Metastasis News and Research

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Metastasis is the spread of cancer from one part of the body to another. A tumor formed by cells that have spread is called a “metastatic tumor” or a “metastasis.” The metastatic tumor contains cells that are like those in the original (primary) tumor. The plural form of metastasis is metastases

OncoGenex, Teva's custirsen preclinical data in CRPC presented at AACR meeting

Teva Pharmaceutical Industries Ltd. and OncoGenex Pharmaceuticals, Inc. announced today that new preclinical data of their investigational compound custirsen in castrate resistant prostate cancer were presented this week at the 102nd Annual Meeting of the AACR.

7 Apr 2011

USPTO issues notice of allowance to Mirna's mir34a patent application

Mirna Therapeutics, Inc. announced today that the United States Patent and Trademark Office has allowed patent claims related to the therapeutic application of the potent tumor suppressor microRNA, mir34a.

7 Apr 2011

Circadian's VGX-100 neutralises VEGF-C and inhibits tumour growth in mouse models of human cancers

Circadian Technologies Limited today released data at the American Association for Cancer Research (AACR) annual conference in Orlando, Florida (U.S.A.) demonstrating that its lead anti-cancer therapeutic, VGX-100, significantly inhibits tumour growth and spread in a variety of different mouse models of human cancer.

7 Apr 2011

VBL's VB-111 preclinical data against metastatic cancer presented at AACR meeting

VBL Therapeutics, a clinical-stage biotechnology company committed to the development of novel treatments for immune-inflammatory diseases and cancer, today announced preclinical data demonstrating VB-111's potential utility as a targeted cancer treatment.

7 Apr 2011

ImClone Systems initiates IMC-3C5 Phase 1 trial in patients with advanced solid tumours

Circadian Technologies announced today that its licensee ImClone Systems, a wholly-owned subsidiary of Eli Lilly and Company, has advised that it has commenced the first Phase 1 clinical trial of its fully-human monoclonal antibody IMC-3C5.

6 Apr 2011

Under stressful conditions, presence of high levels of HER2 protein causes a decrease in autophagy

Research from The Cancer Institute of New Jersey (CINJ) on biological pathways that govern progression and treatment responsiveness of HER2 positive breast cancer is being presented at the 102nd Annual Meeting of the American Association for Cancer Research (AACR) being held in Orlando this week. CINJ is a Center of Excellence of UMDNJ-Robert Wood Johnson Medical School.

6 Apr 2011

Pervasis' PVS-30200 study data in prostate cancer presented at AACR meeting

Pervasis Therapeutics, Inc. today announced preclinical data showing positive effects of PVS-30200, the company's investigational cell therapy for the treatment of solid tumors, on controlling tumor growth and inhibiting metastases in an animal model of prostate cancer.

6 Apr 2011

Tumor cryoablation coupled with immunotherapy amplifies tumor immunity

Scientists at the Barbara Ann Karmanos Cancer Institute in Detroit today presented data at the American Association for Cancer Research's 102nd Annual Meeting 2011 showing that when tumor cryoablation – or the freezing of tumor tissue while preserving tumor-associated antigens – is coupled with immune system modulation, the procedures have the potential to initiate or amplify tumor immunity.

5 Apr 2011

Preliminary discovery may help individualize prostate cancer screening in the future

Prostate cancer is the second leading cause of cancer-related death among American men. Yet population-wide screening programs have not reduced the number of deaths from the disease. By focusing screening programs on the men who are at greatest risk for aggressive disease or diagnosis at a young age, researchers think they could improve mortality rates and personalize the screening approach.

5 Apr 2011

Human immune system can help predict recurrence, overall breast cancer survival

A study published in Cancer Discovery, the newest journal of the American Association for Cancer Research, debuting here at the AACR 102nd Annual Meeting 2011, held April 2-6, showed how evaluating the immune response in the tumor microenvironment may help researchers better target therapy in breast cancer.

4 Apr 2011

Researchers discover immune system can help predict breast cancer survival

A team of researchers at the University of California, San Francisco has discovered a new way to predict breast cancer survival based on an "immune profile" - the relative levels of three types of immune cells within a tumor. Knowing a patient's profile may one day help guide treatment.

