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Morgridge researchers reveal complex viral replication process in unprecedented detail

In the fight against the viruses that invade everyday life, seeing and understanding the battleground is essential. Scientists at the Morgridge Institute for Research have, for the first time, imaged molecular structures vital to how a major class of viruses replicates within infected cells.

27 Jun 2017

Pathogen linked to seafood poisoning disarms key host defense system by paralyzing cell's skeleton

The leading cause of acute gastroenteritis linked to eating raw seafood disarms a key host defense system in a novel way: It paralyzes a cell's skeleton, or cytoskeleton.

23 Jun 2017

Researchers create new camera that can register fast processes in transparent specimens

Researchers from ITMO University have built a setup for recording holograms of tiny objects like living cells with a femtosecond speed. The new method allows one to reconstruct phase topography of a studied sample according to deformations that emerge in a laser pulse when it passes through the specimen.

22 Jun 2017

Researchers examine formation of functional amyloids by bacteria in real time

A team of scientists from the VIB lab of Han Remaut and the lab of Yves Dufrêne at UCL Louvain-La-Neuve collaborated on a study of functional amyloids -protein aggregates with the typical amyloid structure that do not lead to disease but rather serve a dedicated biological function.

21 Jun 2017

Francis Crick Institute selects Livecyte cell analysis system from Phasefocus

Phasefocus provides a range of products and services based on its proprietary Ptychographic Quantitative Phase Imaging (QPI) technology to provide a wide range of analytical applications including label-free cell imaging and quantitative electron phase microscopy. Here, they report on the Light Microscopy Science Technology Platform at the Francis Crick Institute’s selection of the Livecyte® label-free cell analysis system.

From Phase Focus Limited 19 Jun 2017

Near-atomic resolution 3D snapshots show how key biological machine unfolds problematic proteins

Hand over hand. That's how new, near-atomic resolution, 3-D snapshots show that a key biological machine unfolds a ribbon of protein through its central channel.

16 Jun 2017

Hidden immune cells play key role in driving primary graft dysfunction

Northwestern Medicine scientists have discovered that a subset of immune cells called nonclassical monocytes (NCMs), previously unknown to reside in the lungs, play a key role in driving primary graft dysfunction (PGD), the leading cause of death after lung transplantation.

15 Jun 2017

Molecule may play role in helping maintain balance of excitatory and inhibitory neurons

Many neurological diseases are malfunctions of synapses, or the points of contact between neurons that allow senses and other information to pass from finger to brain.

13 Jun 2017

Pyk2 deficits contribute to memory problems in Huntington’s disease mouse model

Researchers from the Institute of Neurosciences of the UB and from IDIBAPS together with a team from the University Pierre and Marie Curie and the Institute du Fer à Moulin, published a study in Nature Communications, which demonstrates that the regulation in Pyk2, a protein-tyrosine kinase, causes alterations of the synaptic plasticity involved in memory tasks, associated with the hippocampus in mouse models of neurodegenerative diseases, such as Huntington's.

13 Jun 2017

Digital, confocal and stereo microscopes highlighted by Zeiss at MD&M East Expo

ZEISS announces it will be highlighting powerful digital and stereo microscopes ideal for medical manufacturing quality control and assurance applications at Medical Design & Manufacturing (MD&M) East Expo and Conference, which takes place June 13-15, 2017 at the Jacob K. Javits Convention Center, in New York, NY. Visit Booth #2107 to see ZEISS Smartzoom 5 digital microscope and ZEISS Stemi 508 stereo microscope. Information on ZEISS Smartproof widefield confocal microscope will be part of a poster display at the booth.

From Carl Zeiss Microscopy GmbH 13 Jun 2017

Research reveals link between POMC neurons and release of insulin by the pancreas

The brain is key in the regulation of appetite, body weight and metabolism. Specifically, there is a small group of hypothalamus neurons, called POMC, that detect and integrate signals that inform on the energy state of the organism and activate the appropriate physiological responses.

8 Jun 2017

Can liver damage caused by a low protein diet be repaired?

Proteins are an important component of our diet and help to build muscles; they take part in the structure of hormones and they are vital to the whole body’s metabolism. The most important consequence is that the liver loses its capacity to produce proteins (such as albumin) and to metabolise (inactivate or activate in some cases) medicaments for instance.

8 Jun 2017

Researchers explore sea urchin protein to understand self-assembly of skeletal structures

Calcium carbonate, or CaCO3, comprises more than 4% of the earth's crust. Its most common natural forms are chalk, limestone, and marble, produced by the sedimentation of the shells of small fossilized snails, shellfish, and coral over millions of years.

8 Jun 2017

New protocol offers faster and more effective way to obtain astrocytes from stem cells

Neurons have long enjoyed the spotlight in neuroscience--and for good reason: they are incredibly important cellular actors. But, increasingly, star-shaped support cells called astrocytes are being seen as more than bit players in the brain's rich pageant.

6 Jun 2017

Mouse model could improve understanding of human brown fat’s role in metabolic processes

When it gets cold around you, your body turns up the heat to maintain its normal temperature. The heat is produced by brown adipose tissue, or brown fat, which also plays a role in how the body uses glucose and fat.

2 Jun 2017

Researchers uncover new way to enhance function of immune cells to combat multiple myeloma

Researchers from Belgium led by Prof. Dirk Elewaut of the VIB-UGent Center for Inflammation Research and the team of Prof. Vanderkerken and Prof. Menu at the Hematology and Immunology lab of the VUB uncovered a new way to enhance the function of a specific type of immune cell that destroys tumors in multiple myeloma, a form of bone marrow cancer considered incurable.

1 Jun 2017

Microscopy News and Research

Morgridge researchers reveal complex viral replication process in unprecedented detail

Pathogen linked to seafood poisoning disarms key host defense system by paralyzing cell's skeleton

Researchers create new camera that can register fast processes in transparent specimens

Researchers examine formation of functional amyloids by bacteria in real time

Francis Crick Institute selects Livecyte cell analysis system from Phasefocus

Near-atomic resolution 3D snapshots show how key biological machine unfolds problematic proteins

Hidden immune cells play key role in driving primary graft dysfunction

Molecule may play role in helping maintain balance of excitatory and inhibitory neurons

Pyk2 deficits contribute to memory problems in Huntington’s disease mouse model

Digital, confocal and stereo microscopes highlighted by Zeiss at MD&M East Expo

Research reveals link between POMC neurons and release of insulin by the pancreas

Can liver damage caused by a low protein diet be repaired?

Researchers explore sea urchin protein to understand self-assembly of skeletal structures

New protocol offers faster and more effective way to obtain astrocytes from stem cells

Mouse model could improve understanding of human brown fat’s role in metabolic processes

Researchers uncover new way to enhance function of immune cells to combat multiple myeloma

Single protein allows mycobacteria to generate diverse populations and avoid TB drugs, research shows

Leica introduces new DMi8 S solution for fast, versatile microscopic imaging of living cells

Researchers capture first cryo-EM snapshots of key cellular receptor in action

Researchers find relationship between insulin secretion machinery and calcium channels in diabetes

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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