Monoclonal Antibody News and Research

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Monoclonal antibodies (MAbs) are produced from a single B cell clone and can bind to a single type of antigen binding site. MAbs are homogenous antibodies that cannot form lattices with monomeric proteins as they can bind to only a single epitope on the antigen. Developed in the 1970s, MAbs can be produced against any given substance. Thus they can be used to detect and purify any substance of interest. This has made MAbs a powerful tool of molecular biology, biochemistry, and medicine.
Pre-existing SARS-CoV-2 antibodies may increase the breadth of mRNA vaccines, study suggests

Pre-existing SARS-CoV-2 antibodies may increase the breadth of mRNA vaccines, study suggests

Mucosal IgA fused nanobody as a non-invasive, cost-effective prophylaxis and therapeutic option against major SARS-CoV-2 variants

Mucosal IgA fused nanobody as a non-invasive, cost-effective prophylaxis and therapeutic option against major SARS-CoV-2 variants

Prior infection and vaccination protects against severe outcomes from SARS-CoV-2 Omicron infection

Prior infection and vaccination protects against severe outcomes from SARS-CoV-2 Omicron infection

The antibody resistance profile and viral receptor binding affinity of SARS-CoV-2 Omicron BQ.1, BQ.1.1, XBB, and XBB.1 subvariants

The antibody resistance profile and viral receptor binding affinity of SARS-CoV-2 Omicron BQ.1, BQ.1.1, XBB, and XBB.1 subvariants

Researchers use a comparative study to model RSV prevention in children

Researchers use a comparative study to model RSV prevention in children

Sino Biological announces construction of its new US-based center for bioprocessing

Sino Biological announces construction of its new US-based center for bioprocessing

Plant-based monoclonal antibody increases potency of antibody cocktail against SARS-CoV-2 Omicron variant

Plant-based monoclonal antibody increases potency of antibody cocktail against SARS-CoV-2 Omicron variant

Approved and developing passive and active immunizations against respiratory syncytial virus in childhood and pregnancy

Approved and developing passive and active immunizations against respiratory syncytial virus in childhood and pregnancy

UC San Diego receives $8 million CIRM funding to expedite stem cell therapy clinical trials

UC San Diego receives $8 million CIRM funding to expedite stem cell therapy clinical trials

FDA approves first-ever type 1 diabetes delaying drug Tzield (teplizumab-mzwv)

FDA approves first-ever type 1 diabetes delaying drug Tzield (teplizumab-mzwv)

Among US veterans with COVID-19, few used antivirals or monoclonal antibodies

Among US veterans with COVID-19, few used antivirals or monoclonal antibodies

Research findings could bolster the effectiveness of immune-checkpoint therapy

Research findings could bolster the effectiveness of immune-checkpoint therapy

Utilizing marine sources to extract DHA to treat Alzheimer’s

Utilizing marine sources to extract DHA to treat Alzheimer’s

First placebo-controlled long-term trial of anifrolumab shows positive results in patients with lupus

First placebo-controlled long-term trial of anifrolumab shows positive results in patients with lupus

Novel monoclonal antibodies NA8 and NE12 can neutralize most SARS-CoV-2 variants and Omicron subvariants

Novel monoclonal antibodies NA8 and NE12 can neutralize most SARS-CoV-2 variants and Omicron subvariants

Study explores the potential use of anti-thymic stromal lymphopoietin monoclonal antibody as an adjuvant in allergic immunotherapy

Study explores the potential use of anti-thymic stromal lymphopoietin monoclonal antibody as an adjuvant in allergic immunotherapy

New control system could be used to finely tune the production of useful proteins

New control system could be used to finely tune the production of useful proteins

Progress and challenges in the development of mRNA vaccines against respiratory syncytial virus

Progress and challenges in the development of mRNA vaccines against respiratory syncytial virus

Monoclonal antibody shows efficacy in preventing malaria infection in African adults

Monoclonal antibody shows efficacy in preventing malaria infection in African adults

New insights on antibody response against SARS-CoV-2 Omiron sublineages

New insights on antibody response against SARS-CoV-2 Omiron sublineages