Molecular Biology News and Research

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Molecular biology is the study of biology at a molecular level. The field overlaps with other areas of biology and chemistry, particularly genetics and biochemistry. Molecular biology chiefly concerns itself with understanding the interactions between the various systems of a cell, including the interactions between DNA, RNA and protein biosynthesis as well as learning how these interactions are regulated.

USPTO rejects patent claims asserted against Precision BioSciences

Precision BioSciences, Inc., today announced that the United States Patent and Trademark Office (PTO) has issued Final Decisions and Right of Appeal Notices in the reexamination proceedings for U.S. Pat. Nos. 6,833252, 7,214,536, 6,610,545 and 7,309,605 that are owned by the Institut Pasteur and the Universite Pierre et Marie Curie, and licensed to Cellectis, SA (ALCLS).

28 Oct 2010

1000 Genomes Project publishes comprehensive map of genetic variations in Nature journal

Small genetic differences between individuals help explain why some people have a higher risk than others for developing illnesses such as diabetes or cancer. Today in the journal Nature, the 1000 Genomes Project, an international public-private consortium, published the most comprehensive map of these genetic differences, called variations, estimated to contain approximately 95 percent of the genetic variation of any person on Earth.

28 Oct 2010

IBI receives U.S. patent for novel blood protein biomarkers

Intrinsic Bioprobes today announced that the United States Patents and Trademark Office has issued US Patent 7,816,095 covering novel blood protein biomarkers related to cardiovascular disease. This patent is first of a series of patent applications that cover specific human protein variants as biomarkers with clinical utility.

28 Oct 2010

University of Padua Professor wins Paul Ehrlich and Ludwig Darmstaedter Prize

Frankfurt am Main. The chemist and biologist Professor Cesare Montecucco, 62, of the Department of Biomedical Research at the University of Padua, Italy, has won the 100,000 euro Paul Ehrlich and Ludwig Darmstaedter Prize 2011 for his contribution to research in the field of bacterial diseases, including tetanus, botulism, anthrax and Helicobacter pylori associated diseases.

27 Oct 2010

Pacific Biosciences prices initial public offering of common stock

Pacific Biosciences of California, Inc. developer of single molecule, real-time (SMRT) technology for biological analysis, announced today the pricing of its initial public offering of 12,500,000 shares of its common stock at $16.00 per share. All shares are being sold by the company.

27 Oct 2010

MDI and Westburg enter exclusive distribution agreement for Detect-Ready MRSA panel in Benelux region

Molecular Detection Inc. (MDI), a company developing Detect-Ready™ tests designed to increase the speed and accuracy of infectious disease diagnosis, and life sciences and diagnostics distributor Westburg BV today announced that they have entered into an exclusive agreement for distribution of MDI's Detect-Ready MRSA panel in the Benelux region.

26 Oct 2010

New feature on SciVerse ScienceDirect presents proteins in three dimensions

Elsevier, a world-leading publisher of scientific, medical and technical products and services, introduces Protein Viewer, a new, interactive feature on SciVerse ScienceDirect for the Journal of Molecular Biology (JMB). With Protein Viewer, readers of JMB now have the power to expand and rotate molecules within the actual article. SciVerse ScienceDirect merges features of the World Protein Database and Jmol, and embeds them into the article, making its use more convenient and user-friendly.

26 Oct 2010

BAFF protein can promote aggressive leukemia and lymphomas

Chronic lymphocytic leukemia (CLL) cells survive and thrive not just by their own innate wiles, but by also acquiring aid and support from host cells in their surrounding environment.

25 Oct 2010

Research on worms may help develop ways to maintain fertility in humans

Princeton scientists have identified genes responsible for controlling reproductive life span in worms and found they may control genes regulating similar functions in humans. The work suggests that someday researchers may be able to develop ways to maintain fertility in humans, allowing women who want to delay having children to preserve that capacity and extend their reproduction, and to prevent maternal age-related birth defects.

25 Oct 2010

Antigene therapy uses light energy to silence gene activity: Review article

Antigene therapy is a promising new treatment strategy that uses a DNA-based drug to pinpoint light energy to a target gene shutting down its activity.

22 Oct 2010

LabCorp third quarter revenues increase 7.7% to $1,276.5 million

Laboratory Corporation of America® Holdings today announced results for the quarter ended September 30, 2010.

21 Oct 2010

Matrix-Bio's VeraMarker-BCR blood test predicts breast cancer recurrence 13 months before clinical diagnosis

Connie Krabbe understands the fear and foreboding breast cancer survivors feel when visiting their physicians for post-treatment check-ups. Two of her four sisters died of metastatic cancer related to breast cancer, enduring bone, brain, and ovarian cancer before succumbing to the disease in their early 50s.

