Mouse Model News and Research

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Mechanism that prevents kidney damage in the early stages of diabetes associated with obesity

Northwestern University researchers has identified what they believe is a built-in biological mechanism that prevents kidney damage in the early stages of diabetes associated with obesity.

14 May 2004

Time bomb in heart leads to heart failure in some congenital heart disease patients

However, surgical correction of certain forms of congenital heart disease may not fix the underlying molecular trigger that drives progressive heart failure and sudden death later in life, according to new research from the University of California, San Diego (UCSD) School of Medicine.

29 Apr 2004

Spice turmeric corrects the cystic fibrosis defect

Scientists at The Hospital for Sick Children (Sick Kids) and Yale University School of Medicine have found that a compound in the spice turmeric corrects the cystic fibrosis defect in mice. This research is reported in the April 23, 2004 issue of the journal Science.

24 Apr 2004

Nitric oxide, a chemical messenger involved in bodily functions shuts down a protein involved in Parkinson's disease

Johns Hopkins researchers have discovered that nitric oxide, a chemical messenger involved in bodily functions from erection to nerves' communication, also shuts down a protein involved in Parkinson's disease.

23 Apr 2004

Turmeric corrects the cystic fibrosis defect

22 Apr 2004

An experimental vaccine based on a critical piece of the SARS virus

An experimental vaccine based on a critical piece of the SARS virus protects mice from SARS infection, researchers from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, have found.

19 Apr 2004

Second-hand smoke scars and affects healing

Researchers at the University of California, Riverside have found that breathing “second-hand” smoke reduces the speed at which wounds heal, leading to greater levels of scarring.

17 Apr 2004

Green tea helps kill cells of the most common leukemia

Mayo Clinic researchers have discovered that a component in green tea helps kill cells of the most common leukemia in the United States.

12 Apr 2004

SARS virus vaccine stimulates protective immune response

An experimental vaccine prevents the SARS virus from replicating in laboratory mice, according to a new report in the April 1 issue of Nature. Scientists at the Vaccine Research Center (VRC) of the National Institute of Allergy and Infectious Diseases (NIAID), one of the National Institutes of Health, developed the vaccine. The vaccine was tested in a mouse model of SARS infection recently validated by other NIAID investigators.

31 Mar 2004

Researchers find new purpose for existing drugs to suppress colon cancer metastasis, secure post-radiation brain function, and trick tumors

Drugs approved for treatment of specific maladies sometimes show unexpected benefits. Researchers at the 95th annual meeting of the American Association for Cancer Research demonstrated highlighted how some drugs may one day offer previously unforeseen benefits for patients.

30 Mar 2004

Mouse antibodies neutralise SARS virus

The mouse immune system develops antibodies capable of single-handedly neutralizing the SARS virus, researchers at the National Institute of Allergy and Infectious Diseases (NIAID) report in the April 1 issue of the Journal of Virology, now available online. NIAID is part of the National Institutes of Health (NIH).

22 Mar 2004

Researchers find link that could aid in treatment of kidney cyst diseases

Researchers at UT Southwestern Medical Center at Dallas have uncovered a link between two cyst-forming diseases that affect the kidneys, a finding that could lead to treatments for both a rare form of diabetes and a common kidney disease.

22 Mar 2004