4 Apr 2011

Study: MicroRNA can predict risk of BM in lung cancer patients

Conducting genetic profiles using microRNA can help doctors predict which lung cancer patients are likely to also develop brain metastasis, according to a study published today by Scottsdale Healthcare and the Translational Genomics Research Institute.

1 Apr 2011

New research: 'Good cholesterol' can act as special delivery vehicle for cancer destruction

High-density lipoprotein's hauls excess cholesterol to the liver for disposal, but new research suggests "good cholesterol" can also act as a special delivery vehicle of destruction for cancer.

1 Apr 2011

Analysis of non-tumor tissue may be an effective option for diagnosis of prostate cancer

Researchers have found that it may not be necessary to look for tumors directly in patients with prostate cancer - analyzing non-tumor tissue may be an effective option, according to study results published in Cancer Research, a journal of the American Association for Cancer Research.

1 Apr 2011

TNM 7 system can predict lung cancer recurrence after surgery

The new TNM 7 lung cancer staging system seems to be a better predictor of local or regional recurrence of lung cancer following surgery, according to a study published in the April issue of the Journal of Thoracic Oncology.

1 Apr 2011

BMY receives FDA approval for YERVOY to treat metastatic melanoma

Bristol-Myers Squibb Company today announced that the U.S. Food and Drug Administration approved YERVOY 3 mg/kg for the treatment of patients with unresectable or metastatic melanoma.

28 Mar 2011

New study provides insights into epiboly mechanisms linked with wound healing, cancer

Avian embryos could join the list of model organisms used to study a specific type of cell migration called epiboly, thanks to the results of a study published this month in the journal Developmental Dynamics.

24 Mar 2011

New study: Prostate and breast cancer usually recur in bone

Like bad neighbors who decide to go wreck another community, prostate and breast cancer usually recur in the bone, according to a new University of Michigan study.

24 Mar 2011

Study finds novel physical mechanism behind cancer migration

Ninety percent of cancer deaths resulted from metastasis, the spread of cancer to different areas in the body, yet scientific exploration of the possible mechanical factors that promote metastasis has been limited.

23 Mar 2011

$Cancer patients with spinal fractures can benefit from Kyphon Balloon Kyphoplasty$

Cancer patients with spinal fractures can benefit from Kyphon Balloon Kyphoplasty

Medtronic of Canada Ltd. today announced the results of the first randomized, controlled trial comparing Kyphon Balloon Kyphoplasty with non-surgical care in treating spinal fractures in cancer patients.

23 Mar 2011

Metastasis News and Research

Further Reading

OncoGenex, Teva's custirsen preclinical data in CRPC presented at AACR meeting

USPTO issues notice of allowance to Mirna's mir34a patent application

Circadian's VGX-100 neutralises VEGF-C and inhibits tumour growth in mouse models of human cancers

VBL's VB-111 preclinical data against metastatic cancer presented at AACR meeting

ImClone Systems initiates IMC-3C5 Phase 1 trial in patients with advanced solid tumours

Under stressful conditions, presence of high levels of HER2 protein causes a decrease in autophagy

Pervasis' PVS-30200 study data in prostate cancer presented at AACR meeting

Tumor cryoablation coupled with immunotherapy amplifies tumor immunity

Preliminary discovery may help individualize prostate cancer screening in the future

Human immune system can help predict recurrence, overall breast cancer survival

Researchers discover immune system can help predict breast cancer survival

Study: MicroRNA can predict risk of BM in lung cancer patients

New research: 'Good cholesterol' can act as special delivery vehicle for cancer destruction

Analysis of non-tumor tissue may be an effective option for diagnosis of prostate cancer

TNM 7 system can predict lung cancer recurrence after surgery

BMY receives FDA approval for YERVOY to treat metastatic melanoma

New study provides insights into epiboly mechanisms linked with wound healing, cancer

New study: Prostate and breast cancer usually recur in bone

Study finds novel physical mechanism behind cancer migration

Cancer patients with spinal fractures can benefit from Kyphon Balloon Kyphoplasty

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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