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Holography helps tackle ovarian cancer

Two University of Arizona researchers have formed a research team to design, build and evaluate two versions of an ovarian cancer medical imaging and screening instrument that will use holographic components in a new type of optical microscope.

11 Aug 2009

Recruitment of new neurons slows when old brain cells kept from dying

Recruitment of new neurons slows when old brain cells kept from dying. Like clockwork, brain regions in many songbird species expand and shrink seasonally in response to hormones.

11 Aug 2009

New kind of “molecular condom” to protect women from AIDS

University of Utah scientists developed a new kind of “molecular condom” to protect women from AIDS in Africa and other impoverished areas. Before sex, women would insert a vaginal gel that turns semisolid in the presence of semen, trapping AIDS virus particles in a microscopic mesh so they can’t infect vaginal cells.

10 Aug 2009

$1 million grant to Rhode Island hospital for melanoma screening training program

Rhode Island Hospital dermatologist Martin Weinstock, MD, PhD, has received a $1 million, 2-year Team Science Award grant from the Melanoma Research Alliance to serve as principal investigator to develop a training program for primary care physicians to improve melanoma screening in primary care. The goal is to develop a web-based training module that will lead to earlier detection of melanoma and ultimately reduce the number of melanoma deaths by half.

6 Aug 2009

Stem cell technology innovation could reduce the number of animal experiments

Researchers from the University of Bath are embarking on a project to use stem cell technology that could reduce the number of animal experiments used to study conditions such as motor neurone disease.

4 Aug 2009

New bio-hybrid materials could be used as sensors, catalysts, drug-delivery systems, more

Bacteria play a role in myriad industrial processes from fermentation to cleaning up environmental pollution. But floating freely in solution, the microbial cells constantly multiply, generating biomass that must be removed periodically, causing downtime. Additionally, the microorganisms cannot be localized to a specific region of interest.

3 Aug 2009

New technique captures bacterial infection on film

Researchers have developed a new technique that allows them to make a movie of bacteria infecting their living host.

27 Jul 2009

University at Buffalo start-up provides innovative digital sperm analysis to infertile couples worldwide

Couples struggling with fertility problems have a new option for assessing their ability to have a child with the start-up of a new Buffalo-based company called LifeCell Dx, Inc. (LCDX).

27 Jul 2009

Camera-phone uses blood, saliva samples to diagnose disease

Researchers at the University of California, Berkeley, have developed a "prototype camera-phone mounted with a microscope" that can "magnify and photograph blood or saliva samples" for diagnosing diseases, the Canadian Press/Google.com reports.

22 Jul 2009

Migrant neuron: New imaging studies reveal mechanics of neuron migration

The development of the brain proceeds a little like the European settlement of North America. The earliest pioneers settled on the east coast with subsequent waves of settlers forming communities further and further westward. In cortical regions of the developing brain, generations of young neurons undergo a staged migration as well, with the earliest-born cells staying relatively close to their birthplace and subsequent generations traveling further, ultimately stratifying into six neuronal layers in the mature brain. Now, for the first time, imaging studies have identified the "motors" that propel a unique form of cell migration that creates these layers that

22 Jul 2009

IRIN examines efforts to improve sleeping sickness dectection

IRIN examines the efforts of the Geneva-based Foundation for Innovative New Diagnostics (FIND) to develop less costly surveillance equipment to improve the ability to detect the parasitic disease trypanosomiasis (sleeping sickness) in endemic countries.

16 Jul 2009

Identification of cholesterol regulating genes by targeted RNAi-screening

Scientists at the European Molecular Biology Laboratory (EMBL) and the University of Heidelberg, Germany, have come a step closer to understanding how cholesterol levels are regulated. In a study published today in the journal Cell Metabolism, the researchers identified 20 genes that are involved in this process. Besides giving scientists a better idea of where to look to uncover the mechanisms that ensure cholesterol balance is maintained, the discovery could lead to new treatments for cholesterol-related diseases.

7 Jul 2009

New prostate cancer metastasis prediction method

Cancer experts at Johns Hopkins say a study tracking 774 prostate cancer patients for a median of eight years has shown that a three-way combination of measurements has the best chance yet of predicting disease metastasis.

1 Jul 2009

Researchers using microRNA to identify aggressive melanoma

Research at the University of Leicester will be breaking new ground in the search for a simple blood test that could tell whether a patient with melanoma has the condition in an aggressive form.

30 Jun 2009

New understanding of how cells cover gaps

Researchers at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, came a step closer to understanding how cells close gaps not only during embryonic development but also during wound healing. Their study, published this week in the journal Cell, uncovers a fundamental misconception in the previous explanation for a developmental process called dorsal closure.

28 Jun 2009

Harnessing nanoparticles to track cancer cell changes

The more dots there are, the more accurate a picture you get when you connect them. Cancer researchers adopting that philosophy have developed a new imaging technology that could give scientists the ability to simultaneously measure as many as 100 or more distinct features in or on a single cell. In a disease such as cancer, that capability would provide a much better picture of what is going on in individual tumor cells.

28 Jun 2009

Cryo-electron tomography shows immature HIV in 3D

Scientists at the European Molecular Biology Laboratory (EMBL) and the University Clinic Heidelberg, Germany, have produced a three-dimensional reconstruction of HIV (Human Immunodeficiency Virus), which shows the structure of the immature form of the virus at unprecedented detail. Immature HIV is a precursor of the infectious virus, which can cause AIDS.

23 Jun 2009

Novel light-sensitive compounds show promise for photodynamic cancer therapy

Chemists at the University of California, Santa Cruz, have developed novel compounds that show promise for photodynamic cancer therapy, which uses light-activated drugs to kill tumor cells.

17 Jun 2009

Inflammation of microglia may not be associated with dementia in Alzheimer's disease

The idea that anti-inflammatory drugs might protect people struggling with dementia from Alzheimer's disease has received a blow with the online release of a study of human brain tissue in Acta Neuropathologica.

15 Jun 2009

Neuroscientists watch memories form in real time

Our ability to form long-term memories depends on cells in the brain making strong connections with each other. Yet while it's not well understood how those connections are made, lost or changed, the process is known to involve the movement of the AMPA receptor protein to and from those neuronal connections.

10 Jun 2009