Molecular Biology News and Research

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Molecular biology is the study of biology at a molecular level. The field overlaps with other areas of biology and chemistry, particularly genetics and biochemistry. Molecular biology chiefly concerns itself with understanding the interactions between the various systems of a cell, including the interactions between DNA, RNA and protein biosynthesis as well as learning how these interactions are regulated.

Structure of bacteriophage shown to resemble a human virus

New research has revealed that the structure of a bacteriophage, a virus infecting bacteria, resembles that of certain dangerous viruses that infect people.

26 Jun 2006

Scientists cracking virus protection shield

Scientists reveal the structure of a protein that packages the viral genome and helps viruses to replicate while avoiding human immune reactions

18 Jun 2006

Central nervous system can sometimes send out signals that invite hostile immune system attacks

It may sound like a case of blame the victim, but researchers at Washington University School of Medicine in St. Louis have shown that cells in the central nervous system can sometimes send out signals that invite hostile immune system attacks.

18 Jun 2006

Sonic hedgehog may help overcome problems associated with FGF2 and VEGF therapy

The newest concept for treating coronary artery disease is to induce hearts to grow their own new blood vessels to bypass damaged tissue or clogged arteries.

18 Jun 2006

Burkitt lymphoma gene expression signature identified

An international research study involving the University of Nebraska Medical Center, the National Cancer Institute and 10 other institutions has successfully identified the gene expression signature for Burkitt lymphoma.

14 Jun 2006

Research explains how pathogenic bacteria evolved over millions of years

Bacteria like Salmonella have a complicated immune system that helps them recognize and isolate foreign DNA trying to invade their cell membrane, according to a University of Washington-led study in the June 8 issue of Science Express.

9 Jun 2006

Milstein gift seeks cure for antibiotic-resistant TB and malaria

A $7.25 million gift to Weill Medical College of Cornell University will establish the Abby and Howard P. Milstein Chemistry Core Facility and the Abby and Howard P. Milstein Program in Chemical Biology.

5 Jun 2006

German scientists synthesize new compound that reduces stroke damage

A group of German scientists has synthesized a new compound that dramatically decreases the damage to neurons in rats demonstrating stroke symptoms.

16 May 2006

First animal model that mimics human head and neck cancer

An Oregon Health & Science University Cancer Institute research laboratory has developed a novel mouse model designed specifically to study the often devastating head and neck squamous cell cancers.

16 May 2006

Promising chemo, therapeutic viruses, cutting-edge surgery debut at M. D. Anderson Cancer Center

Brain tumor specialists at The University of Texas M. D. Anderson Cancer Center are poised on the brink of a new era.

10 May 2006

"Junk" RNA regulates important cellular processes

It has been known for a long time that much of a cell’s RNA stems from DNA regions called intergenic spacers (IGS) that lie between two genes and do not code for proteins.

9 May 2006

Bacterial binding in the stomach

Scientists have determined that decay-accelerating factor (DAF), a protein found in epithelial cells in the stomach, acts as a receptor for the bacteria Helicobacter pylori. Blocking this interaction could lead to new drugs that reduce the risk of peptic ulcer disease or gastric cancer.

8 May 2006

Important insights into how cells regulate certain growth-proteins

Researchers here have discovered a new mechanism used by cells - and manipulated by retroviruses - to control the making of certain essential proteins, including some involved in cancer.

8 May 2006

Genetic and environmental factors impact chronic fatigue syndrome patients

People who suffer from chronic fatigue syndrome (CFS) have a genetic make up that affects the body's ability to adapt to change, according to a series of papers released last week by the Centers for Disease Control and Prevention (CDC).

2 May 2006

Tumour specific drugs may render therapies based on a tumor's anatomical location obsolete

The results of a new study at Washington University School of Medicine in St. Louis could eventually have oncologists removing their specialties from their shingles by making therapy based on a tumor's anatomical location obsolete.

28 Apr 2006

Enzyme discovery could reduce Kaposi sarcoma tumour growth and lead to drugs suitable for treating other viral cancers

A report in the Journal of Biological Chemistry shows that inhibition of heme oxygenase-1, an enzyme involved in iron metabolism, reduces Kaposi sarcoma tumor growth. This discovery could result in the production of new drugs to treat this and other viral cancers.

28 Apr 2006

WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing

A team of scientists from Lawrence Berkeley National Laboratory and the Scripps Research Institute has determined the crystal structure and molecular mechanisms of a key part of WRN, a protein that protects humans from premature aging and cancer.

23 Apr 2006

Australian scientists tackle deadly Q fever

Scientists at James Cook University have taken the lead in developing a new vaccine against a highly infectious cattleyard disease caused by a bacteria which has the potential to be developed as a bioterrorist weapon.

20 Apr 2006

Getting to the heart of cardiovascular diseases

A new collaboration covers the spectrum from molecules to therapies. Three research organisations have announced the merging of their expertise to fight cardiovascular diseases, which are among the most common health problems and causes of death in the world.

13 Apr 2006

Caenorhabditis elegans helps unravel mechanisms of hunger

In research that may have implications for studying eating disorders in humans, a worm the size of a pinhead is helping researchers at UT Southwestern Medical Center unravel the mechanisms of hunger.

6 Apr 2006