Motor Neurons News and Research

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Scientists find promising drug candidates for treatment of motor neurone disease

Scientists have taken a significant step forward in the search to find effective new drug candidates for the treatment of motor neurone disease.

1 Sep 2020

Inhibiting STING activation could be new therapeutic strategy to treat ALS and FTD

Alberto Yáñez Boyer, Ramón y Cajal researcher at BIOTECMED (Interdisciplinary Research Structure in Biotechnology and Biomedicine) and the Department of Microbiology and Ecology at the University of Valencia (UV), participates in a study on the C9orf72 gene and its mutations in the immune system.

28 Aug 2020

Study examines safety and early outcomes of gene therapy for spinal muscular atrophy

In May 2019, the U.S. Food and Drug Administration approved a gene replacement therapy for the inherited, progressive neuromuscular disease 5q-linked spinal muscular atrophy.

25 Aug 2020

Combining expertise in organoids and sequencing technologies for ALS research

MDC researchers received a $150,000 pilot project grant from the Chan Zuckerberg Initiative's Neurodegeneration Challenge Network to investigate a defining feature of amyotrophic lateral sclerosis (ALS).

20 Aug 2020

Study fills crucial knowledge gaps on myasthenia gravis

A study of 181 patients at 16 sites across the country who test negative for two antibodies long known to cause muscle-weakening myasthenia gravis, found that about 15% test positive for one of two newly discovered antibodies that also attack the point of communication between nerves and muscle.

19 Aug 2020

FDA approves first oral drug for treatment of spinal muscular atrophy

The U.S. Food and Drug Administration today approved Evrysdi (risdiplam) to treat patients two months of age and older with spinal muscular atrophy (SMA), a rare and often fatal genetic disease affecting muscle strength and movement.

7 Aug 2020

Study: Early training of cell development and network improves response

When it comes to training neural circuits for tissue engineering or biomedical applications, a new study suggests a key parameter: Train them young.

7 Aug 2020

Neuronal subtypes that drive locomotion in fruit fly reveal an unexpected diversity

A new study by MIT neuroscientists into how seemingly similar neuronal subtypes drive locomotion in the fruit fly revealed an unexpected diversity as the brain's commands were relayed to muscle fibers.

8 Jul 2020

Researchers discover new mechanism to explain the effects of subcortical strokes

IBS researchers have discovered a new mechanism to explain the effects of subcortical strokes and a new possible therapeutic approach.

7 Jul 2020

German researchers recommend early screening and treatment for spinal muscular atrophy

The advent of therapeutic interventions for spinal muscular atrophy (SMA) has increased the importance of presymptomatic diagnosis and treatment. When to start treatment in children with less severe disease remains controversial.

11 Jun 2020

Botox can be an effective treatment for certain sports injuries

While botulinum toxin is commonly known as a cosmetic treatment for facial lines and wrinkles, a growing body of evidence suggests that "Botox" can also be an effective treatment for certain sports injuries and chronic pain conditions, according to a review in the June issue of Current Sports Medicine Reports, official journal of the American College of Sports Medicine.

9 Jun 2020

Research suggests new approach to therapeutic intervention for ALS

Amyotrophic lateral sclerosis (ALS) is one of the most devastating adult-onset neurodegenerative diseases. Patients, including the late actor/playwright Sam Shepard, become progressively weaker and eventually paralyzed as their motor neurons degenerate and die.

1 Jun 2020

Study provides groundwork for restoring nerve-muscle connection in ALS

Patients with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, lose muscle control as nerve cells or neurons in the brain and spinal cord degenerate and can no longer send signals to muscles.

28 May 2020

Study pinpoints electrophysiological mechanism behind upper motor neuron disease

Scientists from Northwestern Medicine and the University of Belgrade have pinpointed the electrophysiological mechanism behind upper motor neuron disease, unlocking the door to potential treatments for amyotrophic lateral sclerosis and other neurodegenerative diseases, such as Hereditary Spastic Paraplegia and Primary Lateral Sclerosis.

21 May 2020

UC Santa Barbara researcher receives NSF award to study the coordinated behavior of neural circuits

Everything we do comes down to a series of neural signals that translate into physical behaviors. We receive information through our senses, sensory neurons convert this information into electrical and chemical signals that are processed by other neurons in our brains and ultimately, motor neurons fire muscles that move our limbs.

12 May 2020

Motor Neurons News and Research

Scientists find promising drug candidates for treatment of motor neurone disease

Inhibiting STING activation could be new therapeutic strategy to treat ALS and FTD

Study examines safety and early outcomes of gene therapy for spinal muscular atrophy

Combining expertise in organoids and sequencing technologies for ALS research

Study fills crucial knowledge gaps on myasthenia gravis

FDA approves first oral drug for treatment of spinal muscular atrophy

Study: Early training of cell development and network improves response

Neuronal subtypes that drive locomotion in fruit fly reveal an unexpected diversity

Researchers discover new mechanism to explain the effects of subcortical strokes

German researchers recommend early screening and treatment for spinal muscular atrophy

Botox can be an effective treatment for certain sports injuries

Research suggests new approach to therapeutic intervention for ALS

Study provides groundwork for restoring nerve-muscle connection in ALS

Study pinpoints electrophysiological mechanism behind upper motor neuron disease

UC Santa Barbara researcher receives NSF award to study the coordinated behavior of neural circuits

Scientists gain new insight into the pathological mechanisms behind two neurodegenerative diseases

Using Multiplex Assays to Discover Biomarkers for Parkinson’s Disease

Rat spinal cords control muscular behaviors in novel biohybrid robots

Scientists delay onset of amyotrophic lateral sclerosis in mice

Newborn screening for spinal muscular atrophy promises a benefit

Neuroscience - Second Edition eBook

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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