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Scientists grow complex organoids in the lab

Scientists at the University of Würzburg have successfully produced human tissues from stem cells. They have a complexity similar to that of normal tissue and are far superior to previous structures.

19 Nov 2019

Non-coding enhancer DNA may be key for identifying genetic risk in neurological conditions

One might think that the primary cause of most genetically linked diseases comes from mutations in coding DNA -- alterations in coding regions of the genome that can lead directly to changes in the expression of particular proteins important for a healthy body.

14 Nov 2019

Regulating gut bacteria could calm chemo side effects, reduce cognitive problems

In a new study, scientists observed several simultaneous reactions in mice given a common chemotherapy drug: Their gut bacteria and tissue changed, their blood and brains showed signs of inflammation, and their behaviors suggested they were fatigued and cognitively impaired.

11 Nov 2019

Future drugs aimed at halting cell-inactivation process may help prevent Parkinson's disease

In neurodegenerative conditions like Parkinson's disease, a specific group of neurons start to die one by one, causing movement problems and other symptoms. Scientists have long focused on finding out why these neurons die. Now it turns out, they might not even be dead.

11 Nov 2019

Sartorius publishes third edition of the Live-Cell Analysis Handbook

Sartorius is excited to announce publication of the third edition of our Live-Cell Analysis Handbook, a popular publication for a broad range of scientists who perform cell biology assays as part of their research.

From Sartorius 8 Nov 2019

Liposomes cross blood brain barrier, could get healing drugs to stroke-affected brain

A new study from University of Manchester researchers, published in ACS Neuro, shows a high possibility of treating stroke patients using very small cell sacs called liposomes to bypass the blood brain barrier and carry lifesaving drugs to the brain to prevent damage following a stroke.

7 Nov 2019

Newly discovered immune control switch could protect the brains of premature babies

Researchers have discovered an immune control switch that could protect the brains of premature babies, who often suffer brain injuries when their immune response goes into overdrive.

30 Oct 2019

Researchers make progress toward gene-based strategies to treat inherited neurometabolic diseases

Researchers are making great strides toward developing gene-based strategies to treat a variety of inherited neurometabolic diseases characterized by severe neurological involvement.

29 Oct 2019

Unhealthy gut microbiome reduces brain synaptic pruning, impairs learning

A new study by Weill Cornell Medicine and Cornell University has come up with more explanations of how gut microbes communicate with the brain neurons. The study, published in the journal Nature on October 23, 2019, examined the brains of mouse models and found that when the gut microbiome is significantly reduced, there are changes in gene expression in the brain’s microglial cells.

24 Oct 2019

Molecular processes underlying communication between gut microbes and brain cells revealed

New cellular and molecular processes underlying communication between gut microbes and brain cells have been described for the first time by scientists at Weill Cornell Medicine and Cornell's Ithaca campus.

23 Oct 2019

Link between pregnancy stress, immune activation, and postpartum depression

A new study presented at the Society for Neuroscience meeting on October 19, 2019, at Chicago, shows for the first time how postpartum depression could actually be due to abnormal immune system activation within the brain, which in turn is set off by chronic pregnancy stress. This is the earliest study to show this link in animals.

22 Oct 2019

Link found between unique brain cells and OCD, anxiety

According to the National Institute of Mental Health, 1 in 3 people experience debilitating anxiety-;the kind that prevents someone from going about their normal life.

22 Oct 2019

Study uncovers brain biology behind postpartum depression

Chronic stress during pregnancy triggers an immune response in the brain that has potential to alter brain functions in ways that could contribute to postpartum depression, new research in animals suggests.

22 Oct 2019

Research shows brain's immune system gets activated by stress during pregnancy

21 Oct 2019

Immune cells rewire, repair brain while we sleep, study shows

Science tells us that a lot of good things happen in our brains while we sleep - learning and memories are consolidated and waste is removed, among other things.

21 Oct 2019

A protein could play key role in neurodegenerative diseases, research suggests

Research led by Queen Mary University of London and the University of Seville around one protein's role in regulating brain inflammation could improve our understanding of neurodegenerative diseases.

15 Oct 2019

Discovery could lead to new therapeutic targets for neurodegenerative diseases

Research led by Drs. Miguel Burguillos (University of Seville, Spain) and Miguel Branco (Queen Mary University of London, UK), has revealed new findings about mechanisms regulating brain inflammation which open a new pathway in the field of neuroinflammation.

15 Oct 2019

Simple way to effectively transport medication into the brain identified

For the first time, scientists have identified a simple way that can effectively transport medication into the brain - which could lead to improved treatments for neurological and neurodegenerative diseases.

11 Oct 2019

Suppressing brain immune cells might prevent or delay the onset of dementia

Messy tangles of a protein called tau can be found in the brains of people with Alzheimer's disease and some other neurodegenerative diseases. In Alzheimer's, the tangles coalesce just before tissue damage becomes visible in brain scans and people start to become forgetful and confused.

10 Oct 2019

Rapid progress in brain organoid research prompts ethical debate

A new paper has tried to address the ethical debate surrounding human organoids by evaluating the potential risks of creating “humanized” animals

4 Oct 2019

Microglia News and Research

Scientists grow complex organoids in the lab

Non-coding enhancer DNA may be key for identifying genetic risk in neurological conditions

Regulating gut bacteria could calm chemo side effects, reduce cognitive problems

Future drugs aimed at halting cell-inactivation process may help prevent Parkinson's disease

Sartorius publishes third edition of the Live-Cell Analysis Handbook

Liposomes cross blood brain barrier, could get healing drugs to stroke-affected brain

Newly discovered immune control switch could protect the brains of premature babies

Researchers make progress toward gene-based strategies to treat inherited neurometabolic diseases

Unhealthy gut microbiome reduces brain synaptic pruning, impairs learning

Molecular processes underlying communication between gut microbes and brain cells revealed

Link between pregnancy stress, immune activation, and postpartum depression

Link found between unique brain cells and OCD, anxiety

Study uncovers brain biology behind postpartum depression

Research shows brain's immune system gets activated by stress during pregnancy

Immune cells rewire, repair brain while we sleep, study shows

A protein could play key role in neurodegenerative diseases, research suggests

Discovery could lead to new therapeutic targets for neurodegenerative diseases

Simple way to effectively transport medication into the brain identified

Suppressing brain immune cells might prevent or delay the onset of dementia

Rapid progress in brain organoid research prompts ethical debate

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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