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More AIDS-defining illnesses and severe side effects occur with appropriate comparator therapy

The drug combination of elvitegravir, cobicistat, emtricitabine and tenofovir disoproxil (elvitegravir fixed combination, trade name: Stribild) has been approved in Germany since May 2013 for the treatment of adults infected with human immunodeficiency virus type 1 (HIV-1).

21 Sep 2013

Blood pressure cuffs reduce subsequent cardiac symptoms, mortality after acute heart attack

In patients with an acute heart attack, remote ischemic conditioning - intermittent inflation of a blood pressure cuff to cut off blood flow to the arm during transportation to hospital for acute balloon dilatation - reduces subsequent cardiac symptoms and mortality after acute heart attack.

21 Sep 2013

Equatorial Guinea presents design for malaria vaccine trial

Equatorial Guinea's Ministry of Health and Social Security recently presented a design for a malaria vaccine trial as part of the government's efforts to improve the country's public health.

21 Sep 2013

Digoxin linked with higher rate of death among adults with diagnosed systolic heart failure

Digoxin, a drug commonly used to treat heart conditions, was associated with a 72 percent higher rate of death among adults with newly diagnosed systolic heart failure, according to a Kaiser Permanente study that appears in the current online issue of Circulation: Cardiovascular Quality and Outcomes.

21 Sep 2013

Older adults who gain little weight live longer

Some overweight older adults don't need to lose weight to extend their lives, but they could risk an earlier death if they pack on more pounds.

20 Sep 2013

GW researcher awarded UO-1 grants to study gut microbiome on inflammation, cardiovascular disease

Dominic Raj, M.D., director of the division of nephrology and professor of medicine at the George Washington University School of Medicine and Health Sciences, was the recipient of two prestigious UO-1 grants from the National Institutes of Health.

20 Sep 2013

Hormone replacement therapy formulations may cause different risks for stroke, heart attack

Post-menopausal women whose doctors prescribe hormone replacement therapy for severe hot flashes and other menopause symptoms may want to consider taking low doses of Food and Drug Administration-approved bioidentical forms of estrogen or getting their hormones via a transdermal patch.

20 Sep 2013

Study explains indirect burden of malaria on childhood deaths

Recurrent episodes of malaria cause chronic inflammation in blood vessels that might predispose to future infections and may increase susceptibility to cardiovascular disease, a Wellcome Trust study in Malawian children finds.

20 Sep 2013

Scientists are preparing for possible pandemic spread of new bird flu strain

Scientists at Saint Louis University are preparing for the potential pandemic spread of a new bird flu strain that caused severe disease in China last spring, joining researchers from seven other Vaccine and Treatment Evaluation Units funded by the National Institutes of Health (NIH) to test vaccines to protect against the illness in adults.

20 Sep 2013

Orbeshield Earns Soligenix Up To $26.3M From BARDA

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19 Sep 2013

Isis Pharmaceuticals announces preliminary data from ISIS-SMNRx Phase 1 study in infants with SMA

Isis Pharmaceuticals, Inc. announced today that follow-up preliminary data from a single dose, open-label Phase 1 study of ISIS-SMNRx in children with spinal muscular atrophy, show that most SMA children receiving the two highest doses of the drug (6 mg and 9 mg) continued to show improvements in muscle function tests up to 14 months after a single injection of the drug.

19 Sep 2013

Researchers identify two accurate predictors of short-term mortality

Having the right tool to estimate surgical risk in patients at high risk for complications and death during and after surgery is crucially important, according to a study in the October issue of Anesthesiology.

19 Sep 2013

Comprehensive changes in lifestyle could reverse ageing

A pilot study, published in The Lancet Oncology, shows that comprehensive lifestyle changes may increase the length of telomeres, the ends of chromosomes that control cell ageing.

19 Sep 2013

Study: Countries with lower gun ownership are safer than those with higher gun ownership

A new study reports that countries with lower gun ownership are safer than those with higher gun ownership, debunking the widely quoted hypothesis that guns make a nation safer.

19 Sep 2013

Cardiovascular mortality in schizophrenia may be underestimated

Cardiovascular causes account for about a quarter of deaths of patients with schizophrenia and may also contribute to the high rate of unexplained deaths, say researchers.

17 Sep 2013

Boston Scientific announces positive results from REPRISE II clinical trial of Lotus Valve System

Boston Scientific Corporation reported favorable six-month results from the first 60 patients enrolled in the REPRISE II clinical trial evaluating the safety and performance of the Lotus™ Valve System in symptomatic patients with severe aortic stenosis considered at high risk for surgical valve replacement.

17 Sep 2013

Study reports identification of IDH1 protein as novel biomarker for diagnosis of NSCLC

A protein called isocitrate dehydrogenase is present at high levels in lung cancers and can be detected in the blood, making it a noninvasive diagnostic marker for lung cancers, according to a study published in Clinical Cancer Research, a journal of the American Association for Cancer Research.

17 Sep 2013

Arginine therapy may be safe treatment for patients with sickle cell disease

Arginine therapy may be a safe and inexpensive treatment for acute pain episodes in patients with sickle cell disease, according to results of a recent clinical study. The study was the first randomized placebo-controlled study to demonstrate benefits of arginine therapy in children with sickle cell disease hospitalized for severe pain.

17 Sep 2013

Study: Opioid prescribing for non-cancer pain increases

Prescribing of strong opioid medications for non-cancer pain in the United States has nearly doubled over the past decade, reports a study in the October issue of Medical Care, published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

16 Sep 2013

$MatrixRIB MIPO instrumentation from DePuy Synthes CMF is more effective for rib fractures$

MatrixRIB MIPO instrumentation from DePuy Synthes CMF is more effective for rib fractures

DePuy Synthes CMF, a leader in skeletal and soft tissue repair and reconstruction, announced the launch of new instrumentation that enables less invasive surgical fixation and stabilization of rib fractures with the company's MatrixRIB System of precontoured, low-profile titanium plates, locking screws and intramedullary splints.

13 Sep 2013

Mortality News and Research

More AIDS-defining illnesses and severe side effects occur with appropriate comparator therapy

Blood pressure cuffs reduce subsequent cardiac symptoms, mortality after acute heart attack

Equatorial Guinea presents design for malaria vaccine trial

Digoxin linked with higher rate of death among adults with diagnosed systolic heart failure

Older adults who gain little weight live longer

GW researcher awarded UO-1 grants to study gut microbiome on inflammation, cardiovascular disease

Hormone replacement therapy formulations may cause different risks for stroke, heart attack

Study explains indirect burden of malaria on childhood deaths

Scientists are preparing for possible pandemic spread of new bird flu strain

Orbeshield Earns Soligenix Up To $26.3M From BARDA

Isis Pharmaceuticals announces preliminary data from ISIS-SMNRx Phase 1 study in infants with SMA

Researchers identify two accurate predictors of short-term mortality

Comprehensive changes in lifestyle could reverse ageing

Study: Countries with lower gun ownership are safer than those with higher gun ownership

Cardiovascular mortality in schizophrenia may be underestimated

Boston Scientific announces positive results from REPRISE II clinical trial of Lotus Valve System

Study reports identification of IDH1 protein as novel biomarker for diagnosis of NSCLC

Arginine therapy may be safe treatment for patients with sickle cell disease

Study: Opioid prescribing for non-cancer pain increases

MatrixRIB MIPO instrumentation from DePuy Synthes CMF is more effective for rib fractures

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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