis.

14 Nov 2013

MO BIO Laboratories introduces UltraClean-htp 96 Well Swab DNA Kit

MO BIO Laboratories, Inc., the leader in microbial, stool, plant, and soil nucleic acid purification, announces the launch of the UltraClean-htp 96 Well Swab DNA Kit. The kit is designed for rapid mechanical lysis of microbial cells from low biomass and low inhibitor containing swabs, paper or filter paper for direct application to PCR for metagenomic analysis.

2 Oct 2013

NIH awards 10 new grants to support genomics research in Africa

The National Institutes of Health has awarded 10 new grants totaling up to $17 million over the next four years to support genomics research in Africa, as part of the Human Heredity and Health in Africa (H3Africa) program

2 Oct 2013

libragen contributes to success of PolyModE

libragen, a contract research organization dedicated to biocatalysis and metagenomics, has been a major contributor to the success of PolyModE (Polysaccharide Modifying Enzymes), a large collaborative research project funded by the European Community. The project, which began in 2009 and ended in April this year, looked at developing novel polysaccharide modifying enzymes for the optimized use of hydrocolloids as, for example, food additives or novel therapeutic agents in the food sciences and medical industries. Researchers focused on six industry-targeted hydrocolloids (alginates, carrageenans, chitosans, glycosaminoglycans, pectins, and xanthan gums) where traditional chemistry fails to achieve a certain desired modification.

2 Oct 2013

Illumina announces availability of its newest reagent kits for MiSeq benchtop sequencer

Illumina, Inc. today announced the availability of its newest reagent kits for the MiSeq, the industry's most accurate and easiest-to-use benchtop sequencer. The improved chemistry doubles sequencing output to 15 gigabases (Gb) by increasing the number of sequencing reads (up to 25 million reads) and overall read length (up to 2x300 base pairs). These innovations enable researchers to perform new applications including exome sequencing on the MiSeq.

From Illumina, Inc. 19 Aug 2013

Children born by Caesarean section more vulnerable to allergies

Children who came into the world by Caesarean section are more often affected by allergies than those born in the natural way. The reason for this may be that they have a less diverse gut microbiota, according to a study by universities in Sweden and Scotland.

9 Aug 2013

Roche releases new software for accurate sequencing of long 16S ribosomal RNA amplicons

Roche announced today the global launch of a new software update that significantly extends the range of amplicon lengths available for targeted next-generation sequencing studies on the 454 GS FLX+ System.

7 Aug 2013

Metagenomics technique used to recover TB genomes from 215-year old mummy

Researchers at the University of Warwick have recovered tuberculosis (TB) genomes from the lung tissue of a 215-year old mummy using a technique known as metagenomics.

20 Jul 2013

Patients with type 2 diabetes have altered gut microbiota

Intestinal bacteria may have a greater influence on us than was previously thought. In a study published in the prestigious journal Nature on 29 May, researchers at the Sahlgrenska Academy, University of Gothenburg, Sweden and Chalmers University of Technology, Sweden, show that patients with type 2 diabetes have an altered gut microbiota.

3 Jun 2013

Researchers use metagenomics to identify the cause of outbreaks of bacterial infection

Researchers have been able to reconstruct the genome sequence of an outbreak strain of Shiga-toxigenic Escherichia coli (STEC), which caused over 50 deaths in Germany, using an approach known as metagenomics which bypasses the need for growing bacteria in the lab.

12 Apr 2013

Researchers use metagenomics to reconstruct genome sequence of Shiga-toxigenic Escherichia coli

Researchers have been able to reconstruct the genome sequence of an outbreak strain of Shiga-toxigenic Escherichia coli using metagenomics (the direct sequencing of DNA extracted from microbiologically complex samples), according to a study in the April 10 issue of JAMA, a Genomics theme issue.

10 Apr 2013

Scientists take important step toward designing a uniform protocol for microbiome research

Earth Day may be more than a month away, but another, more personal, ecosystem has been shown to also be worth protecting-within our bodies are communities of microbes that affect the behavior of human cells hosting them.

1 Mar 2013

Altered gut microbiota associated with symptomatic atherosclerosis and stroke

Researchers at the University of Gothenburg, Sweden, and the Chalmers University of Technology, Sweden, demonstrate that an altered gut microbiota in humans is associated with symptomatic atherosclerosis and stroke.

15 Dec 2012

Study catalogs genetic variation of microbes that live in the gut

Our bodies contain far more microbial genes than human genes. And a new study suggests that just as human DNA varies from person to person, so too does the massive collection of microbial DNA in the intestine.

6 Dec 2012

METACARDIS project to develop and implement personalized treatments for patients with CMDs

Thanks to the support of the European Commission, fourteen partners in six European countries will work together over a five-year period to translate the results obtained with novel CMD diagnosis and treatment methods and pave the way for personalised medicine in CMDs. Researchers and clinicians from the Institute of Cardiometabolism and Nutrition (ICAN) will also be involved in the METACARDIS project.

5 Dec 2012

Chronic suppurative lung disease: an interview with Dr Robyn Marsh

Chronic suppurative lung disease, or CSLD, is used to describe a range of lung diseases characterised by a chronic wet cough and progressive lung damage. We are interested in the non-cystic fibrosis forms of the disease with a focus on bronchiectasis – the severe form of CSLD.

26 Nov 2012

Metagenomics News and Research

Computational algorithms provide insight into how gut microbiota respond to infection over time

Research on intestinal microbiota overturns vision of human gut ecosystem

Synthetic, Enterome partner to study effects of beta-lactam antibiotics on gastrointestinal microflora

Scientists use novel metagenomic approaches to characterize microbial communities that reside in human gut

Friendly microbes in the guts of healthy children have numerous antibiotic resistance genes

MO BIO Laboratories introduces UltraClean-htp 96 Well Swab DNA Kit

NIH awards 10 new grants to support genomics research in Africa

libragen contributes to success of PolyModE

Illumina announces availability of its newest reagent kits for MiSeq benchtop sequencer

Children born by Caesarean section more vulnerable to allergies

Roche releases new software for accurate sequencing of long 16S ribosomal RNA amplicons

Metagenomics technique used to recover TB genomes from 215-year old mummy

Patients with type 2 diabetes have altered gut microbiota

Researchers use metagenomics to identify the cause of outbreaks of bacterial infection

Researchers use metagenomics to reconstruct genome sequence of Shiga-toxigenic Escherichia coli

Scientists take important step toward designing a uniform protocol for microbiome research

Altered gut microbiota associated with symptomatic atherosclerosis and stroke

Study catalogs genetic variation of microbes that live in the gut

METACARDIS project to develop and implement personalized treatments for patients with CMDs

Chronic suppurative lung disease: an interview with Dr Robyn Marsh

Omics eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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