Motor Neurons News and Research

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Eradicating polio a better option than extended control of the disease

Concerns about the high perceived costs of eradicating the relatively low number of polio cases worldwide have led to recent suggestions that it is time to shift from a goal of eradication to control—abandoning eradication and allowing wild poliovirus to continue to circulate, which proponents of control believe can sustain the low number of cases.

15 Apr 2007

A wavering commitment to polio eradication is not a good option!

Concerns about the high perceived costs of eradicating the relatively low number of polio cases worldwide have led to recent suggestions that it is time to shift from a goal of eradication to control-abandoning eradication and allowing wild poliovirus to continue to circulate, which proponents of control believe can sustain the low number of cases.

12 Apr 2007

Stanford technique directly controls brain cell activity with light

Every thought, feeling and action originates from the electrical signals emitted by diverse brain cells enmeshed in a tangle of circuits.

5 Apr 2007

Curry related compound shows promise against Kennedy's disease

Scientists who focus on the molecular signaling that underlies prostate cancer have discovered a compound that shows promise against a debilitating neurodegenerative condition known as Kennedy's disease, which is caused by a mutant gene.

21 Mar 2007

Promising therapy for Lou Gehrig's disease delivers antisense drug directly to nervous system

Researchers have designed and tested a molecular therapy in animals that they hope will be a major development in the fight to treat amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease.

27 Jul 2006

Scientists identify signals that regulate the formation of spinal marrow

A team of researchers at Umea University in Sweden under the leadership of Thomas Edlund, Umea Center for Molecular Medicine, is now publishing their discovery of the signal molecules that regulate the formation of spinal marrow during the fetal period.

17 Jul 2006

Scientists use embryonic stem cells to awaken latent motor nerve repair

In a dramatic display of stem cells' potential for healing, a team of Johns Hopkins scientists reports that they've engineered new, completed, fully-working motor neuron circuits - neurons stretching from spinal cord to target muscles - in paralyzed adult animals.

26 Jun 2006

New roles for growth factors

During embryonic development, nerve cells hesitantly extend tentacle-like protrusions called axons that sniff their way through a labyrinth of attractive and repulsive chemical cues that guide them to their target.

18 Jun 2006

Mechanism for neurodenegerative diseases linked to transport proteins

Hampering the transport of proteins within cells may underlie several adult-onset neurodegenerative diseases, such as Huntington's, ALS and Kennedy disease. Understanding how this cell transport is blocked in these diseases may offer targets for future therapy.

9 Jun 2006

Search for gene search for sporadic amyotrophic lateral sclerosis

Though it's the more common form of the disease, sporadic Amyotrophic Lateral Sclerosis (ALS), which affects roughly 90 percent of those living with the fatal neurodegenerative illness, has been the one less studied, simply because, unlike familial ALS, no genes have turned up.

17 May 2006

New approaches to genetic disease, based on cells' own ability to correct themselves

New approaches to genetic disease, based on cells' own ability to correct themselves, will be outlined today at the annual conference of the European Society of Human Genetics in Amsterdam, The Netherlands.

8 May 2006

Ketogenic diet may prevent the progression of amyotrophic lateral sclerosis

A recent study directed by the Mount Sinai School of Medicine suggests a ketogenic- high caloric diet may prevent the progression of Amyotrophic Lateral Sclerosis (ALS).

18 Apr 2006

Cognitive impairment appears to be common in Lou Gehrig disease

In a study of 40 patients with amyotrophic lateral sclerosis (ALS), about one-third showed evidence of cognitive impairment, but these deficits did not appear to be related to survival, according to a study in the March issue of Archives of Neurology.

15 Mar 2006

Thalidomide, Lenalidomide show promise against Lou Gehrig's disease

New animal research suggests that two well-studied drugs, thalidomide and its derivative, lenalidomide, might extend the survival of patients with the neurological disorder amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease.

9 Mar 2006

Important milestone in understanding the neural circuitry that coordinates walking movements

Researchers at the Salk Institute for Biological Studies have identified an important circuit in the spinal cord that controls the speed with which our leg muscles contract and relax.

9 Mar 2006

Case biologists move closer to biologically inspired robots

The brain as command center for bodily movement was too simple an idea, thought the Russian physiologist Nicolas Bernstein some 60 years ago.

9 Feb 2006

Researchers uncover new toxic mechanism in ALS - Lou Gehrig's disease

Exactly how ALS - Lou Gehrig's disease - damages motor neurons is one of medical science's lingering mysteries. At least six mishaps within cells appear to contribute to the death of the nerves that enable muscle movement, but nothing stands out as the key problem.

6 Jan 2006