Molecular Biology News and Research

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Molecular biology is the study of biology at a molecular level. The field overlaps with other areas of biology and chemistry, particularly genetics and biochemistry. Molecular biology chiefly concerns itself with understanding the interactions between the various systems of a cell, including the interactions between DNA, RNA and protein biosynthesis as well as learning how these interactions are regulated.

New target for muscular dystrophy drug therapy

Researchers at the University of Pennsylvania School of Medicine report how the gene for utrophin, which codes for a protein very similar to dystrophin, the defective protein in Duchenne muscular dystrophy (DMD), puts the brakes on its own expression in muscle cells, thereby suggesting a new target for treatment.

13 Jul 2007

Genes play a large role in sour taste perception

Scientists at the Monell Chemical Senses Center report that genes play a large role in determining individual differences in sour taste perception.

12 Jul 2007

How immune cells catch pathogens

To protect us from disease our immune system employs macrophages, cells that roam our body in search of disease-causing bacteria.

12 Jul 2007

Cancer-causing enzyme could be stopped

Scientists from the MRC's Laboratory of Molecular Biology (LMB) and the Albert Einstein College of Medicine have discovered a way to stop an enzyme responsible for many cancers.

11 Jul 2007

How immune cells catch pathogens

To protect us from disease our immune system employs macrophages, cells that roam our body in search of disease-causing bacteria. With the help of long tentacle-like protrusions, macrophages can catch suspicious particles, pull them towards their cell bodies, internalise and destroy them.

11 Jul 2007

Autophagy may accelerate decompensated heart failure

Autophagy, a normal process by which cells eat their own proteins to provide needed resources to the body in times of stress, may paradoxically cause harm to hearts already weakened by disease, researchers from UT Southwestern Medical Center have found.

9 Jul 2007

Orlistat weight loss drug points to new cancer treatments

Based on their surprising discovery that an obesity drug can kill cancer cells, scientists at Wake Forest University School of Medicine have made a new finding about the drug's effects and are working to design more potent cancer treatments.

9 Jul 2007

Amoebae control cheating by keeping it in the family

No one likes a cheater, even a single-celled one. New research from Rice University shows how cooperative single-celled amoebae rely on family ties to keep cheaters from undermining the health of their colonies.

9 Jul 2007

Gene found that protects from serious kidney disease

A combination of mice and patient studies sheds light on cause and possible new therapies of kidney diseases.

8 Jul 2007

Key finding on ALS related protein

Chemists from UCLA and the University of Florence in Italy may have solved an important mystery about a protein that plays a key role in a particular form of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, a progressive, fatal neurodegenerative disorder that strikes without warning.

28 Jun 2007

Australian scientists discover new reovirus

CSIRO scientists have played a key role in discovering that bats are the likely host of a new virus that can cause a serious but apparently non-fatal respiratory tract illness in humans.

28 Jun 2007

Breakthrough in understanding of noroviruses

A breakthrough announced this week by scientists at the University of Southampton's School of Medicine will lead to greater understanding of noroviruses, the most common cause of non-bacterial gastroenteritis around the world.

27 Jun 2007

Amphinase molecule from frog could provide first drug treatment for brain tumours

A synthetic version of a molecule found in the egg cells of the Northern Leopard frog (Rana pipiens) could provide the world with the first drug treatment for brain tumours.

27 Jun 2007

Call for global push to advance research in synthetic biology

With research backgrounds ranging from materials engineering to molecular biophysics, seventeen leading scientists issued a statement announcing that, much as the discovery of DNA and creation of the transistor revolutionized science, there is a new scientific field on the brink of revolutionizing our approach to problems ranging from eco-safe energy to outbreaks of malaria.

26 Jun 2007

Roche makes offer to acquire Ventana Medical Systems

Roche will make a tender offer to acquire all outstanding shares of common stock of Ventana Medical Systems for $75.00 per share in cash, or an aggregate of approximately $3 billion on a fully diluted basis.

From Roche Sequencing and Life Science 26 Jun 2007

Evolutionary dynamics of immune-related genes and pathways in disease vector mosquitoes

The genes that make up the immune system of the Aedes aegypti mosquito which transmits deadly viral diseases to humans have been identified in new research in Science.

23 Jun 2007

New compound kills fungal pathogens

A new mechanism to attack hard-to-treat fungal infections has been revealed by scientists from the biotech company Anacor Pharmaceuticals Inc., California, and the European Molecular Biology Laboratory (EMBL) outstation in Grenoble, France.

23 Jun 2007

Anacor finds novel mechanism for lead anti-fungal drug, AN2690

Anacor Pharmaceuticals, a privately held pharmaceutical company, has announced that the journal Science will publish results of research that details how AN2690, the company's lead clinical candidate, kills fungal cells by interfering with synthesis of a specific protein required for fungal growth.

23 Jun 2007

True nature of heterochromatin revealed

Not so long ago, the difficult-to-sequence, highly repetitive, gene-poor DNA found in regions of chromosomes known as heterochromatin was called "junk." Like dark matter in the universe, the true nature of heterochromatin was unknown.

19 Jun 2007

Rogue cells found that could cause spread of breast cancer

Stephanie Lebret completed the study for her PhD at Deakin's Centre for Cellular and Molecular Biology under the supervision of Associate Professor Leigh Ackland.

17 Jun 2007