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Preclinical data from Synthetic Biologics' SYN-005 for Pertussis treatment presented at ECCMID 2015

Synthetic Biologics, Inc., a developer of pathogen-specific therapies for serious infections and diseases, with a focus on protecting the microbiome, announced that preclinical data from its novel SYN-005 program for the treatment of Pertussis were presented in two posters at ECCMID 2015 (European Congress of Clinical Microbiology and Infectious Diseases), on April 25, 2015, in Copenhagen, Denmark.

27 Apr 2015

Study points to TMPRSS2 gene as culprit for aggressive forms of androgen-fuelled cancers

A new study led by University of Toronto researcher Dr. David Lam has discovered the trigger behind the most severe forms of cancer pain. Released in top journal Pain this month, the study points to TMPRSS2 as the culprit: a gene that is also responsible for some of the most aggressive forms of androgen-fuelled cancers.

24 Apr 2015

Leading scientists warn of 'Antibiotic Armageddon' in Britain and Europe by 2025

A group of leading scientists has warned that Britain and Europe collectively could face more than a million deaths in an impending "Antibiotic Armageddon” unless more is spent on developing new cures, rapid diagnostics and preventative measures to combat the spread of drug resistant diseases.

24 Apr 2015

Debiopharm announces initiation of Debio 1450 phase II study for treatment of ABSSSI

Debiopharm International SA, part of Debiopharm Group, a Swiss-based global biopharmaceutical company, today announced the start of a clinical phase II study to evaluate Debio 1450 for the treatment of Acute Bacterial Skin and Skin Structure Infections (ABSSSI) due to Staphylococci, including all resistant Staphylococcus strains, tested so far.

23 Apr 2015

Metanome changes name to Diversigen

Metanome, Inc., an industry leader in comprehensive microbiome services, today announced the company has changed its name to Diversigen, Inc. The name was changed to reflect Diversigen's positioning as the single commercial source for the myriad of services and expertise customers need to capitalize on the diverse opportunities of the microbiome.

23 Apr 2015

Rising shortages of key antibiotics raise serious concerns about effects on patient care

Shortages of key antibiotics, including gold-standard therapies and drugs used to treat highly resistant infections, are on the rise, according to a new study of shortages from 2001 to 2013 published in Clinical Infectious Diseases and available online. The trends raise serious concerns about the effects on patient care, particularly for infections without effective alternative treatment options.

23 Apr 2015

New UM SOM study uncovers never-before-seen illness transmitted by ticks

Tick-borne diseases are a major public health problem around the world. Ticks carry and transmit a variety of microbes that cause disease. These illnesses, which include Lyme disease, Rocky Mountain spotted fever, and Tularemia, can cause a variety of symptoms, often serious and sometimes deadly.

23 Apr 2015

New patent-pending detection method identifies bacteria contaminating oysters

In a major breakthrough in shellfish management and disease prevention, researchers at the University of New Hampshire have discovered a new method to detect a bacterium that has contaminated New England oyster beds and sickened consumers who ate the contaminated shellfish.

23 Apr 2015

Adseverin protein plays key role in bone loss associated with osteoinflammatory disease

Adseverin, a protein found in the body, has been identified as the key driver behind the bone loss associated with the world's most common inflammatory disease: gum disease, or periodontitis.

23 Apr 2015

French clinicians diagnose first case of rabies since 2003

A team of French clinicians has diagnosed the first case of rabies in that country since 2003. Only 20 cases of human rabies had been diagnosed in France between 1970 and 2003. Moreover, the patient was unaware of having been bitten.

22 Apr 2015

New study sheds light on mechanism that affects AID enzyme

A new study by immunology researchers at the IRCM led by Javier M. Di Noia, PhD, sheds light on a mechanism affecting AID, a crucial enzyme for the immune response. The scientific breakthrough, published in the latest issue of The Journal of Experimental Medicine, could eventually improve the way we treat the common flu, as well as lymphoma and leukemia.

