Mitochondria News and Research

RSS

Breakthrough research opens door to potential new therapies for inflammatory diseases

Scientists have made a major breakthrough in understanding the workings of the cellular machinery involved in a host of inflammatory diseases.

24 Sep 2016

Mitochondrial alternative oxidase from sea-squirt shows potential to fight against sepsis

Mitochondrial alternative oxidase from a sea-squirt works as a safety valve for stressed mitochondria. This property enables it to stop the runaway inflammatory process that leads to multiple organ failure and eventual death in bacterial sepsis.

23 Sep 2016

Research findings point to potential new targeted therapy for SMA

For the first time, scientists found that in spinal muscular atrophy (SMA), the affected nerve cells that control muscle movement, or motor neurons, have defects in their mitochondria, which generate energy used by the cell.

15 Sep 2016

New study identifies potential therapeutic option for treatment of Huntington's disease

A new scientific study reveals one way to stop proteins from triggering an energy failure inside nerve cells during Huntington's disease. Huntington's disease is an inherited genetic disorder caused by mutations in the gene that encodes huntingtin protein.

14 Sep 2016

Researchers describe how genetic mutations cause unnamed neurological disorder

In rare cases -- for instance, among siblings in two families from Pakistan and Oman described in a new study -- children have been born with an unnamed neurological disorder.

6 Sep 2016

Discovery of signalling pathway could pave way for developing treatments targeting T-ALL leukaemia

Cooperation between Finnish and Chinese research groups has opened up new opportunities for developing treatments targeting aggressive acute lymphoblastic leukaemia (T-ALL).

2 Sep 2016

Foul smelling gas could help people with diabetes recover from heart complications

A gas that was formerly known for its noxious qualities could help people with diabetes recover from common heart and blood vessel complications, concludes research led by the University of Exeter Medical School.

1 Sep 2016

Texas Tech researcher examines how healthy brown fat can be activated in humans

Come fall, being a bear starts to look better and better. They load up on fat, sleep the winter away and wake up hungry.

1 Sep 2016

Whitehead Institute scientists develop novel method for profiling mitochondrial metabolites

Whitehead Institute scientists have developed a method to quickly isolate and systematically measure metabolite concentrations within the cellular organelles known as mitochondria, often referred to as the "powerhouses of the cell."

31 Aug 2016

UT Southwestern researchers identify protein that can kick-start more efficient, healthful breakdown of fat

Researchers at UT Southwestern Medical Center have found that a protein often located on the surface of fat droplets within cells - and especially abundant in the muscles of endurance athletes - can kick-start the more efficient and healthful breakdown of fat.

27 Aug 2016

TSRI study sheds light on how mitochondrial calcium can affect learning and memory

While calcium's importance for our bones and teeth is well known, its role in neurons—in particular, its effects on processes such as learning and memory—has been less well defined.

26 Aug 2016

UCSF researchers identify new strategy to cultivate beneficial energy-burning fat

UC San Francisco researchers studying beige fat — a calorie-burning tissue that can help to ward off obesity and diabetes — have discovered a new strategy to cultivate this beneficial blubber.

25 Aug 2016

Surgical repair of mitral valve may provide greater benefit in patients with no symptoms

A new study recently published in the Journal of Thoracic and Cardiovascular Surgery questions whether patients with isolated moderate to severe mitral valve regurgitation should receive treatment in earlier stages instead of waiting until symptoms appear.

25 Aug 2016

UT Southwestern researchers discover protein that can promote healthful breakdown of fat

25 Aug 2016

Novel innovation could help scientists study new treatments for mitochondrial diseases

A new study published in the Proceedings of the National Academy of Sciences from the University of Missouri has succeeded in creating embryos with "heteroplasmy," or the presence of both maternal and paternal mitochondrial DNA.

23 Aug 2016

Umbilical cells from babies of obese mothers show impaired expression of vital genes regulating metabolism

Scientists have long known that infants born to women who are obese show higher risks of obesity, but they don't fully understand what boosts those risks.

23 Aug 2016

Injecting omega-3 fatty acid reduces brain damage in neonatal mouse model of stroke

Researchers from Columbia University Medical Center found that omega-3 fatty acids reduced brain damage in a neonatal mouse model of stroke.

23 Aug 2016

Could nanotechnology turn the cancer cell suicide switch back on? An interview with Professor Dipanjan Pan

Before I explain the discovery, I would take a step back and explain an interesting event that takes place in the cancer cells. Normal cells follow a rapid and irreversible process to efficiently eradicate dysfunctional cells. This is a natural process by which damaged cells commit ‘suicide’. This process is known as apoptosis or programmed cell death.

15 Aug 2016

Specific molecular features control uptake of biguanides into mitochondria to inhibit respiration

The biguanides are a family of drugs with diverse clinical applications. Metformin, a widely used anti-hyperglycemic biguanide, suppresses mitochondrial respiration by inhibiting respiratory complex I. Phenformin, a related anti-hyperglycemic biguanide, also inhibits respiration, but proguanil, which is widely used for the prevention of malaria, does not.

12 Aug 2016

Pancreatic cancer cells find alternative source of nutrition to avoid starvation

Pancreatic cancer cells avert starvation in dense tumors by ordering nearby support cells to supply them with an alternative source of nutrition.

11 Aug 2016

Mitochondria News and Research

Breakthrough research opens door to potential new therapies for inflammatory diseases

Mitochondrial alternative oxidase from sea-squirt shows potential to fight against sepsis

Research findings point to potential new targeted therapy for SMA

New study identifies potential therapeutic option for treatment of Huntington's disease

Researchers describe how genetic mutations cause unnamed neurological disorder

Discovery of signalling pathway could pave way for developing treatments targeting T-ALL leukaemia

Foul smelling gas could help people with diabetes recover from heart complications

Texas Tech researcher examines how healthy brown fat can be activated in humans

Whitehead Institute scientists develop novel method for profiling mitochondrial metabolites

UT Southwestern researchers identify protein that can kick-start more efficient, healthful breakdown of fat

TSRI study sheds light on how mitochondrial calcium can affect learning and memory

UCSF researchers identify new strategy to cultivate beneficial energy-burning fat

Surgical repair of mitral valve may provide greater benefit in patients with no symptoms

UT Southwestern researchers discover protein that can promote healthful breakdown of fat

Novel innovation could help scientists study new treatments for mitochondrial diseases

Umbilical cells from babies of obese mothers show impaired expression of vital genes regulating metabolism

Injecting omega-3 fatty acid reduces brain damage in neonatal mouse model of stroke

Could nanotechnology turn the cancer cell suicide switch back on? An interview with Professor Dipanjan Pan

Specific molecular features control uptake of biguanides into mitochondria to inhibit respiration

Pancreatic cancer cells find alternative source of nutrition to avoid starvation

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Latest Life Science News