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Study examines if caffeine could prevent harmful effects of PGE1 treatment on breathing

Researchers from the Department of Pediatrics at Case Western Reserve University School of Medicine and University Hospitals Rainbow Babies and Children's Hospital presented results of a study that investigated whether there are any deleterious effects of prostaglandin E1 treatment on breathing and whether these effects would be prevented via pre-treatment with caffeine.

30 Apr 2019

Microglia play vital role in regulating neuroinflammation, research shows

A research team at Massachusetts Eye and Ear has shown that microglia, the primary immune cells of the central nervous system--including the retina of the eye--serve as "gatekeepers," or biosensors and facilitators, of neuroinflammation in a preclinical model of autoimmune uveitis.

23 Apr 2019

Promising diagnostic, prognostic tools for onset and progression of ALS

Amyotrophic lateral sclerosis is a motor neuron disease with rampant progression and that it is typically fatal within 5 years of prognosis.

5 Apr 2019

PET images of microglial activation levels could better predict Alzheimer's disease progression

Researchers have discovered a way to better predict progression of Alzheimer's disease. By imaging microglial activation levels with positron emission tomography, researchers were able to better predict progression of the disease than with beta-amyloid PET imaging, according to a study published in the April issue of the Journal of Nuclear Medicine.

4 Apr 2019

Allergic reactions trigger changes in brain behavior development in unborn males and females

Researchers at the University of Maryland School of Medicine and colleagues at Ohio State University have discovered that allergic reactions trigger changes in brain behavior development in unborn males and females.

29 Mar 2019

Study finds no damaging role for microglia during retinal prion disease in mice

National Institutes of Health scientists studying the progression of inherited and infectious eye diseases that can cause blindness have found that microglia, a type of nervous system cell suspected to cause retinal damage, surprisingly had no damaging role during prion disease in mice.

28 Mar 2019

Allergic reaction during pregnancy may alter sexual-development in offspring's brain

A single allergic reaction during pregnancy prompts sexual-development changes in the brains of offspring that last a lifetime, new research suggests.

22 Mar 2019

Major success achieved by Axol Bioscience may help design new brain models

Axol Bioscience, a partner in the EU-funded MESO-BRAIN project (GA # 713140) has had a new proposal selected for funding by the EU through the FET (Future Emerging Technologies) Launchpad scheme.

From Axol Bioscience Ltd 21 Mar 2019

Inflammation in the brain increases side-effects of hypnotic drugs

In a study recently published in the European Journal of Pharmacology researchers at Okayama University show how the presence of inflammation in the brain can increase its sensitivity to benzodiazepines.

7 Mar 2019

New strategy may alleviate motor disorders in Parkinson's patients

Scientists of the German Center for Neurodegenerative Diseases and the University Medical Center Goettingen have been able to alleviate motor disorders in mice that resemble those seen in Parkinson's patients.

28 Feb 2019

'Holy herb' (Yerba santa) identified as a potential treatment for Alzheimer’s disease

Yerba santa, also known as the ‘Holy Herb’, may have important implications for patients with Alzheimer’s disease.

22 Feb 2019

Discovery of potent compound in native California shrub may lead to treatment for Alzheimer's

The medicinal powers of aspirin, digitalis, and the anti-malarial artemisinin all come from plants. A Salk Institute discovery of a potent neuroprotective and anti-inflammatory chemical in a native California shrub may lead to a treatment for Alzheimer's disease based on a compound found in nature.

21 Feb 2019

Transplanting bone marrow of young mice into old mice prevents cognitive decline

A new study has found that transplanting the bone marrow of young laboratory mice into old mice prevented cognitive decline in the old mice, preserving their memory and learning abilities.

20 Feb 2019

Peripheral nerve injury can trigger the onset and spread of ALS, shows study

A growing collection of anecdotal stories raises the possibility that nerve injury in an arm or a leg can act as a trigger for the development amyotrophic lateral sclerosis, or ALS -- a progressive neurodegenerative disease also known as Lou Gehrig's disease, named after the famous New York Yankee who died of it in 1941.

20 Feb 2019

Researchers create new map of the brain's own immune system

A team of researchers under the direction of the Medical Center - University of Freiburg has created an entirely new map of the brain's own immune system in humans and mice.

19 Feb 2019

Researchers report promising advance in the search for new class of antidepressants

In experiments with mice, researchers at Johns Hopkins Medicine report a promising advance in the search for a new class of drugs to treat major depression.

8 Feb 2019

Advanced scan shows brain inflammation related to post-treatment Lyme disease syndrome

More than 1 in 10 people successfully treated with antibiotics for Lyme disease go on to develop chronic, sometimes debilitating, and poorly understood symptoms of fatigue and brain fog that may last for years after their initial infection has cleared up.

6 Feb 2019

Researchers identify treatable mechanism in patients with schizophrenia

For reasons that are unclear, schizophrenia patients have fewer connections between the neurons in the brain. Researchers at Karolinska Institutet, Sweden, and Massachusetts General Hospital, USA, have now succeeded in creating human cell models that show that there is an excessive degradation of connections in the brain of these patients, and they have been able to link this to a genetic risk variant for the disease.

4 Feb 2019

Defective molecular master switch could lead to age-related macular degeneration

A signaling pathway controlled by transforming growth factor beta (TGF-beta) could be involved in the progression of age-related macular degeneration.

22 Jan 2019

Research brings new hope to treating degenerative brain diseases

Alzheimer's disease is the most representative degenerative brain disease, accounting for 60 to 80% of all dementia cases. In search for new mechanism for AD, the research team led by Professor Seong-Woon Yu of Brain and Cognitive Sciences paid attention to the autophagy of microglia, brain immune cells, is suppressed by inflammation.

17 Jan 2019