21 Apr 2015

Two existing drugs may reverse damage caused by multiple sclerosis

A pair of topical medicines already alleviating skin conditions each may prove to have another, even more compelling use: instructing stem cells in the brain to reverse damage caused by multiple sclerosis.

21 Apr 2015

Study reveals new target for research into liver disease

In a recent study, Virginia Commonwealth University School of Medicine researchers predicted which cirrhosis patients would suffer inflammations and require hospitalization by analyzing their saliva, revealing a new target for research into a disease that accounts for more than 30,000 deaths in the United States each year.

20 Apr 2015

Maple syrup makes disease-causing bacteria more susceptible to antibiotics, study shows

A concentrated extract of maple syrup makes disease-causing bacteria more susceptible to antibiotics, according to laboratory experiments by researchers at McGill University.

17 Apr 2015

Researchers reveal the precise mechanism used by bacteria to target invading viruses

One of the immune system's most critical challenges is to differentiate between itself and foreign invaders -- and the number of recognized autoimmune diseases, in which the body attacks itself, is on the rise.

17 Apr 2015

Inflammation plays causal role in neurologic changes associated with Lyme disease

About 15% of patients with Lyme disease develop peripheral and central nervous system involvement, often accompanied by debilitating and painful symptoms. New research indicates that inflammation plays a causal role in the array of neurologic changes associated with Lyme disease, according to a study published in The American Journal of Pathology.

17 Apr 2015

James Allison to be honored with 2015 Pezcoller Foundation-AACR International Award for Cancer Research

The 2015 Pezcoller Foundation-American Association for Cancer Research (AACR) International Award for Cancer Research will be presented to James P. Allison, PhD, at the AACR Annual Meeting 2015, to be held in Philadelphia, April 18-22.

17 Apr 2015

Researchers examine how probiotics can help improve health, prevent disease

In recent years, research into the benefits of gut bacteria has exploded. Scientists across the globe are examining how these microbes can help improve health and prevent disease.

16 Apr 2015

Genetically modified Salmonella can help kill cancer cells

A new study has demonstrated that genetically modified Salmonella can be used to kill cancer cells. The study is published in this week's issue of mBio, an American Society for Microbiology online-only, open access journal.

15 Apr 2015

STRIVE study to assess safety, efficacy of rVSV-ZEBOV candidate Ebola vaccine

The Centers for Disease Control and Prevention (CDC), in partnership with the Sierra Leone College of Medicine and Allied Health Sciences and the Sierra Leone Ministry of Health and Sanitation, is now enrolling and vaccinating volunteers for the Sierra Leone Trial to Introduce a Vaccine against Ebola (STRIVE).

15 Apr 2015

Microbiology News and Research

Preclinical data from Synthetic Biologics' SYN-005 for Pertussis treatment presented at ECCMID 2015

Study points to TMPRSS2 gene as culprit for aggressive forms of androgen-fuelled cancers

Leading scientists warn of 'Antibiotic Armageddon' in Britain and Europe by 2025

Debiopharm announces initiation of Debio 1450 phase II study for treatment of ABSSSI

Metanome changes name to Diversigen

Rising shortages of key antibiotics raise serious concerns about effects on patient care

New UM SOM study uncovers never-before-seen illness transmitted by ticks

New patent-pending detection method identifies bacteria contaminating oysters

Adseverin protein plays key role in bone loss associated with osteoinflammatory disease

French clinicians diagnose first case of rabies since 2003

New study sheds light on mechanism that affects AID enzyme

Two existing drugs may reverse damage caused by multiple sclerosis

Study reveals new target for research into liver disease

Maple syrup makes disease-causing bacteria more susceptible to antibiotics, study shows

Researchers reveal the precise mechanism used by bacteria to target invading viruses

Inflammation plays causal role in neurologic changes associated with Lyme disease

James Allison to be honored with 2015 Pezcoller Foundation-AACR International Award for Cancer Research

Researchers examine how probiotics can help improve health, prevent disease

Genetically modified Salmonella can help kill cancer cells

STRIVE study to assess safety, efficacy of rVSV-ZEBOV candidate Ebola vaccine

Microbiology eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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