21 Oct 2010

Scientists find potential Achilles Heel in JC polyomavirus

The JC polyomavirus doesn't strike very often, but it's a mean bug that preys on people with weakened immune systems, including people with AIDS, and almost always kills them. Now an international team of scientists at Brown University, the University of T-bingen in Germany, and Imperial College in London has found a potential Achilles Heel and painted a target on it: The virus must bind to a very specific sugar molecule dangling from the side of the brain cells it attacks.

21 Oct 2010

Alexion announces results of eculizumab two open-label Phase 2 studies for aHUS treatment

Alexion Pharmaceuticals, Inc. today announced that its two open-label Phase 2 studies investigating eculizumab (Soliris) as a treatment for patients with atypical Hemolytic Uremic Syndrome (aHUS) have met the primary and key secondary endpoints with high clinical and statistical significance, in interim analyses.

21 Oct 2010

UTHSC-Houston initiates enrollment in NanoLogix technology trial for detection of GBS in pregnant women

NanoLogix, an innovator in the accelerated detection and identification of microorganisms, announced today that the University of Texas Health Science Center in Houston is enrolling 300 patients in an ongoing clinical trial to study the speed and accuracy of NanoLogix technology. The trial is designed to compare NanoLogix technology to current methods in use for detection and identification of Group B Streptococcus (GBS) in pregnant women.

20 Oct 2010

Scientists probe functional connectivity among neurons in auditory cortex gives rise to map of acoustic space

Just as we visually map a room by spatially identifying the objects in it, we map our aural world based on the frequencies of sounds. The neurons within the brain's "hearing center"-the auditory cortex-are organized into modules that each respond to sounds within a specific frequency band. But how responses actually emanate from this complex network of neurons is still a mystery.

19 Oct 2010

'Sister' mitral cells may broadcast 2 distinct channels of information on odors to cortex

A team co-led by neuroscientists at Cold Spring Harbor Laboratory (CSHL) has shed light -- literally -- on circuitry underlying the olfactory system in mammals, giving us a new view of how that system may pull off some of its most amazing feats.

19 Oct 2010

MPI of Biochemistry and GSK collaborate in development of new drugs for type 2 diabetes

The recently signed cooperation agreement between the MPI of Biochemistry and GSK pursues the objective of developing innovative new drugs. The joint research and development work is based on the research findings of Axel Ullrich, Director at the MPI of Biochemistry.

19 Oct 2010

Researchers identify new mechanism that could help develop effective chemotherapy drug

Information on proteins is critical for understanding how cells function in health and disease. But while regular proteins are easy to extract and study, it is far more difficult to gather information about membrane proteins, which are responsible for exchanging elements essential to our health, like copper, between a cell and its surrounding tissues.

19 Oct 2010

Researchers to identify protein-recycling mechanism of TB bacteria

Scientists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory and Stony Brook University have discovered a key difference in the way human cells and Mycobacterium tuberculosis bacteria, which cause TB, deliver unwanted proteins marked with a "kiss of death" sequence to their respective cellular recycling factories.

18 Oct 2010

Molecular Biology News and Research

Further Reading

USPTO rejects patent claims asserted against Precision BioSciences

1000 Genomes Project publishes comprehensive map of genetic variations in Nature journal

IBI receives U.S. patent for novel blood protein biomarkers

University of Padua Professor wins Paul Ehrlich and Ludwig Darmstaedter Prize

Pacific Biosciences prices initial public offering of common stock

MDI and Westburg enter exclusive distribution agreement for Detect-Ready MRSA panel in Benelux region

New feature on SciVerse ScienceDirect presents proteins in three dimensions

BAFF protein can promote aggressive leukemia and lymphomas

Research on worms may help develop ways to maintain fertility in humans

Antigene therapy uses light energy to silence gene activity: Review article

LabCorp third quarter revenues increase 7.7% to $1,276.5 million

Matrix-Bio's VeraMarker-BCR blood test predicts breast cancer recurrence 13 months before clinical diagnosis

Scientists find potential Achilles Heel in JC polyomavirus

Alexion announces results of eculizumab two open-label Phase 2 studies for aHUS treatment

UTHSC-Houston initiates enrollment in NanoLogix technology trial for detection of GBS in pregnant women

Scientists probe functional connectivity among neurons in auditory cortex gives rise to map of acoustic space

'Sister' mitral cells may broadcast 2 distinct channels of information on odors to cortex

MPI of Biochemistry and GSK collaborate in development of new drugs for type 2 diabetes

Researchers identify new mechanism that could help develop effective chemotherapy drug

Researchers to identify protein-recycling mechanism of TB bacteria

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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